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Isaac E. García Carrillo
Isaac E. García Carrillo
Associate Professor, Universidad de Valparaiso, PhD, Adjunct Researcher CINV
Verified email at uv.cl
Title
Cited by
Cited by
Year
Diseases associated with leaky hemichannels
MA Retamal, EP Reyes, IE García, B Pinto, AD Martínez, C González
Frontiers in cellular neuroscience 9, 267, 2015
992015
Keratitis-ichthyosis-deafness syndrome-associated Cx26 mutants produce nonfunctional gap junctions but hyperactive hemichannels when co-expressed with wild type Cx43
IE García, J Maripillán, O Jara, R Ceriani, A Palacios-Munoz, ...
Journal of Investigative Dermatology 135 (5), 1338-1347, 2015
902015
Connexinopathies: a structural and functional glimpse
IE García, P Prado, A Pupo, O Jara, D Rojas-Gómez, P Mujica, ...
BMC cell biology 17, 71-87, 2016
572016
Critical role of the first transmembrane domain of Cx26 in regulating oligomerization and function
O Jara, R Acuña, IE García, J Maripillán, V Figueroa, JC Sáez, ...
Molecular biology of the cell 23 (17), 3299-3311, 2012
532012
From hyperactive connexin26 hemichannels to impairments in epidermal calcium gradient and permeability barrier in the keratitis-ichthyosis-deafness syndrome
IE Garcia, F Bosen, P Mujica, A Pupo, C Flores-Munoz, O Jara, ...
Journal of Investigative Dermatology 136 (3), 574-583, 2016
522016
Characterization of a novel water pocket inside the human Cx26 hemichannel structure
R Araya-Secchi, T Perez-Acle, S Kang, T Huynh, A Bernardin, Y Escalona, ...
Biophysical journal 107 (3), 599-612, 2014
432014
Extracellular cysteine in connexins: role as redox sensors
MA Retamal, IE García, BI Pinto, A Pupo, D Báez, J Stehberg, R Del Rio, ...
Frontiers in physiology 7, 171782, 2016
382016
Abnormal distribution of inositol 1, 4, 5‐trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy‐derived cells
C Cárdenas, N Juretić, JA Bevilacqua, IE García, R Figueroa, R Hartley, ...
The FASEB Journal 24 (9), 3210-3221, 2010
282010
Redox-mediated regulation of connexin proteins; focus on nitric oxide
IE Garcia, HA Sánchez, AD Martinez, MA Retamal
Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (1), 91-95, 2018
252018
Role of connexin channels in the retinal light response of a diurnal rodent
A Palacios-Muñoz, MJ Escobar, A Vielma, J Araya, A Astudillo, G Valdivia, ...
Frontiers in cellular neuroscience 8, 249, 2014
242014
The syndromic deafness mutation G12R impairs fast and slow gating in Cx26 hemichannels
IE García, F Villanelo, GF Contreras, A Pupo, BI Pinto, JE Contreras, ...
Journal of General Physiology 150 (5), 697-711, 2018
172018
The connexin26 human mutation N14K disrupts cytosolic intersubunit interactions and promotes channel opening
JM Valdez Capuccino, P Chatterjee, IE García, WM Botello-Smith, ...
Journal of General Physiology 151 (3), 328-341, 2019
152019
Restraint of human skin fibroblast motility, migration, and cell surface actin dynamics, by Pannexin 1 and P2X7 receptor signaling
C Flores-Muñoz, J Maripillán, J Vásquez-Navarrete, J Novoa-Molina, ...
International Journal of Molecular Sciences 22 (3), 1069, 2021
142021
Calcium binding and voltage gating in Cx46 hemichannels
BI Pinto, A Pupo, IE García, K Mena-Ulecia, AD Martínez, R Latorre, ...
Scientific Reports 7 (1), 15851, 2017
132017
Charged residues at the first transmembrane region contribute to the voltage dependence of the slow gate of connexins
BI Pinto, IE García, A Pupo, MA Retamal, AD Martínez, R Latorre, ...
Journal of Biological Chemistry 291 (30), 15740-15752, 2016
132016
Mutations in trpγ, the homologue of TRPC6 autism candidate gene, causes autism-like behavioral deficits in Drosophila
A Palacios-Muñoz, D de Paula Moreira, V Silva, IE García, F Aboitiz, ...
Molecular Psychiatry 27 (8), 3328-3342, 2022
72022
Therapeutic perspectives of HIV-associated chemokine receptor (CCR5 and CXCR4) antagonists in carcinomas
WA González-Arriagada, IE García, R Martínez-Flores, S Morales-Pison, ...
International Journal of Molecular Sciences 24 (1), 478, 2022
52022
Expression of KID syndromic mutation Cx26S17F produces hyperactive hemichannels in supporting cells of the organ of Corti
AC Abbott, IE García, F Villanelo, C Flores-Muñoz, R Ceriani, J Maripillán, ...
Frontiers in Cell and Developmental Biology 10, 1071202, 2023
22023
Insights on Gating Functions of Cytosolic Domains of Connexin26 Hemichannels Revealed by a Human Pathogenic Mutation (N14K)
JMV Capuccino, P Chatterjee, I Garcia, AL Harris, Y Luo, JE Contreras
Biophysical Journal 114 (3), 379a, 2018
12018
Is the gain of hemichannel activity a common feature shared by Cx26 syndromic deafness mutants?
IE García, MA Retamal, O Jara, C González, AD Martínez
Biophysical Journal 104 (2), 492a-493a, 2013
12013
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