michael milsom
michael milsom
HI-STEM & DKFZ, Heidelberg, Germany
Verified email at hi-stem.de - Homepage
TitleCited byYear
Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells
D Walter, A Lier, A Geiselhart, FB Thalheimer, S Huntscha, MC Sobotta, ...
Nature 520 (7548), 549, 2015
2512015
Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis
N Cabezas-Wallscheid, D Klimmeck, J Hansson, DB Lipka, A Reyes, ...
Cell stem cell 15 (4), 507-522, 2014
1982014
Overcoming reprogramming resistance of Fanconi anemia cells
LUW Müller, MD Milsom, CE Harris, R Vyas, KM Brumme, K Parmar, ...
Blood, blood-2012-02-408674, 2012
1242012
Inflammation-induced emergency megakaryopoiesis driven by hematopoietic stem cell-like megakaryocyte progenitors
S Haas, J Hansson, D Klimmeck, D Loeffler, L Velten, H Uckelmann, ...
Cell stem cell 17 (4), 422-434, 2015
1032015
Requirement for CDK6 in MLL-rearranged acute myeloid leukemia
T Placke, K Faber, A Nonami, SL Putwain, HR Salih, FH Heidel, A Krämer, ...
Blood, blood-2014-02-558114, 2014
1032014
Multicistronic lentiviral vectors containing the FMDV 2A cleavage factor demonstrate robust expression of encoded genes at limiting MOI
D Chinnasamy, MD Milsom, J Shaffer, J Neuenfeldt, AF Shaaban, ...
Virology Journal 3 (1), 14, 2006
1002006
miRNA-embedded shRNAs for lineage-specific BCL11A knockdown and hemoglobin F induction
S Guda, C Brendel, R Renella, P Du, DE Bauer, MC Canver, JK Grenier, ...
Molecular Therapy 23 (9), 1465-1474, 2015
522015
Rac1 is essential for intraembryonic hematopoiesis and for the initial seeding of fetal liver with definitive hematopoietic progenitor cells
G Ghiaur, MJ Ferkowicz, MD Milsom, J Bailey, D Witte, JA Cancelas, ...
Blood 111 (7), 3313-3321, 2008
522008
Rapid lentiviral transduction preserves the engraftment potential of Fanca−/− hematopoietic stem cells
LUW Müller, MD Milsom, MO Kim, A Schambach, T Schuesler, ...
Molecular Therapy 16 (6), 1154-1160, 2008
442008
Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype
C Brendel, S Guda, R Renella, DE Bauer, MC Canver, YJ Kim, ...
The Journal of clinical investigation 126 (10), 3868-3878, 2016
392016
The P140K mutant of human O6‐methylguanine‐DNA‐methyltransferase (MGMT) confers resistance in vitro and in vivo to temozolomide in combination with the novel MGMT inactivator …
LB Woolford, TD Southgate, GP Margison, MD Milsom, LJ Fairbairn
The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2006
392006
Enhanced in vivo selection of bone marrow cells by retroviral-mediated coexpression of mutant O6-methylguanine-DNA-methyltransferase and HOXB4
MD Milsom, LB Woolford, GP Margison, RK Humphries, LJ Fairbairn
Molecular Therapy 10 (5), 862-873, 2004
372004
Live and let die: in vivo selection of gene-modified hematopoietic stem cells via MGMT-mediated chemoprotection
MD Milsom, DA Williams
DNA repair 6 (8), 1210-1221, 2007
342007
The European Hematology Association Roadmap for European Hematology Research: a consensus documentThe EHA Roadmap for European Hematology ResearchThe EHA Roadmap for European …
A Engert, C Balduini, A Brand, B Coiffier, C Cordonnier, H Döhner, ...
haematologica 101 (2), 115-208, 2016
312016
Reciprocal relationship between O6-methylguanine-DNA methyltransferase P140K expression level and chemoprotection of hematopoietic stem cells
MD Milsom, M Jerabek-Willemsen, CE Harris, A Schambach, E Broun, ...
Cancer research 68 (15), 6171-6180, 2008
312008
The Rac GTPase effector p21 activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment
AM Dorrance, S De Vita, M Radu, PNG Reddy, MK McGuinness, ...
Blood, blood-2012-10-460709, 2013
302013
Protection and selection for gene therapy in the hematopoietic system
MD Milsom, LJ Fairbairn
The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2004
272004
Stem cell-specific mechanisms ensure genomic fidelity within HSCs and upon aging of HSCs
BM Moehrle, K Nattamai, A Brown, MC Florian, M Ryan, M Vogel, ...
Cell reports 13 (11), 2412-2424, 2015
262015
Early aberrant DNA methylation events in a mouse model of acute myeloid leukemia
M Sonnet, R Claus, N Becker, M Zucknick, J Petersen, DB Lipka, ...
Genome medicine 6 (4), 34, 2014
252014
Ectopic HOXB4 overcomes the inhibitory effect of tumor necrosis factor-α on Fanconi anemia hematopoietic stem and progenitor cells
MD Milsom, B Schiedlmeier, J Bailey, MO Kim, D Li, M Jansen, AM Ali, ...
Blood 113 (21), 5111-5120, 2009
252009
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