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| The absolute quantification strategy: a general procedure for the quantification of proteins and post-translational modifications DS Kirkpatrick, SA Gerber, SP Gygi Methods 35 (3), 265-273, 2005 | 724 | 2005 |
| Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain F Huang, D Kirkpatrick, X Jiang, S Gygi, A Sorkin Molecular cell 21 (6), 737-748, 2006 | 663 | 2006 |
| Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies K Newton, ML Matsumoto, IE Wertz, DS Kirkpatrick, JR Lill, J Tan, ... Cell 134 (4), 668-678, 2008 | 653 | 2008 |
| Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases JMM Tan, ESP Wong, DS Kirkpatrick, O Pletnikova, HS Ko, SP Tay, ... Human molecular genetics 17 (3), 431-439, 2008 | 531 | 2008 |
| Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology DS Kirkpatrick, NA Hathaway, J Hanna, S Elsasser, J Rush, D Finley, ... Nature cell biology 8 (7), 700-710, 2006 | 512 | 2006 |
| K11-linked polyubiquitination in cell cycle control revealed by a K11 linkage-specific antibody ML Matsumoto, KE Wickliffe, KC Dong, C Yu, I Bosanac, D Bustos, L Phu, ... Molecular cell 39 (3), 477-484, 2010 | 465 | 2010 |
| Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome CJ Westlake, LM Baye, MV Nachury, KJ Wright, KE Ervin, L Phu, ... Proceedings of the National Academy of Sciences 108 (7), 2759-2764, 2011 | 442 | 2011 |
| Loss of the tumor suppressor BAP1 causes myeloid transformation A Dey, D Seshasayee, R Noubade, DM French, J Liu, MS Chaurushiya, ... Science 337 (6101), 1541-1546, 2012 | 431 | 2012 |
| Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation J Hanna, NA Hathaway, Y Tone, B Crosas, S Elsasser, DS Kirkpatrick, ... Cell 127 (1), 99-111, 2006 | 428 | 2006 |
| Ser1292 autophosphorylation is an indicator of LRRK2 kinase activity and contributes to the cellular effects of PD mutations Z Sheng, S Zhang, D Bustos, T Kleinheinz, CE Le Pichon, SL Dominguez, ... Science translational medicine 4 (164), 164ra161-164ra161, 2012 | 394 | 2012 |
| c‐IAP1 and UbcH5 promote K11‐linked polyubiquitination of RIP1 in TNF signalling JN Dynek, T Goncharov, EC Dueber, AV Fedorova, A Izrael‐Tomasevic, ... The EMBO journal 29 (24), 4198-4209, 2010 | 394 | 2010 |
| Ubiquitin chains are remodeled at the proteasome by opposing ubiquitin ligase and deubiquitinating activities B Crosas, J Hanna, DS Kirkpatrick, DP Zhang, Y Tone, NA Hathaway, ... Cell 127 (7), 1401-1413, 2006 | 367 | 2006 |
| USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria CN Cunningham, JM Baughman, L Phu, JS Tea, C Yu, M Coons, ... Nature cell biology 17 (2), 160-169, 2015 | 323 | 2015 |
| Weighing in on ubiquitin: the expanding role of mass-spectrometry-based proteomics DS Kirkpatrick, C Denison, SP Gygi Nature cell biology 7 (8), 750-757, 2005 | 267 | 2005 |
| Discovery of novel blood-brain barrier targets to enhance brain uptake of therapeutic antibodies YJY Zuchero, X Chen, N Bien-Ly, D Bumbaca, RK Tong, X Gao, S Zhang, ... Neuron 89 (1), 70-82, 2016 | 249 | 2016 |
| Ubiquitin ligase RNF146 regulates tankyrase and Axin to promote Wnt signaling MG Callow, H Tran, L Phu, T Lau, J Lee, WN Sandoval, PS Liu, ... PloS one 6 (7), e22595, 2011 | 224 | 2011 |
| Ubiquitin binding to A20 ZnF4 is required for modulation of NF-κB signaling I Bosanac, IE Wertz, B Pan, C Yu, S Kusam, C Lam, L Phu, Q Phung, ... Molecular cell 40 (4), 548-557, 2010 | 219 | 2010 |
| APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1 NV Dimova, NA Hathaway, BH Lee, DS Kirkpatrick, ML Berkowitz, ... Nature cell biology 14 (2), 168-176, 2012 | 171 | 2012 |
| OTULIN limits cell death and inflammation by deubiquitinating LUBAC K Heger, KE Wickliffe, A Ndoja, J Zhang, A Murthy, DL Dugger, ... Nature 559 (7712), 120-124, 2018 | 164 | 2018 |
Vishva Dixitvice-president, GenentechVerified email at gene.com
