LSR defines cell corners for tricellular tight junction formation in epithelial cells S Masuda, Y Oda, H Sasaki, J Ikenouchi, T Higashi, M Akashi, E Nishi, ... Journal of cell science 124 (4), 548-555, 2011 | 257 | 2011 |
Munc13-4 is a GTP-Rab27-binding protein regulating dense core granule secretion in platelets R Shirakawa, T Higashi, A Tabuchi, A Yoshioka, H Nishioka, M Fukuda, ... Journal of Biological Chemistry 279 (11), 10730-10737, 2004 | 253 | 2004 |
Analysis of the ‘angulin’proteins LSR, ILDR1 and ILDR2–tricellulin recruitment, epithelial barrier function and implication in deafness pathogenesis T Higashi, S Tokuda, S Kitajiri, S Masuda, H Nakamura, Y Oda, M Furuse Journal of cell science 126 (4), 966-977, 2013 | 239 | 2013 |
Maintenance of the epithelial barrier and remodeling of cell-cell junctions during cytokinesis T Higashi, TR Arnold, RE Stephenson, KM Dinshaw, AL Miller Current biology 26 (14), 1829-1842, 2016 | 133 | 2016 |
Molecular organization of tricellular tight junctions M Furuse, Y Izumi, Y Oda, T Higashi, N Iwamoto Tissue barriers 2 (3), e28960, 2014 | 130 | 2014 |
Tricellular junctions: how to build junctions at the TRICkiest points of epithelial cells T Higashi, AL Miller Molecular biology of the cell 28 (15), 2023-2034, 2017 | 120 | 2017 |
Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases R Shirakawa, S Fukai, M Kawato, T Higashi, H Kondo, T Ikeda, ... Journal of Biological Chemistry 284 (32), 21580-21588, 2009 | 93 | 2009 |
ZO-1 knockout by TALEN-mediated gene targeting in MDCK cells: involvement of ZO-1 in the regulation of cytoskeleton and cell shape S Tokuda, T Higashi, M Furuse PloS one 9 (8), e104994, 2014 | 92 | 2014 |
Localization of angulin-1/LSR and tricellulin at tricellular contacts of brain and retinal endothelial cells in vivo N Iwamoto, T Higashi, M Furuse Cell structure and function 39 (1), 1-8, 2014 | 90 | 2014 |
Occludin and tricellulin facilitate formation of anastomosing tight-junction strand network to improve barrier function AC Saito, T Higashi, Y Fukazawa, T Otani, M Tauchi, AY Higashi, ... Molecular biology of the cell 32 (8), 722-738, 2021 | 77 | 2021 |
Rho flares repair local tight junction leaks RE Stephenson, T Higashi, IS Erofeev, TR Arnold, M Leda, AB Goryachev, ... Developmental cell 48 (4), 445-459. e5, 2019 | 77 | 2019 |
Biochemical characterization of the Rho GTPase-regulated actin assembly by diaphanous-related formins, mDia1 and Daam1, in platelets T Higashi, T Ikeda, R Shirakawa, H Kondo, M Kawato, M Horiguchi, ... Journal of biological chemistry 283 (13), 8746-8755, 2008 | 73 | 2008 |
Crystal structure of human DAAM1 formin homology 2 domain M Yamashita, T Higashi, S Suetsugu, Y Sato, T Ikeda, R Shirakawa, T Kita, ... Genes to cells 12 (11), 1255-1265, 2007 | 65 | 2007 |
Identification of protein kinase Cα as an essential, but not sufficient, cytosolic factor for Ca2+-induced α-and dense-core granule secretion in platelets A Yoshioka, R Shirakawa, H Nishioka, A Tabuchi, T Higashi, H Ozaki, ... Journal of Biological Chemistry 276 (42), 39379-39385, 2001 | 65 | 2001 |
Direct demonstration of involvement of protein kinase Cα in the Ca2+-induced platelet aggregation A Tabuchi, A Yoshioka, T Higashi, R Shirakawa, H Nishioka, T Kita, ... Journal of Biological Chemistry 278 (29), 26374-26379, 2003 | 61 | 2003 |
Constitutive GDP/GTP exchange and secretion-dependent GTP hydrolysis activity for Rab27 in platelets H Kondo, R Shirakawa, T Higashi, M Kawato, M Fukuda, T Kita, ... Journal of biological chemistry 281 (39), 28657-28665, 2006 | 60 | 2006 |
Flightless-I (Fli-I) regulates the actin assembly activity of diaphanous-related formins (DRFs) Daam1 and mDia1 in cooperation with active Rho GTPase T Higashi, T Ikeda, T Murakami, R Shirakawa, M Kawato, K Okawa, ... Journal of biological chemistry 285 (21), 16231-16238, 2010 | 59 | 2010 |
Regulation of platelet dense granule secretion by the Ral GTPase-exocyst pathway M Kawato, R Shirakawa, H Kondo, T Higashi, T Ikeda, K Okawa, S Fukai, ... Journal of biological chemistry 283 (1), 166-174, 2008 | 55 | 2008 |
A coronary artery disease-associated gene product, JCAD/KIAA1462, is a novel component of endothelial cell–cell junctions M Akashi, T Higashi, S Masuda, T Komori, M Furuse Biochemical and biophysical research communications 413 (2), 224-229, 2011 | 50 | 2011 |
MgcRacGAP restricts active RhoA at the cytokinetic furrow and both RhoA and Rac1 at cell–cell junctions in epithelial cells EB Breznau, AC Semack, T Higashi, AL Miller Molecular biology of the cell 26 (13), 2439-2455, 2015 | 48 | 2015 |