Jackson Cahn
Jackson Cahn
Bestätigte E-Mail-Adresse bei ethz.ch
Titel
Zitiert von
Zitiert von
Jahr
General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH
S Brinkmann-Chen, T Flock, JKB Cahn, CD Snow, EM Brustad, ...
Proceedings of the National Academy of Sciences 110 (27), 10946-10951, 2013
782013
A general tool for engineering the NAD/NADP cofactor preference of oxidoreductases
JKB Cahn, CA Werlang, A Baumschlager, S Brinkmann-Chen, SL Mayo, ...
ACS synthetic biology 6 (2), 326-333, 2017
642017
Discovery of a regioselectivity switch in nitrating P450s guided by molecular dynamics simulations and Markov models
SC Dodani, G Kiss, JKB Cahn, Y Su, VS Pande, FH Arnold
Nature chemistry 8 (5), 419-425, 2016
632016
Directed evolution of a bright near-infrared fluorescent rhodopsin using a synthetic chromophore
L Herwig, AJ Rice, CN Bedbrook, RK Zhang, A Lignell, JKB Cahn, ...
Cell chemical biology 24 (3), 415-425, 2017
392017
Directed evolution mimics allosteric activation by stepwise tuning of the conformational ensemble
AR Buller, P Van Roye, JKB Cahn, RA Scheele, M Herger, FH Arnold
Journal of the American Chemical Society 140 (23), 7256-7266, 2018
332018
The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography
H Marshall, M Venkat, NS Hti Lar Seng, J Cahn, DH Juers
Acta Crystallographica Section D: Biological Crystallography 68 (1), 69-81, 2012
322012
Structural, functional, and spectroscopic characterization of the substrate scope of the novel nitrating cytochrome P450 TxtE
SC Dodani, JKB Cahn, T Heinisch, S Brinkmann‐Chen, JA McIntosh, ...
ChemBioChem 15 (15), 2259-2267, 2014
302014
Mutations in adenine-binding pockets enhance catalytic properties of NAD (P) H-dependent enzymes
JKB Cahn, A Baumschlager, S Brinkmann-Chen, FH Arnold
Protein Engineering Design and Selection 29 (1), 31-38, 2016
272016
Single-bacterial genomics validates rich and varied specialized metabolism of uncultivated Entotheonella sponge symbionts
T Mori, JKB Cahn, MC Wilson, RA Meoded, V Wiebach, AFC Martinez, ...
Proceedings of the National Academy of Sciences 115 (8), 1718-1723, 2018
252018
Cofactor specificity motifs and the induced fit mechanism in Class I ketol-acid reductoisomerases
JKB Cahn, S Brinkmann-Chen, T Spatzal, JA Wiig, AR Buller, O Einsle, ...
Biochemical Journal 468 (3), 475-484, 2015
192015
Uncovering rare NADH-preferring ketol-acid reductoisomerases
S Brinkmann-Chen, JKB Cahn, FH Arnold
Metabolic engineering 26, 17-22, 2014
182014
4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation
SA Lieblich, KY Fang, JKB Cahn, J Rawson, J LeBon, HT Ku, DA Tirrell
Journal of the American Chemical Society 139 (25), 8384-8387, 2017
172017
Cell adhesion to borate glasses by colloidal probe microscopy
SM Wiederhorn, YH Chae, CG Simon Jr, J Cahn, Y Deng, D Day
Acta biomaterialia 7 (5), 2256-2263, 2011
162011
The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order
DH Juers, CA Farley, CP Saxby, RA Cotter, JKB Cahn, RC Holton-Burke, ...
Acta Crystallographica Section D: Structural Biology 74 (9), 922-938, 2018
42018
Artificial domain duplication replicates evolutionary history of ketol‐acid reductoisomerases
JKB Cahn, S Brinkmann‐Chen, AR Buller, FH Arnold
Protein Science 25 (7), 1241-1248, 2015
32015
Characterization of an Orphan Type III Polyketide Synthase Conserved in Uncultivated “Entotheonella” Sponge Symbionts
S Reiter, JKB Cahn, V Wiebach, R Ueoka, J Piel
ChemBioChem 21 (4), 564-571, 2020
12020
Opening up the Single‐Cell Toolbox for Microbial Natural Products Research
J Cahn, J Piel
Angewandte Chemie International Edition, 2019
12019
Enzyme Nicotinamide Cofactor Specificity Reversal Guided by Automated Structural Analysis and Library Design
JKB Cahn, S Brinkmann-Chen, FH Arnold
Synthetic Metabolic Pathways, 15-26, 2018
12018
The Evolutionary Profile of a Superproducer Sponge Symbiont, Candidatus" Entheonella"
JKB Cahn, EE Peters, A Lotti, C Field, C Rückert, J Kalinowski, ...
MARINE DRUGS 18 (1), 2020
2020
Single-Bacterial Genomics, Raman Spectroscopy, and Biochemical Studies Identify Metabolic Functions of Uncultivated Marine Microbiota
F Hemmerling, M Kogawa, M Hosokawa, M Ando, T Mori, ...
MARINE DRUGS 18 (1), 2020
2020
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