John LaCava
John LaCava
Group Leader, The European Research Institute for the Biology of Ageing (ERIBA)
Verified email at - Homepage
Cited by
Cited by
RNA degradation by the exosome is promoted by a nuclear polyadenylation complex
J LaCava, J Houseley, C Saveanu, E Petfalski, E Thompson, A Jacquier, ...
Cell 121 (5), 713-724, 2005
RNA-quality control by the exosome
J Houseley, J LaCava, D Tollervey
Nature reviews Molecular cell biology 7 (7), 529-539, 2006
The human cap-binding complex is functionally connected to the nuclear RNA exosome
PR Andersen, M Domanski, MS Kristiansen, H Storvall, E Ntini, ...
Nature structural & molecular biology 20 (12), 1367, 2013
Affinity proteomics reveals human host factors implicated in discrete stages of LINE-1 retrotransposition
MS Taylor, J LaCava, P Mita, KR Molloy, CRL Huang, D Li, EM Adney, ...
Cell 155 (5), 1034-1048, 2013
Rapid, optimized interactomic screening
Z Hakhverdyan, M Domanski, LE Hough, AA Oroskar, AR Oroskar, ...
Nature methods 12 (6), 553-560, 2015
Improved methodology for the affinity isolation of human protein complexes expressed at near endogenous levels
M Domanski, K Molloy, H Jiang, BT Chait, MP Rout, TH Jensen, J LaCava
Biotechniques, 1, 2012
Affinity proteomics to study endogenous protein complexes: pointers, pitfalls, preferences and perspectives
J LaCava, KR Molloy, MS Taylor, M Domanski, BT Chait, MP Rout
Biotechniques 58 (3), 103-119, 2015
LINE-1 protein localization and functional dynamics during the cell cycle
P Mita, A Wudzinska, X Sun, J Andrade, S Nayak, DJ Kahler, S Badri, ...
Elife 7, e30058, 2018
Dissection of affinity captured LINE-1 macromolecular complexes
MS Taylor, I Altukhov, KR Molloy, P Mita, H Jiang, EM Adney, ...
Elife 7, e30094, 2018
Expression and detection of LINE-1 ORF-encoded proteins
L Dai, J LaCava, MS Taylor, JD Boeke
Mobile genetic elements 4 (3), 1034-48, 2014
Polycomb complexes associate with enhancers and promote oncogenic transcriptional programs in cancer through multiple mechanisms
HL Chan, F Beckedorff, Y Zhang, J Garcia-Huidobro, H Jiang, A Colaprico, ...
Nature communications 9 (1), 1-16, 2018
Targeting the CALR interactome in myeloproliferative neoplasms
E Pronier, P Cifani, TR Merlinsky, KB Berman, AVH Somasundara, ...
JCI insight 3 (22), 2018
The Polycomb group protein CBX6 is an essential regulator of embryonic stem cell identity
A Santanach, E Blanco, H Jiang, KR Molloy, M Sansó, J LaCava, L Morey, ...
Nature communications 8 (1), 1-11, 2017
Characterizing ZC3H18, a multi-domain protein at the interface of RNA production and destruction decisions
K Winczura, M Schmid, C Iasillo, KR Molloy, LM Harder, JS Andersen, ...
Cell reports 22 (1), 44-58, 2018
Protein complex affinity capture from cryomilled mammalian cells
J LaCava, H Jiang, MP Rout
JoVE (Journal of Visualized Experiments), e54518, 2016
Protein complex purification by affinity capture
J LaCava, J Fernandez-Martinez, Z Hakhverdyan, MP Rout
Cold Spring Harbor Protocols 2016 (7), pdb. top077545, 2016
Purification and analysis of endogenous human RNA exosome complexes
M Domanski, P Upla, WJ Rice, KR Molloy, NE Ketaren, DL Stokes, ...
Rna 22 (9), 1467-1475, 2016
Characterization of L1-Ribonucleoprotein particles
MS Taylor, J LaCava, L Dai, P Mita, KH Burns, MP Rout, JD Boeke
Transposons and Retrotransposons, 311-338, 2016
Improved native isolation of endogenous Protein A-tagged protein complexes
J LaCava, N Chandramouli, H Jiang, MP Rout
Biotechniques 54 (4), 213-216, 2013
Optimized affinity capture of yeast protein complexes
J LaCava, J Fernandez-Martinez, Z Hakhverdyan, MP Rout
Cold Spring Harbor Protocols 2016 (7), pdb. prot087932, 2016
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