Human tRNA synthetase catalytic nulls with diverse functions WS Lo, E Gardiner, Z Xu, CF Lau, F Wang, JJ Zhou, JD Mendlein, ... Science 345 (6194), 328-332, 2014 | 130 | 2014 |
Compositions and methods comprising histidyl-tRNA synthetase splice variants having non-canonical biological activities J Zhou, CF Lau, XU Zhiwen, WS Lo, KH Piehl, LA Greene US Patent 8,404,242, 2013 | 99 | 2013 |
GABAA receptor subtype selectivity underlying anxiolytic effect of 6-hydroxyflavone L Ren, F Wang, Z Xu, WM Chan, C Zhao, H Xue Biochemical pharmacology 79 (9), 1337-1344, 2010 | 94 | 2010 |
GABAA receptor subtype selectivity underlying selective anxiolytic effect of baicalin F Wang, Z Xu, L Ren, SY Tsang, H Xue Neuropharmacology 55 (7), 1231-1237, 2008 | 84 | 2008 |
Compositions and methods comprising histidyl-TRNA synthetase splice variants having non-canonical biological activities J Zhou, CF Lau, XU Zhiwen, WS Lo, KH Piehl, LA Greene US Patent 8,753,638, 2014 | 74 | 2014 |
Two isoforms of GABAA receptor β2 subunit with different electrophysiological properties: differential expression and genotypical correlations in schizophrenia C Zhao, Z Xu, J Chen, Z Yu, KL Tong, WS Lo, FW Pun, SK Ng, SY Tsang, ... Molecular psychiatry 11 (12), 1092-1105, 2006 | 68 | 2006 |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-tRNA synthetases LA Greene, KP Chiang, F Hong, AP Vasserot, JD Watkins, CL Quinn, ... US Patent 8,945,541, 2015 | 66 | 2015 |
Structures of human histidyl-trna synthetase and methods of use XU Zhiwen, Z Wei, XL Yang, M Zhang, P Schimmel US Patent App. 13/948,982, 2014 | 64 | 2014 |
The Evolution of GABAA Receptor–Like Genes SY Tsang, SK Ng, Z Xu, H Xue Molecular biology and evolution 24 (2), 599-610, 2007 | 64 | 2007 |
Secreted histidyl-tRNA synthetase splice variants elaborate major epitopes for autoantibodies in inflammatory myositis JJ Zhou, F Wang, Z Xu, WS Lo, CF Lau, KP Chiang, LA Nangle, ... Journal of Biological Chemistry 289 (28), 19269-19275, 2014 | 59 | 2014 |
Internally deleted human tRNA synthetase suggests evolutionary pressure for repurposing Z Xu, Z Wei, JJ Zhou, F Ye, WS Lo, F Wang, CF Lau, J Wu, LA Nangle, ... Structure 20 (9), 1470-1477, 2012 | 56 | 2012 |
Anxiolytic-like effect of baicalin and its additivity with other anxiolytics Z Xu, F Wang, SY Tsang, KH Ho, H Zheng, CT Yuen, CY Chow, H Xue Planta medica 72 (02), 189-192, 2006 | 54 | 2006 |
Positive Selection within the Schizophrenia-Associated GABAA Receptor β2 Gene WS Lo, Z Xu, Z Yu, FW Pun, SK Ng, J Chen, KL Tong, C Zhao, X Xu, ... PLoS One 2 (5), e462, 2007 | 51 | 2007 |
Alternative-Splicing in the Exon-10 Region of GABAA Receptor β2 Subunit Gene: Relationships between Novel Isoforms and Psychotic Disorders C Zhao, Z Xu, F Wang, J Chen, SK Ng, PW Wong, Z Yu, FW Pun, L Ren, ... PloS one 4 (9), e6977, 2009 | 47 | 2009 |
Bi-allelic mutations in Phe-tRNA synthetase associated with a multi-system pulmonary disease support non-translational function Z Xu, WS Lo, DB Beck, LA Schuch, M Oláhová, R Kopajtich, YE Chong, ... The American Journal of Human Genetics 103 (1), 100-114, 2018 | 43 | 2018 |
Biallelic mutations in valyl-tRNA synthetase gene VARS are associated with a progressive neurodevelopmental epileptic encephalopathy J Friedman, DE Smith, MY Issa, V Stanley, R Wang, MI Mendes, ... Nature communications 10 (1), 707, 2019 | 38 | 2019 |
Serum-circulating His-tRNA synthetase inhibits organ-targeted immune responses RA Adams, C Fernandes-Cerqueira, A Notarnicola, E Mertsching, Z Xu, ... Cellular & molecular immunology 18 (6), 1463-1475, 2021 | 37 | 2021 |
Structural basis for homeodomain recognition by the cell-cycle regulator Geminin B Zhou, C Liu, Z Xu, G Zhu Proceedings of the National Academy of Sciences 109 (23), 8931-8936, 2012 | 32 | 2012 |
6, 2′-Dihydroxyflavone, a subtype-selective partial inverse agonist of GABAA receptor benzodiazepine site F Wang, Z Xu, CT Yuen, CY Chow, YL Lui, SY Tsang, H Xue Neuropharmacology 53 (4), 574-582, 2007 | 30 | 2007 |
A recombination hotspot in a schizophrenia-associated region of GABRB2 SK Ng, WS Lo, FW Pun, C Zhao, Z Yu, J Chen, KL Tong, Z Xu, SY Tsang, ... PloS one 5 (3), e9547, 2010 | 29 | 2010 |