| High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq J Schödel, S Oikonomopoulos, J Ragoussis, CW Pugh, PJ Ratcliffe, ... Blood, The Journal of the American Society of Hematology 117 (23), e207-e217, 2011 | 812 | 2011 |
| Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival H Choudhry, A Albukhari, M Morotti, S Haider, D Moralli, J Smythies, ... Oncogene 34 (34), 4482-4490, 2015 | 342 | 2015 |
| Hypoxia, hypoxia-inducible transcription factors, and renal cancer J Schödel, S Grampp, ER Maher, H Moch, PJ Ratcliffe, P Russo, DR Mole European urology 69 (4), 646-657, 2016 | 322 | 2016 |
| The lysyl oxidases LOX and LOXL2 are necessary and sufficient to repress E-cadherin in hypoxia: insights into cellular transformation processes mediated by HIF-1 R Schietke, C Warnecke, I Wacker, J Schödel, DR Mole, V Campean, ... Journal of Biological Chemistry 285 (9), 6658-6669, 2010 | 294 | 2010 |
| Mechanisms of hypoxia signalling: new implications for nephrology J Schödel, PJ Ratcliffe Nature Reviews Nephrology 15 (10), 641-659, 2019 | 252 | 2019 |
| Hypoxia‐inducible protein 2 is a novel lipid droplet protein and a specific target gene of hypoxia‐inducible factor‐1 T Gimm, M Wiese, B Teschemacher, A Deggerich, J Schödel, KX Knaup, ... The FASEB Journal 24 (11), 4443-4458, 2010 | 186 | 2010 |
| Common genetic variants at the 11q13. 3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression J Schödel, C Bardella, LK Sciesielski, JM Brown, CW Pugh, V Buckle, ... Nature genetics 44 (4), 420-425, 2012 | 178 | 2012 |
| miR-210 is a target of hypoxia-inducible factors 1 and 2 in renal cancer, regulates ISCU and correlates with good prognosis RI McCormick, C Blick, J Ragoussis, J Schoedel, DR Mole, AC Young, ... British journal of cancer 108 (5), 1133-1142, 2013 | 168 | 2013 |
| Donor treatment with a PHD-inhibitor activating HIFs prevents graft injury and prolongs survival in an allogenic kidney transplant model WM Bernhardt, U Gottmann, F Doyon, B Buchholz, V Campean, J Schödel, ... Proceedings of the National Academy of Sciences 106 (50), 21276-21281, 2009 | 165 | 2009 |
| Extensive regulation of the non‐coding transcriptome by hypoxia: role of HIF in releasing paused RNA pol2 H Choudhry, J Schödel, S Oikonomopoulos, C Camps, S Grampp, ... EMBO reports 15 (1), 70-76, 2014 | 164 | 2014 |
| Regulation of type II transmembrane serine proteinase TMPRSS6 by hypoxia-inducible factors: new link between hypoxia signaling and iron homeostasis S Lakhal, J Schödel, ARM Townsend, CW Pugh, PJ Ratcliffe, DR Mole Journal of Biological Chemistry 286 (6), 4090-4097, 2011 | 156 | 2011 |
| Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1α (HIF-1α) A Thalhammer, Z Bencokova, R Poole, C Loenarz, J Adam, L O'Flaherty, ... PloS one 6 (1), e16210, 2011 | 152 | 2011 |
| Toll-like receptor activation and hypoxia use distinct signaling pathways to stabilize hypoxia-inducible factor 1α (HIF1A) and result in differential HIF1A-dependent gene … J Jantsch, M Wiese, J Schödel, K Castiglione, J Gläsner, S Kolbe, D Mole, ... Journal of leukocyte biology 90 (3), 551-562, 2011 | 122 | 2011 |
| Optimal translational termination requires C4 lysyl hydroxylation of eRF1 T Feng, A Yamamoto, SE Wilkins, E Sokolova, LA Yates, M Münzel, ... Molecular cell 53 (4), 645-654, 2014 | 118 | 2014 |
| Hypoxia-inducible transcription factors stabilization in the thick ascending limb protects against ischemic acute kidney injury G Schley, B Klanke, J Schödel, F Forstreuter, D Shukla, A Kurtz, K Amann, ... Journal of the American Society of Nephrology 22 (11), 2004-2015, 2011 | 112 | 2011 |
| Ferritin-mediated iron sequestration stabilizes hypoxia-inducible factor-1α upon LPS activation in the presence of ample oxygen I Siegert, J Schödel, M Nairz, V Schatz, K Dettmer, C Dick, J Kalucka, ... Cell reports 13 (10), 2048-2055, 2015 | 110 | 2015 |
| Tuning the transcriptional response to hypoxia by inhibiting hypoxia-inducible factor (HIF) prolyl and asparaginyl hydroxylases MC Chan, NE Ilott, J Schödel, D Sims, A Tumber, K Lippl, DR Mole, ... Journal of Biological Chemistry 291 (39), 20661-20673, 2016 | 108 | 2016 |
| HIF-prolyl hydroxylases in the rat kidney: physiologic expression patterns and regulation in acute kidney injury J Schödel, B Klanke, A Weidemann, B Buchholz, W Bernhardt, M Bertog, ... The American journal of pathology 174 (5), 1663-1674, 2009 | 103 | 2009 |
| Pan-genomic binding of hypoxia-inducible transcription factors J Schödel, DR Mole, PJ Ratcliffe Biological chemistry 394 (4), 507-517, 2013 | 101 | 2013 |
| Renal tubular HIF-2α expression requires VHL inactivation and causes fibrosis and cysts RE Schietke, T Hackenbeck, M Tran, R Günther, B Klanke, CL Warnecke, ... PloS one 7 (1), e31034, 2012 | 100 | 2012 |
