| Metal ion catalysis in the Tetrahymena ribozyme reaction JA Piccirilli, JS Vyle, MH Caruthers, TR Cech Nature 361 (6407), 85-88, 1993 | 528 | 1993 |
| Synthesis and properties of dithymidine phosphate analogues containing 3′-thiothymidine R Cosstick, JS Vyle Nucleic acids research 18 (4), 829-835, 1990 | 102 | 1990 |
| On the dissolution of non-metallic solid elements (sulfur, selenium, tellurium and phosphorus) in ionic liquids E Boros, MJ Earle, MA Gîlea, A Metlen, AV Mudring, F Rieger, ... Chemical communications 46 (5), 716-718, 2010 | 99 | 2010 |
| Reversible photocontrol of deoxyribozyme‐catalyzed RNA cleavage under multiple‐turnover conditions S Keiper, JS Vyle Angewandte Chemie 118 (20), 3384-3387, 2006 | 98 | 2006 |
| Mechanochemistry of nucleosides, nucleotides and related materials O Eguaogie, JS Vyle, PF Conlon, MA Gîlea, Y Liang Beilstein journal of organic chemistry 14 (1), 955-970, 2018 | 72 | 2018 |
| Analysis of DNA processing reactions in bacterial conjugation by using suicide oligonucleotides B Gonzalez‐Perez, M Lucas, LA Cooke, JS Vyle, F De la Cruz, ... The EMBO Journal 26 (16), 3847-3857, 2007 | 71 | 2007 |
| Sequence-and strand-specific cleavage in oligodeoxyribonucleotides and DNA containing 3'-thiothymidine JS Vyle, BA Connolly, D Kemp, R Cosstick Biochemistry 31 (11), 3012-3018, 1992 | 71 | 1992 |
| Solid phase synthesis of oligonucleotides containing 3′-thiothymidine R Cosstick, JS Vyle Tetrahedron letters 30 (35), 4693-4696, 1989 | 70 | 1989 |
| Fast, copper-free click chemistry: a convenient solid-phase approach to oligonucleotide conjugation I Singh, JS Vyle, F Heaney Chemical communications, 3276-3278, 2009 | 48 | 2009 |
| Synthesis of nucleoside analogues in a ball mill: fast, chemoselective and high yielding acylation without undesirable solvents F Ravalico, SL James, JS Vyle Green Chemistry 13 (7), 1778-1783, 2011 | 47 | 2011 |
| Rapid synthesis of nucleotide pyrophosphate linkages in a ball mill F Ravalico, I Messina, MV Berberian, SL James, ME Migaud, JS Vyle Organic and Biomolecular Chemistry 9 (19), 6496-6497, 2011 | 46* | 2011 |
| Fast, quantitative nucleoside protection under solvent-free conditions N Giri, C Bowen, JS Vyle, SL James Green Chemistry 10 (6), 627-628, 2008 | 46 | 2008 |
| New methods for the synthesis of 3′-S-phosphorothiolate internucleoside linkages JS Vyle, X Li, R Cosstick Tetrahedron letters 33 (21), 3017-3020, 1992 | 46 | 1992 |
| Photocontrolled binding and binding-controlled photochromism within anthracene-modified DNA J Manchester, DM Bassani, JLHA Duprey, L Giordano, JS Vyle, Z Zhao, ... Journal of the American Chemical Society 134 (26), 10791-10794, 2012 | 44 | 2012 |
| Dual functional ionic liquids as antimicrobials and plasticisers for medical grade PVCs SY Choi, H Rodríguez, HQN Gunaratne, AV Puga, D Gilpin, S McGrath, ... RSC advances 4 (17), 8567-8581, 2014 | 36 | 2014 |
| Detection of DNA base variation and cytosine methylation at a single nucleotide site using a highly sensitive fluorescent probe JLHA Duprey, Z Zhao, DM Bassani, J Manchester, JS Vyle, JHR Tucker Chemical communications 47 (23), 6629-6631, 2011 | 32 | 2011 |
| Synthesis and phosphorus–sulphur bond cleavage of 3′-thiothymidylyl (3′-5′) thymidine R Cosstick, JS Vyle Journal of the Chemical Society, Chemical Communications, 992-993, 1988 | 32 | 1988 |
| Detection of a single DNA base-pair mismatch using an anthracene-tagged fluorescent probe N Moran, DM Bassani, JP Desvergne, S Keiper, PAS Lowden, JS Vyle, ... Chemical communications, 5003-5005, 2006 | 30 | 2006 |
| Application of the Michaelis–Arbusov reaction to the synthesis of internucleoside 3′-S-phosphorothiolate inkages X Li, GK Scott, AD Baxter, RJ Taylor, JS Vyle, R Cosstick Journal of the Chemical Society, Perkin Transactions 1, 2123-2129, 1994 | 30 | 1994 |
| Novel syntheses of (Z)-alkene and alkane base-modified nucleosides SE Lee, JS Vyle, DM Williams, JA Grasby Tetrahedron Letters 41 (2), 267-270, 2000 | 25 | 2000 |
