| Evaluation of tunable diode laser absorption spectroscopy for in‐process water vapor mass flux measurements during freeze drying H Gieseler, WJ Kessler, M Finson, SJ Davis, PA Mulhall, V Bons, DJ Debo, ... Journal of Pharmaceutical Sciences 96 (7), 1776-1793, 2007 | 186 | 2007 |
| Freeze-dry microscopy of protein/sugar mixtures: drying behavior, interpretation of collapse temperatures and a comparison to corresponding glass transition data E Meister, H Gieseler Journal of pharmaceutical sciences 98 (9), 3072-3087, 2009 | 141 | 2009 |
| Freeze-drying of nanosuspensions, 1: freezing rate versus formulation design as critical factors to preserve the original particle size distribution J Beirowski, S Inghelbrecht, A Arien, H Gieseler Journal of pharmaceutical sciences 100 (5), 1958-1968, 2011 | 110 | 2011 |
| Evaluation of a new wireless temperature remote interrogation system (TEMPRIS) to measure product temperature during freeze drying S Schneid, H Gieseler Aaps PharmSciTech 9, 729-739, 2008 | 108 | 2008 |
| Use of manometric temperature measurement (MTM) and SMART™ freeze dryer technology for development of an optimized freeze‐drying cycle H Gieseler, T Kramer, MJ Pikal Journal of Pharmaceutical Sciences 96 (12), 3402-3418, 2007 | 91 | 2007 |
| Impact of payload hydrophobicity on the stability of antibody–drug conjugates JW Buecheler, M Winzer, J Tonillo, C Weber, H Gieseler Molecular pharmaceutics 15 (7), 2656-2664, 2018 | 84 | 2018 |
| Non-invasive product temperature determination during primary drying using tunable diode laser absorption spectroscopy SC Schneid, H Gieseler, WJ Kessler, MJ Pikal Journal of pharmaceutical sciences 98 (9), 3406-3418, 2009 | 84 | 2009 |
| Optimization of the secondary drying step in freeze drying using TDLAS technology SC Schneid, H Gieseler, WJ Kessler, SA Luthra, MJ Pikal Aaps Pharmscitech 12, 379-387, 2011 | 78 | 2011 |
| The effect of mannitol crystallization in mannitol–sucrose systems on LDH stability during freeze-drying A Al-Hussein, H Gieseler Journal of pharmaceutical sciences 101 (7), 2534-2544, 2012 | 59 | 2012 |
| Use of manometric temperature measurements (MTM) to characterize the freeze-drying behavior of amorphous protein formulations RE Johnson, ME Oldroyd, SS Ahmed, H Gieseler, LM Lewis Journal of pharmaceutical sciences 99 (6), 2863-2873, 2010 | 57 | 2010 |
| Freeze drying of nanosuspensions, 2: The role of the critical formulation temperature on stability of drug nanosuspensions and its practical implication on process design J Beirowski, S Inghelbrecht, A Arien, H Gieseler Journal of pharmaceutical sciences 100 (10), 4471-4481, 2011 | 51 | 2011 |
| Freeze drying of l-arginine/sucrose-based protein formulations, part I: influence of formulation and arginine counter ion on the critical formulation temperature, product … P Stärtzel, H Gieseler, M Gieseler, AM Abdul-Fattah, M Adler, HC Mahler, ... Journal of pharmaceutical sciences 104 (7), 2345-2358, 2015 | 50 | 2015 |
| Vial freeze-drying, part 1: new insights into heat transfer characteristics of tubing and molded vials S Hibler, C Wagner, H Gieseler Journal of pharmaceutical sciences 101 (3), 1189-1201, 2012 | 50 | 2012 |
| Investigation of histidine stabilizing effects on LDH during freeze-drying A Al-Hussein, H Gieseler Journal of pharmaceutical sciences 102 (3), 813-826, 2013 | 49 | 2013 |
| Predicting critical micelle concentration and micelle molecular weight of polysorbate 80 using compendial methods AC Braun, D Ilko, B Merget, H Gieseler, O Germershaus, U Holzgrabe, ... European Journal of Pharmaceutics and Biopharmaceutics 94, 559-568, 2015 | 46 | 2015 |
| Freeze-dry microscopy: impact of nucleation temperature and excipient concentration on collapse temperature data E Meister, S Šaši, H Gieseler Aaps Pharmscitech 10, 582-588, 2009 | 42 | 2009 |
| Freeze-drying of nanosuspensions, part 3: investigation of factors compromising storage stability of highly concentrated drug nanosuspensions J Beirowski, S Inghelbrecht, A Arien, H Gieseler Journal of pharmaceutical sciences 101 (1), 354-362, 2012 | 40 | 2012 |
| Taste masking of naproxen sodium granules by fluid-bed coating U Stange, C Führling, H Gieseler Pharmaceutical development and technology 19 (2), 137-147, 2014 | 38 | 2014 |
| Alteration of physicochemical properties for antibody-drug conjugates and their impact on stability JW Buecheler, M Winzer, C Weber, H Gieseler Journal of Pharmaceutical Sciences 109 (1), 161-168, 2020 | 37 | 2020 |
| Freeze-drying of L-arginine/sucrose-based protein formulations, Part 2: optimization of formulation design and freeze-drying process conditions for an L-arginine chloride-based … P Stärtzel, H Gieseler, M Gieseler, AM Abdul-Fattah, M Adler, HC Mahler, ... Journal of pharmaceutical sciences 104 (12), 4241-4256, 2015 | 37 | 2015 |
