Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling SM Chambers, CA Fasano, EP Papapetrou, M Tomishima, M Sadelain, ... Nature biotechnology 27 (3), 275-280, 2009 | 3901 | 2009 |
Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs G Lee, EP Papapetrou, H Kim, SM Chambers, MJ Tomishima, CA Fasano, ... nature 461 (7262), 402-406, 2009 | 1116 | 2009 |
Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis JS Yang, T Maurin, N Robine, KD Rasmussen, KL Jeffrey, R Chandwani, ... Proceedings of the National Academy of Sciences 107 (34), 15163-15168, 2010 | 580 | 2010 |
Safe harbours for the integration of new DNA in the human genome M Sadelain, EP Papapetrou, FD Bushman Nature Reviews Cancer 12 (1), 51-58, 2012 | 549 | 2012 |
A bioinformatic assay for pluripotency in human cells FJ Müller, BM Schuldt, R Williams, D Mason, G Altun, EP Papapetrou, ... Nature methods 8 (4), 315-317, 2011 | 533 | 2011 |
Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation EP Papapetrou, MJ Tomishima, SM Chambers, Y Mica, E Reed, J Menon, ... Proceedings of the National Academy of Sciences 106 (31), 12759-12764, 2009 | 395 | 2009 |
Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells EP Papapetrou, G Lee, N Malani, M Setty, I Riviere, LMS Tirunagari, ... Nature biotechnology 29 (1), 73-78, 2011 | 371 | 2011 |
Gene insertion into genomic safe harbors for human gene therapy EP Papapetrou, A Schambach Molecular Therapy 24 (4), 678-684, 2016 | 249 | 2016 |
Therapeutic targeting of RNA splicing catalysis through inhibition of protein arginine methylation JY Fong, L Pignata, PA Goy, KC Kawabata, SCW Lee, CM Koh, D Musiani, ... Cancer cell 36 (2), 194-209. e9, 2019 | 212 | 2019 |
TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells N Verma, H Pan, LC Doré, A Shukla, QV Li, B Pelham-Webb, V Teijeiro, ... Nature genetics 50 (1), 83-95, 2018 | 172 | 2018 |
Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells AG Kotini, CJ Chang, I Boussaad, JJ Delrow, EK Dolezal, AB Nagulapally, ... Nature biotechnology 33 (6), 646-655, 2015 | 160 | 2015 |
Patient-derived induced pluripotent stem cells in cancer research and precision oncology EP Papapetrou Nature medicine 22 (12), 1392-1401, 2016 | 154 | 2016 |
miR-371-3 expression predicts neural differentiation propensity in human pluripotent stem cells H Kim, G Lee, Y Ganat, EP Papapetrou, I Lipchina, ND Socci, M Sadelain, ... Cell stem cell 8 (6), 695-706, 2011 | 151 | 2011 |
Stage-specific human induced pluripotent stem cells map the progression of myeloid transformation to transplantable leukemia AG Kotini, CJ Chang, A Chow, H Yuan, TC Ho, T Wang, S Vora, ... Cell stem cell 20 (3), 315-328. e7, 2017 | 142 | 2017 |
Gene transfer into human hematopoietic progenitor cells with an episomal vector carrying an S/MAR element EP Papapetrou, PG Ziros, ID Micheva, NC Zoumbos, A Athanassiadou Gene therapy 13 (1), 40-51, 2006 | 115 | 2006 |
A genetic strategy for single and combinatorial analysis of miRNA function in mammalian hematopoietic stem cells EP Papapetrou, JE Korkola, M Sadelain Stem cells 28 (2), 287-296, 2010 | 105 | 2010 |
Transcriptional activation by Oct4 is sufficient for the maintenance and induction of pluripotency F Hammachi, GM Morrison, AA Sharov, A Livigni, S Narayan, ... Cell reports 1 (2), 99-109, 2012 | 87 | 2012 |
Generation of transgene-free human induced pluripotent stem cells with an excisable single polycistronic vector EP Papapetrou, M Sadelain Nature protocols 6 (9), 1251-1273, 2011 | 86 | 2011 |
A method to sequence and quantify DNA integration for monitoring outcome in gene therapy T Brady, SL Roth, N Malani, GP Wang, CC Berry, P Leboulch, ... Nucleic acids research 39 (11), e72-e72, 2011 | 81 | 2011 |
Genetic modification of hematopoietic stem cells with nonviral systems: past progress and future prospects EP Papapetrou, NC Zoumbos, A Athanassiadou Gene therapy 12 (1), S118-S130, 2005 | 78 | 2005 |