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Methylation of the 5′ CpG Island of the FHIT Gene Is Closely Associated with Transcriptional Inactivation in Esophageal Squamous Cell Carcinomas H Tanaka, Y Shimada, H Harada, M Shinoda, S Hatooka, M Imamura, ... Cancer research 58 (15), 3429-3434, 1998 | 214 | 1998 |
In oesophageal squamous cell carcinoma vascular endothelial growth factor is associated with p53 mutation, advanced stage and poor prognosis S Uchida, Y Shimada, G Watanabe, H Tanaka, I Shibagaki, T Miyahara, ... British journal of cancer 77 (10), 1704-1709, 1998 | 174 | 1998 |
DNA methylation of developmental genes in pediatric medulloblastomas identified by denaturation analysis of methylation differences SJ Diede, J Guenthoer, LN Geng, SE Mahoney, M Marotta, JM Olson, ... Proceedings of the National Academy of Sciences 107 (1), 234-239, 2010 | 159* | 2010 |
FOXC1 Activates Smoothened-Independent Hedgehog Signaling in Basal-like Breast Cancer Cell Report 13 (5), 1046–1058, 2015 | 142 | 2015 |
Short inverted repeats initiate gene amplification through the formation of a large DNA palindrome in mammalian cells H Tanaka, SJ Tapscott, BJ Trask, MC Yao Proceedings of the National Academy of Sciences 99 (13), 8772-8777, 2002 | 128 | 2002 |
Widespread and nonrandom distribution of DNA palindromes in cancer cells provides a structural platform for subsequent gene amplification H Tanaka, DA Bergstrom, MC Yao, SJ Tapscott Nature genetics 37 (3), 320-327, 2005 | 121 | 2005 |
Palindromic gene amplification—an evolutionarily conserved role for DNA inverted repeats in the genome H Tanaka, MC Yao Nature Reviews Cancer 9 (3), 216-224, 2009 | 110 | 2009 |
BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II–DNA complexes H Sasanuma, M Tsuda, S Morimoto, LK Saha, MM Rahman, Y Kiyooka, ... Proceedings of the National Academy of Sciences 115 (45), E10642-E10651, 2018 | 85 | 2018 |
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Genetic alterations in patients with esophageal cancer with short-and long-term survival rates after curative esophagectomy Y Shimada, M Imamura, I Shibagaki, H Tanaka, T Miyahara, M Kato, ... Annals of surgery 226 (2), 162-168, 1997 | 77 | 1997 |
FOXC1-induced non-canonical WNT5A-MMP7 signaling regulates invasiveness in triple-negative breast cancer B Han, B Zhou, Y Qu, B Gao, Y Xu, S Chung, H Tanaka, W Yang, ... Oncogene 37 (10), 1399-1408, 2018 | 74 | 2018 |
Multiple types of aberrations in the p16 (INK4a) and the p15 (INK4b) genes in 30 esophageal squamous‐cell‐carcinoma cell lines H Tanaka, Y Shimada, M Imamura, I Shibagaki, K Ishizaki International journal of cancer 70 (4), 437-442, 1997 | 72 | 1997 |
Intrastrand annealing leads to the formation of a large DNA palindrome and determines the boundaries of genomic amplification in human cancer H Tanaka, Y Cao, DA Bergstrom, C Kooperberg, SJ Tapscott, MC Yao Molecular and cellular biology 27 (6), 1993-2002, 2007 | 66 | 2007 |
Characterization of p53 gene mutations in esophageal squamous cell carcinoma cell lines: increased frequency and different spectrum of mutations from primary tumors H Tanaka, I Shibagaki, Y Shimada, T Wagata, M Imamura, K Ishizaki International journal of cancer 65 (3), 372-376, 1996 | 60 | 1996 |
Linkage disequilibrium between two high-frequency deletion polymorphisms: implications for association studies involving the glutathione-S transferase (GST) genes Y Zhao, M Marotta, EE Eichler, C Eng, H Tanaka PLoS genetics 5 (5), e1000472, 2009 | 58 | 2009 |
Emerin deregulation links nuclear shape instability to metastatic potential M Reis-Sobreiro, JF Chen, T Novitskaya, S You, S Morley, K Steadman, ... Cancer Research 78 (21), 6086-6097, 2018 | 56 | 2018 |
Mechanisms underlying recurrent genomic amplification in human cancers H Tanaka, T Watanabe Trends in cancer 6 (6), 462-477, 2020 | 55 | 2020 |
Numerical analysis of the airflow around automobiles using multi-block structured grids R Himeno, M Takagi, K Fujitani, H Tanaka SAE Technical Paper, 1990 | 54 | 1990 |
Tumors defective in homologous recombination rely on oxidative metabolism: relevance to treatments with PARP inhibitors Á Lahiguera, P Hyroššová, A Figueras, D Garzón, R Moreno, ... EMBO molecular medicine 12 (6), e11217, 2020 | 46 | 2020 |