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Michael Spiotto
Michael Spiotto
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PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8+ T cells
C Blank, I Brown, AC Peterson, M Spiotto, Y Iwai, T Honjo, TF Gajewski
Cancer research 64 (3), 1140-1145, 2004
10242004
Low-dose X-ray radiotherapy–radiodynamic therapy via nanoscale metal–organic frameworks enhances checkpoint blockade immunotherapy
K Lu, C He, N Guo, C Chan, K Ni, G Lan, H Tang, C Pelizzari, YX Fu, ...
Nature biomedical engineering 2 (8), 600-610, 2018
4442018
Induced sensitization of tumor stroma leads to eradication of established cancer by T cells
B Zhang, NA Bowerman, JK Salama, H Schmidt, MT Spiotto, ...
The Journal of experimental medicine 204 (1), 49-55, 2007
4032007
Bystander elimination of antigen loss variants in established tumors
MT Spiotto, DA Rowley, H Schreiber
Nature medicine 10 (3), 294-298, 2004
3122004
Increasing tumor antigen expression overcomes “ignorance” to solid tumors via crosspresentation by bone marrow-derived stromal cells
MT Spiotto, P Yu, DA Rowley, MI Nishimura, SC Meredith, TF Gajewski, ...
Immunity 17 (6), 737-747, 2002
3112002
Characterization of the role of IL‐6 in the progression of prostate cancer
TDK Chung, JJ Yu, MT Spiotto, M Bartkowski, JW Simons
The Prostate 38 (3), 199-207, 1999
2901999
STAT3 mediates IL‐6‐induced neuroendocrine differentiation in prostate cancer cells
MT Spiotto, TDK Chung
The Prostate 42 (3), 186-195, 2000
2132000
STAT3 mediates IL‐6‐induced growth inhibition in the human prostate cancer cell line LNCaP
MT Spiotto, TDK Chung
The Prostate 42 (2), 88-98, 2000
1802000
The intersection of radiotherapy and immunotherapy: mechanisms and clinical implications
M Spiotto, YX Fu, RR Weichselbaum
Science immunology 1 (3), eaag1266-eaag1266, 2016
1682016
Radiotherapy after prostatectomy: improved biochemical relapse-free survival with whole pelvic compared with prostate bed only for high-risk patients
MT Spiotto, SL Hancock, CR King
International Journal of Radiation Oncology* Biology* Physics 69 (1), 54-61, 2007
1682007
Preferential cytotoxicity of bortezomib toward hypoxic tumor cells via overactivation of endoplasmic reticulum stress pathways
DR Fels, J Ye, AT Segan, SJ Kridel, M Spiotto, M Olson, AC Koong, ...
Cancer research 68 (22), 9323-9330, 2008
1642008
Improved outcomes with higher doses for salvage radiotherapy after prostatectomy
CR King, MT Spiotto
International Journal of Radiation Oncology* Biology* Physics 71 (1), 23-27, 2008
1462008
Interleukin‐6 activates phosphatidylinositol‐3 kinase, which inhibits apoptosis in human prostate cancer cell lines
TDK Chung, JJ Yu, TA Kong, MT Spiotto, JM Lin
The Prostate 42 (1), 1-7, 2000
1382000
Complementary Role of CD4+ T Cells and Secondary Lymphoid Tissues for Cross-presentation of Tumor Antigen to CD8+ T Cells
P Yu, MT Spiotto, Y Lee, H Schreiber, YX Fu
The Journal of experimental medicine 197 (8), 985-995, 2003
1172003
Imaging the unfolded protein response in primary tumors reveals microenvironments with metabolic variations that predict tumor growth
MT Spiotto, A Banh, I Papandreou, H Cao, MG Galvez, GC Gurtner, ...
Cancer research 70 (1), 78-88, 2010
1052010
Machine learning–guided adjuvant treatment of head and neck cancer
FM Howard, S Kochanny, M Koshy, M Spiotto, AT Pearson
JAMA network open 3 (11), e2025881-e2025881, 2020
902020
Response-adapted volume de-escalation (RAVD) in locally advanced head and neck cancer
VM Villaflor, JM Melotek, TG Karrison, RJ Brisson, EA Blair, L Portugal, ...
Annals of Oncology 27 (5), 908-913, 2016
852016
Rapid destruction of the tumor microenvironment by CTLs recognizing cancer-specific antigens cross-presented by stromal cells
MT Spiotto, H Schreiber
Cancer immunity 5 (1), 2005
812005
Differences in survival with surgery and postoperative radiotherapy compared with definitive chemoradiotherapy for oral cavity cancer: a national cancer database analysis
MT Spiotto, G Jefferson, B Wenig, M Markiewicz, RR Weichselbaum, ...
JAMA Otolaryngology–Head & Neck Surgery 143 (7), 691-699, 2017
732017
Combination of radiotherapy and vaccination overcomes checkpoint blockade resistance
W Zheng, KB Skowron, JP Namm, B Burnette, C Fernandez, A Arina, ...
Oncotarget 7 (28), 43039, 2016
722016
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