Antibody production, design and use for biosensor-based applications PJ Conroy, S Hearty, P Leonard, RJ O’Kennedy Seminars in cell & developmental biology 20 (1), 10-26, 2009 | 378 | 2009 |
Aberrant PSA glycosylation—a sweet predictor of prostate cancer S Gilgunn, PJ Conroy, R Saldova, PM Rudd, RJ O'kennedy Nature Reviews Urology 10 (2), 99-107, 2013 | 252 | 2013 |
A tale of two specificities: bispecific antibodies for therapeutic and diagnostic applications H Byrne, PJ Conroy, JC Whisstock, RJ O’Kennedy Trends in biotechnology 31 (11), 621-632, 2013 | 203 | 2013 |
Structure of the poly-C9 component of the complement membrane attack complex NV Dudkina, BA Spicer, CF Reboul, PJ Conroy, N Lukoyanova, ... Nature communications 7 (1), 10588, 2016 | 125 | 2016 |
The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1 SS Pang, C Bayly-Jones, M Radjainia, BA Spicer, RHP Law, AW Hodel, ... Nature communications 10 (1), 4288, 2019 | 63 | 2019 |
Homodimerization attenuates the anti-inflammatory activity of interleukin-37 AM Ellisdon, CA Nold-Petry, L D’Andrea, SX Cho, JC Lao, I Rudloff, ... Science immunology 2 (8), eaaj1548, 2017 | 61 | 2017 |
Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA CJ Holland, RM Crean, JM Pentier, B de Wet, A Lloyd, V Srikannathasan, ... The Journal of clinical investigation 130 (5), 2673-2688, 2020 | 56 | 2020 |
The first transmembrane region of complement component-9 acts as a brake on its self-assembly BA Spicer, RHP Law, TT Caradoc-Davies, SM Ekkel, C Bayly-Jones, ... Nature Communications 9 (1), 3266, 2018 | 51 | 2018 |
Surface plasmon resonance for vaccine design and efficacy studies: recent applications and future trends S Hearty, PJ Conroy, BV Ayyar, B Byrne, R O’Kennedy Expert review of vaccines 9 (6), 645-664, 2010 | 51 | 2010 |
Tranexamic acid is an active site inhibitor of urokinase plasminogen activator G Wu, BA Mazzitelli, AJ Quek, MJ Veldman, PJ Conroy, ... Blood advances 3 (5), 729-733, 2019 | 38 | 2019 |
X-ray crystal structure of plasmin with tranexamic acid–derived active site inhibitors RHP Law, G Wu, EWW Leung, K Hidaka, AJ Quek, TT Caradoc-Davies, ... Blood advances 1 (12), 766-771, 2017 | 37 | 2017 |
Electrochemiluminescence platform for the detection of C-reactive proteins: application of recombinant antibody technology to cardiac biomarker detection EJ O'Reilly, PJ Conroy, S Hearty, TE Keyes, R O'Kennedy, RJ Forster, ... RSC advances 5 (83), 67874-67877, 2015 | 36 | 2015 |
Perforin—A key (shaped) weapon in the immunological arsenal BA Spicer, PJ Conroy, RHP Law, I Voskoboinik, JC Whisstock Seminars in cell & developmental biology 72, 117-123, 2017 | 35 | 2017 |
Structural basis for Ca2+-mediated interaction of the perforin C2 domain with lipid membranes H Yagi, PJ Conroy, EWW Leung, RHP Law, JA Trapani, I Voskoboinik, ... Journal of Biological Chemistry 290 (42), 25213-25226, 2015 | 34 | 2015 |
Reconciling the structural attributes of avian antibodies PJ Conroy, RHP Law, S Gilgunn, S Hearty, TT Caradoc-Davies, G Lloyd, ... Journal of Biological Chemistry 289 (22), 15384-15392, 2014 | 34 | 2014 |
Cardiac troponin I: a case study in rational antibody design for human diagnostics PJ Conroy, RJ O'Kennedy, S Hearty Protein Engineering, Design & Selection 25 (6), 295-305, 2012 | 30 | 2012 |
Antibodies: From novel repertoires to defining and refining the structure of biologically important targets PJ Conroy, RHP Law, TT Caradoc-Davies, JC Whisstock Methods 116, 12-22, 2017 | 25 | 2017 |
Comprehensive N-glycan profiling of avian immunoglobulin Y S Gilgunn, S Millán Martín, MR Wormald, J Zapatero-Rodríguez, ... PloS one 11 (7), e0159859, 2016 | 24 | 2016 |
Circumventing the stability-function trade-off in an engineered FN3 domain BT Porebski, PJ Conroy, N Drinkwater, P Schofield, R Vazquez-Lombardi, ... Protein Engineering, Design and Selection 29 (11), 541-550, 2016 | 21 | 2016 |
Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3 DAK Traore, JA Wisniewski, SF Flanigan, PJ Conroy, S Panjikar, YF Mok, ... Nature communications 9 (1), 3732, 2018 | 20 | 2018 |