Brca1 breast tumors contain distinct CD44+/CD24- and CD133+cells with cancer stem cell characteristics MH Wright, AM Calcagno, CD Salcido, MD Carlson, SV Ambudkar, ... Breast cancer research 10, 1-16, 2008 | 824 | 2008 |
The knockout mouse project Nature genetics 36 (9), 921-924, 2004 | 760 | 2004 |
Hypoxia induces vascular endothelial growth factor in cultured human endothelial cells (∗) A Namiki, E Brogi, M Kearney, EA Kim, T Wu, T Couffinhal, L Varticovski, ... Journal of Biological Chemistry 270 (52), 31189-31195, 1995 | 665 | 1995 |
The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane U Bandyopadhyay, S Kaushik, L Varticovski, AM Cuervo Molecular and cellular biology 28 (18), 5747-5763, 2008 | 615 | 2008 |
Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression. E Brogi, G Schatteman, T Wu, EA Kim, L Varticovski, B Keyt, JM Isner The Journal of clinical investigation 97 (2), 469-476, 1996 | 530 | 1996 |
The colony stimulating factor-1 receptor associates with and activates phosphatidylinositol-3 kinase L Varticovski, B Druker, D Morrison, L Cantley, T Roberts Nature 342 (6250), 699-702, 1989 | 377 | 1989 |
Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models E Caldas-Lopes, L Cerchietti, JH Ahn, CC Clement, AI Robles, A Rodina, ... Proceedings of the National Academy of Sciences 106 (20), 8368-8373, 2009 | 371 | 2009 |
Prolonged drug selection of breast cancer cells and enrichment of cancer stem cell characteristics AM Calcagno, CD Salcido, JP Gillet, CP Wu, JM Fostel, MD Mumau, ... Journal of the National Cancer Institute 102 (21), 1637-1652, 2010 | 330 | 2010 |
Activation of phosphatidylinositol 3-kinase in cells expressing abl oncogene variants L Varticovski, GQ Daley, P Jackson, D Baltimore, LC Cantley Molecular and cellular biology, 1991 | 299 | 1991 |
Signal transduction through the EGF receptor transfected in IL-3-dependent hematopoietic cells JH Pierce, M Ruggiero, TP Fleming, PP Di Fiore, JS Greenberger, ... Science 239 (4840), 628-631, 1988 | 278 | 1988 |
Chaperone-mediated autophagy is required for tumor growth M Kon, R Kiffin, H Koga, J Chapochnick, F Macian, L Varticovski, ... Science translational medicine 3 (109), 109ra117-109ra117, 2011 | 267 | 2011 |
In Vitro Evidence That Myocardial Ischemia Resulting from 5-Fluorouracil Chemotherapy Is Due to Protein Kinase C-mediated Vasoconstriction of Vascular Smooth … M Mosseri, HJ Fingert, L Varticovski, S Chokshi, JM Isner Cancer research 53 (13), 3028-3033, 1993 | 235 | 1993 |
A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6–dependent B cell lymphomas LC Cerchietti, EC Lopes, SN Yang, K Hatzi, KL Bunting, LA Tsikitas, ... Nature medicine 15 (12), 1369-1376, 2009 | 207 | 2009 |
Molecular characterisation of side population cells with cancer stem cell-like characteristics in small-cell lung cancer CD Salcido, A Larochelle, BJ Taylor, CE Dunbar, L Varticovski British journal of cancer 102 (11), 1636-1644, 2010 | 203 | 2010 |
Interleukin-2 receptor regulates activation of phosphatidylinositol 3-kinase B Remillard, R Petrillo, W Maslinski, M Tsudo, TB Strom, L Cantley, ... Journal of Biological Chemistry 266 (22), 14167-14170, 1991 | 197 | 1991 |
Role of PI 3-kinase in angiopoietin-1-mediated migration and attachment-dependent survival of endothelial cells K Fujikawa, I de Aos Scherpenseel, SK Jain, E Presman, L Varticovski Experimental cell research 253 (2), 663-672, 1999 | 190 | 1999 |
with tyrosine phosphorylated Stats D Frank, L Varticovski Leukemia 10, 1724-1730, 1996 | 176 | 1996 |
Phosphatidylinositol 3-kinase and its novel product, phosphatidylinositol 3-phosphate, are present in Saccharomyces cerevisiae KR Auger, CL Carpenter, LC Cantley, L Varticovski Journal of Biological Chemistry 264 (34), 20181-20184, 1989 | 167 | 1989 |
The role of phosphoinositide 3-kinase in taurocholate-induced trafficking of ATP-dependent canalicular transporters in rat liver S Misra, P Ujházy, Z Gatmaitan, L Varticovski, IM Arias Journal of Biological Chemistry 273 (41), 26638-26644, 1998 | 156 | 1998 |
Inhibitor of growth 4 suppresses cell spreading and cell migration by interacting with a novel binding partner, liprin α1 JC Shen, M Unoki, D Ythier, A Duperray, L Varticovski, K Kumamoto, ... Cancer research 67 (6), 2552-2558, 2007 | 154 | 2007 |