| Tumor-derived hydrogen sulfide, produced by cystathionine-β-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer C Szabo, C Coletta, C Chao, K Módis, B Szczesny, A Papapetropoulos, ... Proceedings of the National Academy of Sciences 110 (30), 12474-12479, 2013 | 708 | 2013 |
| AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA … B Szczesny, K Módis, K Yanagi, C Coletta, S Le Trionnaire, A Perry, ... Nitric oxide 41, 120-130, 2014 | 275 | 2014 |
| Long patch base excision repair in mammalian mitochondrial genomes B Szczesny, AW Tann, MJ Longley, WC Copeland, S Mitra Journal of Biological Chemistry 283 (39), 26349-26356, 2008 | 188 | 2008 |
| Identification and characterization of mitochondrial abasic (AP)-endonuclease in mammalian cells R Chattopadhyay, L Wiederhold, B Szczesny, I Boldogh, TK Hazra, ... Nucleic acids research 34 (7), 2067-2076, 2006 | 186 | 2006 |
| Oxidative genome damage and its repair: implications in aging and neurodegenerative diseases ML Hegde, AK Mantha, TK Hazra, KK Bhakat, S Mitra, B Szczesny Mechanisms of ageing and development 133 (4), 157-168, 2012 | 169 | 2012 |
| Apoptosis induced by persistent single-strand breaks in mitochondrial genome: critical role of EXOG (5′-EXO/endonuclease) in their repair AW Tann, I Boldogh, G Meiss, W Qian, B Van Houten, S Mitra, B Szczesny Journal of Biological Chemistry 286 (37), 31975-31983, 2011 | 163 | 2011 |
| The synthesis and functional evaluation of a mitochondria-targeted hydrogen sulfide donor,(10-oxo-10-(4-(3-thioxo-3 H-1, 2-dithiol-5-yl) phenoxy) decyl) triphenylphosphonium … S Le Trionnaire, A Perry, B Szczesny, C Szabo, PG Winyard, ... MedChemComm 5 (6), 728-736, 2014 | 135 | 2014 |
| Age-dependent deficiency in import of mitochondrial DNA glycosylases required for repair of oxidatively damaged bases B Szczesny, TK Hazra, J Papaconstantinou, S Mitra, I Boldogh Proceedings of the National Academy of Sciences 100 (19), 10670-10675, 2003 | 135 | 2003 |
| Regulation of Vascular Tone, Angiogenesis and Cellular Bioenergetics by the 3-Mercaptopyruvate Sulfurtransferase/H2S Pathway: Functional Impairment by Hyperglycemia … C Coletta, K Módis, B Szczesny, A Brunyánszki, G Oláh, ECS Rios, ... Molecular Medicine 21, 1-14, 2015 | 133 | 2015 |
| AP39, a mitochondrially targeted hydrogen sulfide donor, exerts protective effects in renal epithelial cells subjected to oxidative stress in vitro and in acute renal injury in … A Ahmad, G Olah, B Szczesny, ME Wood, M Whiteman, C Szabo Shock 45 (1), 88-97, 2016 | 126 | 2016 |
| Mitochondrial DNA damage and subsequent activation of Z-DNA binding protein 1 links oxidative stress to inflammation in epithelial cells B Szczesny, M Marcatti, A Ahmad, M Montalbano, A Brunyánszki, SI Bibli, ... Scientific reports 8 (1), 914, 2018 | 122 | 2018 |
| Upregulation of cystathionine-β-synthase in colonic epithelia reprograms metabolism and promotes carcinogenesis CNM Phillips, JR Zatarain, ME Nicholls, C Porter, SG Widen, K Thanki, ... Cancer research 77 (21), 5741-5754, 2017 | 117 | 2017 |
| Intracellular trafficking and regulation of mammalian AP-endonuclease 1 (APE1), an essential DNA repair protein S Mitra, T Izumi, I Boldogh, KK Bhakat, R Chattopadhyay, B Szczesny DNA repair 6 (4), 461-469, 2007 | 116 | 2007 |
| Role of endogenous and exogenous nitric oxide, carbon monoxide and hydrogen sulfide in HCT116 colon cancer cell proliferation G Oláh, K Módis, G Törö, MR Hellmich, B Szczesny, C Szabo Biochemical pharmacology 149, 186-204, 2018 | 112 | 2018 |
| Effect of S-adenosyl-L-methionine (SAM), an allosteric activator of cystathionine-β-synthase (CBS) on colorectal cancer cell proliferation and bioenergetics in vitro K Módis, C Coletta, A Asimakopoulou, B Szczesny, C Chao, ... Nitric oxide 41, 146-156, 2014 | 104 | 2014 |
| Inhibition of hydrogen sulfide biosynthesis sensitizes lung adenocarcinoma to chemotherapeutic drugs by inhibiting mitochondrial DNA repair and suppressing cellular bioenergetics B Szczesny, M Marcatti, JR Zatarain, N Druzhyna, JE Wiktorowicz, P Nagy, ... Scientific reports 6 (1), 36125, 2016 | 100 | 2016 |
| Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes SE Tsutakawa, DS Shin, CD Mol, T Izumi, AS Arvai, AK Mantha, ... Journal of Biological Chemistry 288 (12), 8445-8455, 2013 | 99 | 2013 |
| Role of human DNA glycosylase Nei-like 2 (NEIL2) and single strand break repair protein polynucleotide kinase 3′-phosphatase in maintenance of mitochondrial genome SM Mandal, ML Hegde, A Chatterjee, PM Hegde, B Szczesny, D Banerjee, ... Journal of Biological Chemistry 287 (4), 2819-2829, 2012 | 98 | 2012 |
| Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: implications for the regulation of mitochondrial function B Szczesny, A Brunyanszki, G Olah, S Mitra, C Szabo Nucleic acids research 42 (21), 13161-13173, 2014 | 93 | 2014 |
| Suppression of somatic expansion delays the onset of pathophysiology in a mouse model of Huntington’s disease H Budworth, FR Harris, P Williams, DY Lee, A Holt, J Pahnke, B Szczesny, ... PLoS genetics 11 (8), e1005267, 2015 | 90 | 2015 |
