Cracking the RNA polymerase II CTD code S Egloff, S Murphy Trends in genetics 24 (6), 280-288, 2008 | 537 | 2008 |
Serine-7 of the RNA polymerase II CTD is specifically required for snRNA gene expression S Egloff, D O'Reilly, RD Chapman, A Taylor, K Tanzhaus, L Pitts, D Eick, ... Science 318 (5857), 1777-1779, 2007 | 366 | 2007 |
U1 snRNA associates with TFIIH and regulates transcriptional initiation KY Kwek, S Murphy, A Furger, B Thomas, W O'Gorman, H Kimura, ... Nature structural biology 9 (11), 800-805, 2002 | 327 | 2002 |
Human 7SL RNA consists of a 140 nucleotide middle-repetitive sequence inserted in an alu sequence E Ullu, S Murphy, M Melli Cell 29 (1), 195-202, 1982 | 258 | 1982 |
The in vitro transcription of the 7SK RNA gene by RNA polymerase III is dependent only on the presence of an upstream promoter S Murphy, C Di Liegro, M Melli Cell 51 (1), 81-87, 1987 | 241 | 1987 |
The pol II CTD: new twists in the tail J Zaborowska, S Egloff, S Murphy Nature structural & molecular biology 23 (9), 771-777, 2016 | 239 | 2016 |
Oct-1 and Oct-2 potentiate functional interactions of a transcription factor with the proximal sequence element of small nuclear RNA genes S Murphy, JB Yoon, T Gerster, RG Roeder Molecular and cellular biology 12 (7), 3247-3261, 1992 | 224 | 1992 |
Updating the RNA polymerase CTD code: adding gene-specific layers S Egloff, M Dienstbier, S Murphy Trends in Genetics 28 (7), 333-341, 2012 | 217 | 2012 |
DOT1L and H3K79 methylation in transcription and genomic stability K Wood, M Tellier, S Murphy Biomolecules 8 (1), 11, 2018 | 197 | 2018 |
Regional and temporal specialization in the nucleus: a transcriptionally-active nuclear domain rich in PTF, Oct1 and PIKA antigens associates with specific chromosomes early in … A Pombo, P Cuello, W Schul, JB Yoon, RG Roeder, PR Cook, S Murphy The EMBO journal 17 (6), 1768-1778, 1998 | 176 | 1998 |
Deregulated expression of mammalian lncRNA through loss of SPT6 induces R-loop formation, replication stress, and cellular senescence T Nojima, M Tellier, J Foxwell, CR de Almeida, SM Tan-Wong, S Dhir, ... Molecular cell 72 (6), 970-984. e7, 2018 | 174 | 2018 |
Proximal sequence element-binding transcription factor (PTF) is a multisubunit complex required for transcription of both RNA polymerase II-and RNA polymerase III-dependent … JB Yoon, S Murphy, L Bai, Z Wang, RG Roeder Molecular and cellular biology 15 (4), 2019-2027, 1995 | 167 | 1995 |
Ser7 phosphorylation of the CTD recruits the RPAP2 Ser5 phosphatase to snRNA genes S Egloff, J Zaborowska, C Laitem, T Kiss, S Murphy Molecular cell 45 (1), 111-122, 2012 | 164 | 2012 |
The integrator complex recognizes a new double mark on the RNA polymerase II carboxyl-terminal domain S Egloff, SA Szczepaniak, M Dienstbier, A Taylor, S Knight, S Murphy Journal of Biological Chemistry 285 (27), 20564-20569, 2010 | 136 | 2010 |
CDK9 inhibitors define elongation checkpoints at both ends of RNA polymerase II–transcribed genes C Laitem, J Zaborowska, NF Isa, J Kufs, M Dienstbier, S Murphy Nature structural & molecular biology 22 (5), 396-403, 2015 | 133 | 2015 |
Expression of human snRNA genes from beginning to end S Egloff, D O'Reilly, S Murphy Biochemical Society Transactions 36 (4), 590-594, 2008 | 126 | 2008 |
The C-terminal domain of pol II and a DRB-sensitive kinase are required for 3′ processing of U2 snRNA JE Medlin, P Uguen, A Taylor, DL Bentley, S Murphy The EMBO journal 22 (4), 925-934, 2003 | 115 | 2003 |
Purified octamer binding transcription factors stimulate RNA polymerase III-mediated transcription of the 7SK RNA gene S Murphy, A Pierani, C Scheidereit, M Melli, RG Roeder Cell 59 (6), 1071-1080, 1989 | 114 | 1989 |
P‐TEFb is not an essential elongation factor for the intronless human U2 snRNA and histone H2b genes J Medlin, A Scurry, A Taylor, F Zhang, BM Peterlin, S Murphy The EMBO journal 24 (23), 4154-4165, 2005 | 109 | 2005 |
RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation Z Ni, C Xu, X Guo, GO Hunter, OV Kuznetsova, W Tempel, E Marcon, ... Nature structural & molecular biology 21 (8), 686-695, 2014 | 99 | 2014 |