Maritoclax and dinaciclib inhibit MCL-1 activity and induce apoptosis in both a MCL-1-dependent and-independent manner S Varadarajan, P Poornima, M Milani, K Gowda, S Amin, HG Wang, ... Oncotarget 6 (14), 12668, 2015 | 42 | 2015 |
BH3-only proteins are dispensable for apoptosis induced by pharmacological inhibition of both MCL-1 and BCL-X L G Greaves, M Milani, M Butterworth, RJ Carter, DP Byrne, PA Eyers, ... Cell Death & Differentiation 26 (6), 1037-1047, 2019 | 25 | 2019 |
DRP-1 is required for BH3 mimetic-mediated mitochondrial fragmentation and apoptosis M Milani, DP Byrne, G Greaves, M Butterworth, GM Cohen, PA Eyers, ... Cell death & disease 8 (1), e2552-e2552, 2018 | 25 | 2018 |
High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-X L in chronic myeloid leukemia CM Lucas, M Milani, M Butterworth, N Carmell, LJ Scott, RE Clark, ... Leukemia 30 (6), 1273-1281, 2016 | 24 | 2016 |
Karyotypic data detect interpopulational variation in Physalaemus olfersii and the first case of a supernumerary chromosome in the genus M Milani, CS Cassini, SM Recco-Pimentel, LB Lourenço Animal Biology Journal 2, 21-28, 2010 | 15 | 2010 |
Targeting intermediary metabolism enhances the efficacy of BH3 mimetic therapy in hematologic malignancies A Al-Zebeeby, M Vogler, M Milani, C Richards, A Alotibi, G Greaves, ... haematologica 104 (5), 1016, 2019 | 11 | 2019 |
Plasma Hsp90 level as a marker of early acute lymphoblastic leukemia engraftment and progression in mice M Milani, ABA Laranjeira, JF de Vasconcellos, SR Brandalise, AE Nowill, ... PloS one 10 (6), e0129298, 2015 | 8 | 2015 |
Exploring the potential of BH3 mimetic therapy in squamous cell carcinoma of the head and neck RJ Carter, M Milani, M Butterworth, A Alotibi, N Harper, G Yedida, ... Cell death & disease 10 (12), 1-10, 2019 | 3 | 2019 |
DRP-1 functions independently of mitochondrial structural perturbations to facilitate BH3 mimetic-mediated apoptosis M Milani, AJ Beckett, A Al-Zebeeby, X Luo, IA Prior, GM Cohen, ... Cell death discovery 5 (1), 1-11, 2019 | 3 | 2019 |
Apogossypol-mediated reorganisation of the endoplasmic reticulum antagonises mitochondrial fission and apoptosis G Yedida, M Milani, GM Cohen, S Varadarajan Cell death & disease 10 (7), 1-11, 2019 | 1 | 2019 |
PO-061 BCL-2 family of proteins, BCL-XL and MCL-1, regulate apoptosis and cancer cell survival by different mechanisms G Greaves, M Milani, D Byrne, R Carter, M Butterworth, X Luo, P Eyers, ... ESMO Open 3 (Suppl 2), A44-A45, 2018 | 1 | 2018 |
ER shaping proteins regulate mitochondrial fission, outer membrane permeabilization and apoptosis M Milani, GM Cohen, S Varadarajan BioRxiv, 340448, 2018 | 1 | 2018 |
Exploring the therapeutic potential and cellular mechanisms of BH3 mimetic-mediated apoptosis in cancer M Milani University of Liverpool, 2019 | | 2019 |
High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-XL in chronic myeloid leukemia. Leukemia C Lucas, M Milani, M Butterworth, N Carmell, L Scott, R Clark, G Cohen, ... Nature, 2016 | | 2016 |
BH3-only proteins are dispensable for apoptosis induced by the simultaneous inhibition of both MCL-1 and BCL-XL G Greaves, M Milani, M Butterworth, RJ Carter, DP Byrne, PA Eyers, ... | | |