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Silvia Lovera
Silvia Lovera
UCB BioPharma
Verified email at ucb.com
Title
Cited by
Cited by
Year
The different flexibility of c-Src and c-Abl kinases regulates the accessibility of a druggable inactive conformation
S Lovera, L Sutto, R Boubeva, L Scapozza, N Dölker, FL Gervasio
Journal of the American Chemical Society 134 (5), 2496-2499, 2012
1182012
Conformational selection and induced fit mechanisms in the binding of an anticancer drug to the c-Src kinase
MA Morando, G Saladino, N D’Amelio, E Pucheta-Martinez, S Lovera, ...
Scientific reports 6 (1), 24439, 2016
772016
Towards a molecular understanding of the link between imatinib resistance and kinase conformational dynamics
S Lovera, M Morando, E Pucheta-Martinez, JL Martinez-Torrecuadrada, ...
PLoS computational biology 11 (11), e1004578, 2015
672015
Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist
B Sun, D Feng, MLH Chu, I Fish, S Lovera, ZA Sands, S Kelm, A Valade, ...
Nature communications 12 (1), 3305, 2021
392021
Defining the architecture of KPC-2 Carbapenemase: identifying allosteric networks to fight antibiotics resistance
I Galdadas, S Lovera, G Pérez-Hernández, MD Barnes, J Healy, ...
Scientific Reports 8 (1), 12916, 2018
332018
Reconstruction of apo A2A receptor activation pathways reveal ligand-competent intermediates and state-dependent cholesterol hotspots
S Lovera, A Cuzzolin, S Kelm, G De Fabritiis, ZA Sands
Scientific Reports 9 (1), 14199, 2019
282019
PlayMolecule CrypticScout: predicting protein cryptic sites using mixed-solvent molecular simulations
G Martinez-Rosell, S Lovera, ZA Sands, G De Fabritiis
Journal of Chemical Information and Modeling 60 (4), 2314-2324, 2020
162020
NaViA: a program for the visual analysis of complex mass spectra
D Quetschlich, TK Esser, TD Newport, F Fiorentino, D Shutin, S Chen, ...
Bioinformatics 37 (24), 4876-4878, 2021
112021
The Aminotriazole Antagonist Cmpd‐1 Stabilises a Novel Inactive State of the Adenosine 2A Receptor
EJB Landin, S Lovera, G de Fabritiis, S Kelm, J Mercier, D MacMillan, ...
Angewandte Chemie, 2019
62019
Deconstructing allostery by computational assessment of the binding determinants of allosteric PTP1B modulators
A Hardie, BP Cossins, S Lovera, J Michel
Communications Chemistry 6 (1), 125, 2023
22023
Exploring the role of conformational dynamics in the regulation of tyrosine kinases.
S Lovera
UCL (University College London), 2016
2016
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Articles 1–11