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Molly Ohainle
Molly Ohainle
Verified email at fredhutch.org - Homepage
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Dynamics of dengue disease severity determined by the interplay between viral genetics and serotype-specific immunity
M OhAinle, A Balmaseda, AR Macalalad, Y Tellez, MC Zody, S Saborío, ...
Science translational medicine 3 (114), 114ra128-114ra128, 2011
3132011
Antiretroelement activity of APOBEC3H was lost twice in recent human evolution
M OhAinle, JA Kerns, MMH Li, HS Malik, M Emerman
Cell host & microbe 4 (3), 249-259, 2008
2282008
Adaptive Evolution and Antiviral Activity of the Conserved Mammalian Cytidine Deaminase APOBEC3H
M OhAinle, JA Kerns, HS Malik, M Emerman
Journal of virology 80 (8), 3853-3862, 2006
2222006
A virus-packageable CRISPR screen identifies host factors mediating interferon inhibition of HIV
M OhAinle, L Helms, J Vermeire, F Roesch, D Humes, R Basom, ...
Elife 7, e39823, 2018
1232018
TRIM34 restricts HIV-1 and SIV capsids in a TRIM5α-dependent manner
M Ohainle, K Kim, S Komurlu Keceli, A Felton, E Campbell, J Luban, ...
PLoS pathogens 16 (4), e1008507, 2020
462020
Identification of DAXX as a restriction factor of SARS-CoV-2 through a CRISPR/Cas9 screen
A Mac Kain, G Maarifi, SM Aicher, N Arhel, A Baidaliuk, S Munier, ...
Nature Communications 13 (1), 2442, 2022
302022
A CRISPR screen for factors regulating SAMHD1 degradation identifies IFITMs as potent inhibitors of lentiviral particle delivery
F Roesch, M OhAinle, M Emerman
Retrovirology 15, 1-16, 2018
262018
Macaque interferon-induced transmembrane proteins limit replication of SHIV strains in an Envelope-dependent manner
A Sharma, RN McLaughlin Jr, RS Basom, C Kikawa, M OhAinle, JS Yount, ...
PLoS pathogens 15 (7), e1007925, 2019
132019
A modular CRISPR screen identifies individual and combination pathways contributing to HIV-1 latency
E Hsieh, DH Janssens, PJ Paddison, EP Browne, S Henikoff, M OhAinle, ...
PLoS Pathogens 19 (1), e1011101, 2023
122023
12 dengue pathogenesis: viral factors.
M OhAinle, E Harris
Dengue Dengue Hemorrhagic Fever 2014 (229), 2014
102014
HIV-CRISPR: a CRISPR/Cas9 screening method to identify genes affecting HIV replication
F Roesch, M OhAinle
Bio-protocol 10 (9), e3614-e3614, 2020
72020
Primate TRIM34 is a broadly-acting, TRIM5-dependent lentiviral restriction factor
J Twentyman, A Khalifeh, AL Felton, M Emerman, M Ohainle
Retrovirology 20 (1), 15, 2023
52023
A virus-Packageable CRISPR system identifies host dependency factors Co-opted by multiple HIV-1 strains
VR Montoya, TM Ready, A Felton, SR Fine, M OhAinle, M Emerman
Mbio 14 (1), e00009-23, 2023
22023
A balancing act between primate lentiviruses and their receptor
M Ohainle, HS Malik
Proceedings of the National Academy of Sciences 118 (20), e2104741118, 2021
22021
TRIM34 acts with TRIM5 to restrict HIV and SIV capsids
M Ohainle, K Kim, S Keceli, A Felton, E Campbell, J Luban, M Emerman
BioRxiv, 820886, 2019
22019
Patterns of evolution of TRIM genes highlight the evolutionary plasticity of antiviral effectors in mammals
AP Fernandes, M OhAinle, PJ Esteves
Genome Biology and Evolution 15 (12), evad209, 2023
12023
Capsid-dependent lentiviral restrictions
J Twentyman, M Emerman, M Ohainle
Journal of Virology 98 (4), e00308-24, 2024
2024
A Virus-Packageable CRISPR System Identifies Host Dependency Factors Across Multiple HIV-1 Strains
VR Montoya, TM Ready, A Felton, SR Fine, M OhAinle, M Emerman
bioRxiv, 2022.11. 03.515041, 2022
2022
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M Ohainle, K Kim, S Keceli, A Felton, E Campbell, J Luban, M Emerman
2019
TRIM34 acts with TRIM5 to restrict HIV and SIV capsids [preprint]
M Ohainle, K Kim, S Keceli, A Felton, E Campbell, J Luban, M Emerman
2019
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