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Jonas J Neher
Jonas J Neher
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Microglial phagocytosis of live neurons
GC Brown, JJ Neher
Nature Reviews Neuroscience 15 (4), 209-216, 2014
8752014
Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota
T Harach, N Marungruang, N Duthilleul, V Cheatham, KD Mc Coy, ...
Scientific reports 7 (1), 41802, 2017
7482017
Innate immune memory in the brain shapes neurological disease hallmarks
AC Wendeln, K Degenhardt, L Kaurani, M Gertig, T Ulas, G Jain, ...
Nature 556 (7701), 332-338, 2018
7352018
Inflammatory neurodegeneration and mechanisms of microglial killing of neurons
GC Brown, JJ Neher
Molecular neurobiology 41, 242-247, 2010
6302010
Microglia states and nomenclature: A field at its crossroads
RC Paolicelli, A Sierra, B Stevens, ME Tremblay, A Aguzzi, B Ajami, I Amit, ...
Neuron 110 (21), 3458-3483, 2022
5392022
Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE
S Parhizkar, T Arzberger, M Brendel, G Kleinberger, M Deussing, C Focke, ...
Nature neuroscience 22 (2), 191-204, 2019
4422019
Inhibition of microglial phagocytosis is sufficient to prevent inflammatory neuronal death
JJ Neher, U Neniskyte, JW Zhao, A Bal-Price, AM Tolkovsky, GC Brown
The Journal of Immunology 186 (8), 4973-4983, 2011
4342011
Eaten alive! Cell death by primary phagocytosis:‘phagoptosis’
GC Brown, JJ Neher
Trends in biochemical sciences 37 (8), 325-332, 2012
3642012
Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging
P Füger, JK Hefendehl, K Veeraraghavalu, AC Wendeln, C Schlosser, ...
Nature neuroscience 20 (10), 1371-1376, 2017
3472017
Phagocytosis executes delayed neuronal death after focal brain ischemia
JJ Neher, JV Emmrich, M Fricker, PK Mander, C Théry, GC Brown
Proceedings of the National Academy of Sciences 110 (43), E4098-E4107, 2013
3442013
Homeostatic and injury‐induced microglia behavior in the aging brain
JK Hefendehl, JJ Neher, RB Sühs, S Kohsaka, A Skodras, M Jucker
Aging cell 13 (1), 60-69, 2014
3302014
Infiltrating monocytes promote brain inflammation and exacerbate neuronal damage after status epilepticus
NH Varvel, JJ Neher, A Bosch, W Wang, RM Ransohoff, RJ Miller, ...
Proceedings of the National Academy of Sciences 113 (38), E5665-E5674, 2016
3152016
Neuronal death induced by nanomolar amyloid β is mediated by primary phagocytosis of neurons by microglia
U Neniskyte, JJ Neher, GC Brown
Journal of Biological Chemistry 286 (46), 39904-39913, 2011
2372011
MFG-E8 mediates primary phagocytosis of viable neurons during neuroinflammation
M Fricker, JJ Neher, JW Zhao, C Théry, AM Tolkovsky, GC Brown
Journal of Neuroscience 32 (8), 2657-2666, 2012
2252012
Priming microglia for innate immune memory in the brain
JJ Neher, C Cunningham
Trends in Immunology 40 (4), 358-374, 2019
1752019
Primary phagocytosis of neurons by inflamed microglia: potential roles in neurodegeneration
JJ Neher, U Neniskyte, GC Brown
Frontiers in pharmacology 3, 19364, 2012
1672012
Inhibition of UDP/P2Y6 purinergic signaling prevents phagocytosis of viable neurons by activated microglia in vitro and in vivo
JJ Neher, U Neniskyte, T Hornik, GC Brown
Glia 62 (9), 1463-1475, 2014
1382014
Inflammatory mechanisms in neurodegeneration
MR Nichols, MK St‐Pierre, AC Wendeln, NJ Makoni, LK Gouwens, ...
Journal of neurochemistry 149 (5), 562-581, 2019
1062019
Rotenone induces neuronal death by microglial phagocytosis of neurons
JV Emmrich, TC Hornik, JJ Neher, GC Brown
The FEBS journal 280 (20), 5030-5038, 2013
1042013
Replacement of brain-resident myeloid cells does not alter cerebral amyloid-β deposition in mouse models of Alzheimer’s disease
NH Varvel, SA Grathwohl, K Degenhardt, C Resch, A Bosch, M Jucker, ...
Journal of Experimental Medicine 212 (11), 1803-1809, 2015
922015
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