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Giovanni Lentini
Giovanni Lentini
Professore di Chimica Farmaceutica
Bestätigte E-Mail-Adresse bei uniba.it
Titel
Zitiert von
Zitiert von
Jahr
The chemistry and pharmacology of citrus limonoids
R Gualdani, MM Cavalluzzi, G Lentini, S Habtemariam
Molecules 21 (11), 1530, 2016
1652016
Plant-derived anticancer agents: Lessons from the pharmacology of geniposide and its aglycone, genipin
S Habtemariam, G Lentini
Biomedicines 6 (2), 39, 2018
942018
Ligand efficiency metrics in drug discovery: The pros and cons from a practical perspective
MM Cavalluzzi, GF Mangiatordi, O Nicolotti, G Lentini
Expert opinion on drug discovery 12 (11), 1087-1104, 2017
802017
A mini-review on thalidomide: chemistry, mechanisms of action, therapeutic potential and anti-angiogenic properties in multiple myeloma
A Mercurio, G Adriani, A Catalano, A Carocci, L Rao, G Lentini, ...
Current medicinal chemistry 24 (25), 2736-2744, 2017
802017
Molecular determinants of mexiletine structure for potent and use-dependent block of skeletal muscle sodium channels
A De Luca, F Natuzzi, JF Desaphy, G Loni, G Lentini, C Franchini, ...
Molecular Pharmacology 57 (2), 268-277, 2000
672000
The therapeutic potential of rutin for diabetes: an update
S Habtemariam, G Lentini
Mini Reviews in Medicinal Chemistry 15 (7), 524-528, 2015
662015
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels
C Franchini, A Carocci, A Catalano, MM Cavalluzzi, F Corbo, G Lentini, ...
Journal of medicinal chemistry 46 (24), 5238-5248, 2003
662003
Phytochemical, Antioxidant and Anti‐α‐glucosidase Activity Evaluations of Bergenia cordifolia
M Roselli, G Lentini, S Habtemariam
Phytotherapy Research 26 (6), 908-914, 2012
642012
New N-(phenoxydecyl) phthalimide derivatives displaying potent inhibition activity towards α-glucosidase
R Pascale, A Carocci, A Catalano, G Lentini, A Spagnoletta, ...
Bioorganic & medicinal chemistry 18 (16), 5903-5914, 2010
592010
Stereospecific synthesis of mexiletine and related compounds: Mitsunobu versus Williamson reaction
A Carocci, A Catalano, F Corbo, A Duranti, R Amoroso, C Franchini, ...
Tetrahedron: Asymmetry 11 (17), 3619-3634, 2000
592000
Targeting the pregnane X receptor using microbial metabolite mimicry
Z Dvořák, F Kopp, CM Costello, JS Kemp, H Li, A Vrzalová, M Štěpánková, ...
EMBO molecular medicine 12 (4), e11621, 2020
552020
Old drug scaffold, new activity: thalidomide‐correlated compounds exert different effects on breast cancer cell growth and progression
D Iacopetta, A Carocci, MS Sinicropi, A Catalano, G Lentini, J Ceramella, ...
ChemMedChem 12 (5), 381-389, 2017
552017
Stereoselective effects of mexiletine enantiomers on sodium currents and excitability characteristics of adult skeletal muscle fibers
A De Luca, F Natuzzi, G Lentini, C Franchini, V Tortorella, ...
Naunyn-Schmiedeberg's archives of pharmacology 352, 653-661, 1995
531995
COVID-19, chloroquine repurposing, and cardiac safety concern: chirality might help
G Lentini, MM Cavalluzzi, S Habtemariam
Molecules 25 (8), 1834, 2020
482020
Evaluation of the antimyotonic activity of mexiletine and some new analogs on sodium currents of single muscle fibers and on the abnormal excitability of the myotonic ADR mouse
A De Luca, S Pierno, F Natuzzi, C Franchini, A Duranti, G Lentini, ...
Journal of Pharmacology and Experimental Therapeutics 282 (1), 93-100, 1997
481997
Inhibition of frog skeletal muscle sodium channels by newly synthesized chiral derivatives of mexiletine and tocainide
A De Luca, F Natuzzi, G Falcone, A Duranti, G Lentini, C Franchini, ...
Naunyn-Schmiedeberg's archives of pharmacology 356, 777-787, 1997
451997
Human ether-à-go-go-related potassium channel: Exploring SAR to improve drug design
MM Cavalluzzi, P Imbrici, R Gualdani, A Stefanachi, GF Mangiatordi, ...
Drug Discovery Today 25 (2), 344-366, 2020
422020
Design, synthesis, and pharmacological effects of structurally simple ligands for MT1 and MT2 melatonin receptors
A Carocci, A Catalano, A Lovece, G Lentini, A Duranti, V Lucini, ...
Bioorganic & medicinal chemistry 18 (17), 6496-6511, 2010
422010
Synthesis of (R)-,(S)-, and (RS)-hydroxymethylmexiletine, one of the major metabolites of mexiletine
MM Cavalluzzi, A Catalano, C Bruno, A Lovece, A Carocci, F Corbo, ...
Tetrahedron: Asymmetry 18 (20), 2409-2417, 2007
412007
Structure-based prediction of hERG-related cardiotoxicity: A benchmark study
TM Creanza, P Delre, N Ancona, G Lentini, M Saviano, GF Mangiatordi
Journal of Chemical Information and Modeling 61 (9), 4758-4770, 2021
402021
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