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Tomohito Higashi
Tomohito Higashi
Fukushima Medical University
Dirección de correo verificada de fmu.ac.jp
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LSR defines cell corners for tricellular tight junction formation in epithelial cells
S Masuda, Y Oda, H Sasaki, J Ikenouchi, T Higashi, M Akashi, E Nishi, ...
Journal of cell science 124 (4), 548-555, 2011
2572011
Munc13-4 is a GTP-Rab27-binding protein regulating dense core granule secretion in platelets
R Shirakawa, T Higashi, A Tabuchi, A Yoshioka, H Nishioka, M Fukuda, ...
Journal of Biological Chemistry 279 (11), 10730-10737, 2004
2532004
Analysis of the ‘angulin’proteins LSR, ILDR1 and ILDR2–tricellulin recruitment, epithelial barrier function and implication in deafness pathogenesis
T Higashi, S Tokuda, S Kitajiri, S Masuda, H Nakamura, Y Oda, M Furuse
Journal of cell science 126 (4), 966-977, 2013
2392013
Maintenance of the epithelial barrier and remodeling of cell-cell junctions during cytokinesis
T Higashi, TR Arnold, RE Stephenson, KM Dinshaw, AL Miller
Current biology 26 (14), 1829-1842, 2016
1332016
Molecular organization of tricellular tight junctions
M Furuse, Y Izumi, Y Oda, T Higashi, N Iwamoto
Tissue barriers 2 (3), e28960, 2014
1302014
Tricellular junctions: how to build junctions at the TRICkiest points of epithelial cells
T Higashi, AL Miller
Molecular biology of the cell 28 (15), 2023-2034, 2017
1202017
Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases
R Shirakawa, S Fukai, M Kawato, T Higashi, H Kondo, T Ikeda, ...
Journal of Biological Chemistry 284 (32), 21580-21588, 2009
932009
ZO-1 knockout by TALEN-mediated gene targeting in MDCK cells: involvement of ZO-1 in the regulation of cytoskeleton and cell shape
S Tokuda, T Higashi, M Furuse
PloS one 9 (8), e104994, 2014
922014
Localization of angulin-1/LSR and tricellulin at tricellular contacts of brain and retinal endothelial cells in vivo
N Iwamoto, T Higashi, M Furuse
Cell structure and function 39 (1), 1-8, 2014
902014
Occludin and tricellulin facilitate formation of anastomosing tight-junction strand network to improve barrier function
AC Saito, T Higashi, Y Fukazawa, T Otani, M Tauchi, AY Higashi, ...
Molecular biology of the cell 32 (8), 722-738, 2021
772021
Rho flares repair local tight junction leaks
RE Stephenson, T Higashi, IS Erofeev, TR Arnold, M Leda, AB Goryachev, ...
Developmental cell 48 (4), 445-459. e5, 2019
772019
Biochemical characterization of the Rho GTPase-regulated actin assembly by diaphanous-related formins, mDia1 and Daam1, in platelets
T Higashi, T Ikeda, R Shirakawa, H Kondo, M Kawato, M Horiguchi, ...
Journal of biological chemistry 283 (13), 8746-8755, 2008
732008
Crystal structure of human DAAM1 formin homology 2 domain
M Yamashita, T Higashi, S Suetsugu, Y Sato, T Ikeda, R Shirakawa, T Kita, ...
Genes to cells 12 (11), 1255-1265, 2007
652007
Identification of protein kinase Cα as an essential, but not sufficient, cytosolic factor for Ca2+-induced α-and dense-core granule secretion in platelets
A Yoshioka, R Shirakawa, H Nishioka, A Tabuchi, T Higashi, H Ozaki, ...
Journal of Biological Chemistry 276 (42), 39379-39385, 2001
652001
Direct demonstration of involvement of protein kinase Cα in the Ca2+-induced platelet aggregation
A Tabuchi, A Yoshioka, T Higashi, R Shirakawa, H Nishioka, T Kita, ...
Journal of Biological Chemistry 278 (29), 26374-26379, 2003
612003
Constitutive GDP/GTP exchange and secretion-dependent GTP hydrolysis activity for Rab27 in platelets
H Kondo, R Shirakawa, T Higashi, M Kawato, M Fukuda, T Kita, ...
Journal of biological chemistry 281 (39), 28657-28665, 2006
602006
Flightless-I (Fli-I) regulates the actin assembly activity of diaphanous-related formins (DRFs) Daam1 and mDia1 in cooperation with active Rho GTPase
T Higashi, T Ikeda, T Murakami, R Shirakawa, M Kawato, K Okawa, ...
Journal of biological chemistry 285 (21), 16231-16238, 2010
592010
Regulation of platelet dense granule secretion by the Ral GTPase-exocyst pathway
M Kawato, R Shirakawa, H Kondo, T Higashi, T Ikeda, K Okawa, S Fukai, ...
Journal of biological chemistry 283 (1), 166-174, 2008
552008
A coronary artery disease-associated gene product, JCAD/KIAA1462, is a novel component of endothelial cell–cell junctions
M Akashi, T Higashi, S Masuda, T Komori, M Furuse
Biochemical and biophysical research communications 413 (2), 224-229, 2011
502011
MgcRacGAP restricts active RhoA at the cytokinetic furrow and both RhoA and Rac1 at cell–cell junctions in epithelial cells
EB Breznau, AC Semack, T Higashi, AL Miller
Molecular biology of the cell 26 (13), 2439-2455, 2015
482015
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Artículos 1–20