Nicole Koropatkin
Nicole Koropatkin
Assistant Professor of Microbiology and Immunology, University of MI Medical School
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A dietary fiber-deprived gut microbiota degrades the colonic mucus barrier and enhances pathogen susceptibility
MS Desai, AM Seekatz, NM Koropatkin, N Kamada, CA Hickey, M Wolter, ...
Cell 167 (5), 1339-1353. e21, 2016
How glycan metabolism shapes the human gut microbiota
NM Koropatkin, EA Cameron, EC Martens
Nature Reviews Microbiology 10 (5), 323-335, 2012
Complex glycan catabolism by the human gut microbiota: the Bacteroidetes Sus-like paradigm
EC Martens, NM Koropatkin, TJ Smith, JI Gordon
Journal of Biological Chemistry 284 (37), 24673-24677, 2009
A discrete genetic locus confers xyloglucan metabolism in select human gut Bacteroidetes
J Larsbrink, TE Rogers, GR Hemsworth, LS McKee, AS Tauzin, O Spadiut, ...
Nature 506 (7489), 498-502, 2014
Starch catabolism by a prominent human gut symbiont is directed by the recognition of amylose helices
NM Koropatkin, EC Martens, JI Gordon, TJ Smith
Structure 16 (7), 1105-1115, 2008
Polysaccharide degradation by the intestinal microbiota and its influence on human health and disease
DW Cockburn, NM Koropatkin
Journal of molecular biology 428 (16), 3230-3252, 2016
SusG: a unique cell-membrane-associated α-amylase from a prominent human gut symbiont targets complex starch molecules
NM Koropatkin, TJ Smith
Structure 18 (2), 200-215, 2010
The Sus operon: a model system for starch uptake by the human gut Bacteroidetes
MH Foley, DW Cockburn, NM Koropatkin
Cellular and Molecular Life Sciences 73 (14), 2603-2617, 2016
Dynamic responses of Bacteroides thetaiotaomicron during growth on glycan mixtures
TE Rogers, NA Pudlo, NM Koropatkin, JSK Bell, M Moya Balasch, ...
Molecular microbiology 88 (5), 876-890, 2013
Unique Organization of Extracellular Amylases into Amylosomes in the Resistant Starch-Utilizing Human Colonic Firmicutes Bacterium Ruminococcus bromii
X Ze, Y Ben David, JA Laverde-Gomez, B Dassa, PO Sheridan, ...
MBio 6 (5), e01058-15, 2015
Multidomain carbohydrate-binding proteins involved in Bacteroides thetaiotaomicron starch metabolism
EA Cameron, MA Maynard, CJ Smith, TJ Smith, NM Koropatkin, ...
Journal of Biological Chemistry 287 (41), 34614-34625, 2012
Molecular details of a starch utilization pathway in the human gut symbiont Eubacterium rectale
DW Cockburn, NI Orlovsky, MH Foley, KJ Kwiatkowski, CM Bahr, ...
Molecular microbiology 95 (2), 209-230, 2015
Atomic structure of a nitrate-binding protein crucial for photosynthetic productivity
NM Koropatkin, HB Pakrasi, TJ Smith
Proceedings of the National Academy of Sciences 103 (26), 9820-9825, 2006
The structure of a cyanobacterial bicarbonate transport protein, CmpA
NM Koropatkin, DW Koppenaal, HB Pakrasi, TJ Smith
Journal of Biological Chemistry 282 (4), 2606-2614, 2007
Ruminococcal cellulosome systems from rumen to human
Y Ben David, B Dassa, I Borovok, R Lamed, NM Koropatkin, EC Martens, ...
Environmental microbiology 17 (9), 3407-3426, 2015
Galactomannan catabolism conferred by a polysaccharide utilization locus of Bacteroides ovatus: enzyme synergy and crystal structure of a β-mannanase
V Bågenholm, SK Reddy, H Bouraoui, J Morrill, E Kulcinskaja, CM Bahr, ...
Journal of Biological Chemistry 292 (1), 229-243, 2017
Multifunctional nutrient-binding proteins adapt human symbiotic bacteria for glycan competition in the gut by separately promoting enhanced sensing and catalysis
EA Cameron, KJ Kwiatkowski, BH Lee, BR Hamaker, NM Koropatkin, ...
MBio 5 (5), e01441-14, 2014
Glycan recognition by the Bacteroidetes Sus-like systems
DN Bolam, NM Koropatkin
Current opinion in structural biology 22 (5), 563-569, 2012
A polysaccharide utilization locus from Flavobacterium johnsoniae enables conversion of recalcitrant chitin
J Larsbrink, Y Zhu, SS Kharade, KJ Kwiatkowski, VGH Eijsink, ...
Biotechnology for biofuels 9 (1), 1-16, 2016
Enzymatic profiling of cellulosomal enzymes from the human gut bacterium, Ruminococcus champanellensis, reveals a fine‐tuned system for cohesin‐dockerin …
S Moraïs, YB David, L Bensoussan, SH Duncan, NM Koropatkin, ...
Environmental microbiology 18 (2), 542-556, 2016
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