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Michail Nomikos
Michail Nomikos
Qatar University, College of Medicine
Bestätigte E-Mail-Adresse bei qu.edu.qa - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Role of phospholipase C-ζ domains in Ca2+-dependent phosphatidylinositol 4, 5-bisphosphate hydrolysis and cytoplasmic Ca2+ oscillations
M Nomikos, LM Blayney, MG Larman, K Campbell, A Rossbach, ...
Journal of Biological Chemistry 280 (35), 31011-31018, 2005
1812005
Phospholipase Cζ rescues failed oocyte activation in a prototype of male factor infertility
M Nomikos, Y Yu, K Elgmati, M Theodoridou, K Campbell, ...
Fertility and sterility 99 (1), 76-85, 2013
1382013
Binding of phosphoinositide-specific phospholipase C-ζ (PLC-ζ) to phospholipid membranes: potential role of an unstructured cluster of basic residues
M Nomikos, A Mulgrew-Nesbitt, P Pallavi, G Mihalyne, I Zaitseva, ...
Journal of biological chemistry 282 (22), 16644-16653, 2007
1152007
Starting a new life: Sperm PLC‐zeta mobilizes the Ca2+ signal that induces egg activation and embryo development: An essential phospholipase C with …
M Nomikos, K Swann, FA Lai
Bioessays 34 (2), 126-134, 2012
1142012
PLCζ causes Ca2+ oscillations in mouse eggs by targeting intracellular and not plasma membrane PI(4,5)P2
Y Yu, M Nomikos, M Theodoridou, G Nounesis, FA Lai, K Swann
Molecular biology of the cell 23 (2), 371-380, 2012
972012
Sperm PLCζ: from structure to Ca2+ oscillations, egg activation and therapeutic potential
M Nomikos, J Kashir, K Swann, FA Lai
FEBS letters 587 (22), 3609-3616, 2013
922013
Sperm-induced Ca2+ release during egg activation in mammals
J Kashir, M Nomikos, FA Lai, K Swann
Biochemical and biophysical research communications 450 (3), 1204-1211, 2014
862014
Phospholipase Cζ binding to PtdIns(4,5)P2 requires the XY-linker region
M Nomikos, K Elgmati, M Theodoridou, BL Calver, G Nounesis, K Swann, ...
Journal of cell science 124 (15), 2582-2590, 2011
842011
Rescue of failed oocyte activation after ICSI in a mouse model of male factor infertility by recombinant phospholipase Cζ
R Sanusi, Y Yu, M Nomikos, FA Lai, K Swann
MHR: Basic science of reproductive medicine 21 (10), 783-791, 2015
832015
Sperm-specific post-acrosomal WW-domain binding protein (PAWP) does not cause Ca2+ release in mouse oocytes
M Nomikos, JR Sanders, M Theodoridou, J Kashir, E Matthews, ...
MHR: Basic science of reproductive medicine 20 (10), 938-947, 2014
792014
Phospholipase C-ζ-induced Ca2+ oscillations cause coincident cytoplasmic movements in human oocytes that failed to fertilize after intracytoplasmic sperm injection
K Swann, S Windsor, K Campbell, K Elgmati, M Nomikos, ...
Fertility and sterility 97 (3), 742-747, 2012
702012
Novel regulation of PLCζ activity via its XY-linker
M Nomikos, K Elgmati, M Theodoridou, A Georgilis, JR Gonzalez-Garcia, ...
Biochemical Journal 438 (3), 427-432, 2011
692011
Male infertility-linked point mutation disrupts the Ca2+ oscillation-inducing and PIP2 hydrolysis activity of sperm PLCζ
M Nomikos, K Elgmati, M Theodoridou, BL Calver, B Cumbes, ...
Biochemical Journal 434 (2), 211-217, 2011
692011
Essential role of sperm-specific PLC-zeta in egg activation and male factor infertility: an update
A Saleh, J Kashir, A Thanassoulas, B Safieh-Garabedian, FA Lai, ...
Frontiers in cell and developmental biology 8, 28, 2020
602020
Expression of sperm PLCζ and clinical outcomes of ICSI-AOA in men affected by globozoospermia due to DPY19L2 deletion
M Tavalaee, M Nomikos, FA Lai, MH Nasr-Esfahani
Reproductive biomedicine online 36 (3), 348-355, 2018
582018
Functional disparity between human PAWP and PLCζ in the generation of Ca2+ oscillations for oocyte activation
M Nomikos, JR Sanders, J Kashir, R Sanusi, L Buntwal, D Love, P Ashley, ...
MHR: Basic science of reproductive medicine 21 (9), 702-710, 2015
562015
The role and mechanism of action of sperm PLC-zeta in mammalian fertilisation
M Nomikos, J Kashir, FA Lai
Biochemical Journal 474 (21), 3659-3673, 2017
442017
Essential role of the EF-hand domain in targeting sperm phospholipase Cζ to membrane phosphatidylinositol 4, 5-bisphosphate (PIP2)
M Nomikos, JR Sanders, D Parthimos, L Buntwal, BL Calver, ...
Journal of Biological Chemistry 290 (49), 29519-29530, 2015
442015
Distinctive malfunctions of calmodulin mutations associated with heart RyR2-mediated arrhythmic disease
V Vassilakopoulou, BL Calver, A Thanassoulas, K Beck, H Hu, L Buntwal, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1850 (11), 2168-2176, 2015
442015
Antigen unmasking enhances visualization efficacy of the oocyte activation factor, phospholipase C zeta, in mammalian sperm
J Kashir, L Buntwal, M Nomikos, BL Calver, P Stamatiadis, P Ashley, ...
MHR: Basic science of reproductive medicine 23 (1), 54-67, 2017
432017
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