Martin D Brand
Martin D Brand
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Zitiert von
Zitiert von
Assessing mitochondrial dysfunction in cells
MD Brand, DG Nicholls
Biochemical Journal 435 (2), 297-312, 2011
Topology of superoxide production from different sites in the mitochondrial electron transport chain
J St-Pierre, JA Buckingham, SJ Roebuck, MD Brand
Journal of Biological Chemistry 277 (47), 44784-44790, 2002
Superoxide activates mitochondrial uncoupling proteins
KS Echtay, D Roussel, J St-Pierre, MB Jekabsons, S Cadenas, JA Stuart, ...
Nature 415 (6867), 96-99, 2002
Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins
MD Brand, C Affourtit, TC Esteves, K Green, AJ Lambert, S Miwa, ...
Free Radical Biology and Medicine 37 (6), 755-767, 2004
The sites and topology of mitochondrial superoxide production
MD Brand
Experimental gerontology 45 (7-8), 466-472, 2010
Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism: a novel regulatory mechanism altered in obesity
D Bach, S Pich, FX Soriano, N Vega, B Baumgartner, J Oriola, ...
Journal of Biological Chemistry 278 (19), 17190-17197, 2003
Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3
MD Brand, TC Esteves
Cell metabolism 2 (2), 85-93, 2005
Uncoupling to survive? The role of mitochondrial inefficiency in ageing
MD Brand
Experimental gerontology 35 (6-7), 811-820, 2000
A hierarchy of ATP-consuming processes in mammalian cells
F Buttgereit, MD Brand
Biochemical Journal 312 (1), 163-167, 1995
Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean
JC Clapham, JRS Arch, H Chapman, A Haynes, C Lister, GBT Moore, ...
Nature 406 (6794), 415-418, 2000
Mitochondrial proton and electron leaks
M Jastroch, AS Divakaruni, S Mookerjee, JR Treberg, MD Brand
Essays in biochemistry 47, 53-67, 2010
A signalling role for 4‐hydroxy‐2‐nonenal in regulation of mitochondrial uncoupling
KS Echtay, TC Esteves, JL Pakay, MB Jekabsons, AJ Lambert, ...
The EMBO journal 22 (16), 4103-4110, 2003
Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes
K Green, MD Brand, MP Murphy
Diabetes 53 (suppl 1), S110-S118, 2004
The causes and functions of mitochondrial proton leak
MD Brand, LF Chien, EK Ainscow, DFS Rolfe, RK Porter
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1187 (2), 132-139, 1994
Mitochondrial complex II can generate reactive oxygen species at high rates in both the forward and reverse reactions
CL Quinlan, AL Orr, IV Perevoshchikova, JR Treberg, BA Ackrell, ...
Journal of Biological Chemistry 287 (32), 27255-27264, 2012
Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling
MD Brand
Free Radical Biology and Medicine 100, 14-31, 2016
Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer
JR Speakman, DA Talbot, C Selman, S Snart, JS McLaren, P Redman, ...
Aging cell 3 (3), 87-95, 2004
Inhibitors of the quinone-binding site allow rapid superoxide production from mitochondrial NADH: ubiquinone oxidoreductase (complex I)
AJ Lambert, MD Brand
Journal of Biological Chemistry 279 (38), 39414-39420, 2004
Superoxide production by NADH: ubiquinone oxidoreductase (complex I) depends on the pH gradient across the mitochondrial inner membrane
AJ Lambert, MD Brand
Biochemical Journal 382 (2), 511-517, 2004
Superoxide activates mitochondrial uncoupling protein 2 from the matrix side: studies using targeted antioxidants
KS Echtay, MP Murphy, RAJ Smith, DA Talbot, MD Brand
Journal of Biological Chemistry 277 (49), 47129-47135, 2002
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