An equation to estimate the difference between theoretically predicted and SDS PAGE-displayed molecular weights for an acidic peptide Y Guan, Q Zhu, D Huang, S Zhao, L Jan Lo, J Peng Scientific reports 5 (1), 13370, 2015 | 154 | 2015 |
Def defines a conserved nucleolar pathway that leads p53 to proteasome-independent degradation T Tao, H Shi, Y Guan, D Huang, Y Chen, DP Lane, J Chen, J Peng Cell research 23 (5), 620-634, 2013 | 115 | 2013 |
Consequences of mutant TET2 on clonality and subclonal hierarchy CM Hirsch, A Nazha, K Kneen, ME Abazeed, M Meggendorfer, ... Leukemia 32 (8), 1751-1761, 2018 | 64 | 2018 |
Germline loss-of-function SAMD9 and SAMD9L alterations in adult myelodysplastic syndromes Y Nagata, S Narumi, Y Guan, BP Przychodzen, CM Hirsch, H Makishima, ... Blood, The Journal of the American Society of Hematology 132 (21), 2309-2313, 2018 | 54 | 2018 |
A Therapeutic Strategy for Preferential Targeting of TET2-Mutant and TET Dioxygenase–Deficient Cells in Myeloid Neoplasms Y Guan, AD Tiwari, JG Phillips, M Hasipek, DR Grabowski, S Pagliuca, ... Blood cancer discovery 2 (2), 146-161, 2021 | 47 | 2021 |
Invariant phenotype and molecular association of biallelic TET2 mutant myeloid neoplasia H Awada, Y Nagata, A Goyal, MF Asad, B Patel, CM Hirsch, ... Blood advances 3 (3), 339-349, 2019 | 40 | 2019 |
Phosphorylation of Def regulates nucleolar p53 turnover and cell cycle progression through Def recruitment of Calpain3 Y Guan, D Huang, F Chen, C Gao, T Tao, H Shi, S Zhao, Z Liao, LJ Lo, ... PLoS Biology 14 (9), e1002555, 2016 | 34 | 2016 |
Context dependent effects of ascorbic acid treatment in TET2 mutant myeloid neoplasia Y Guan, EF Greenberg, M Hasipek, S Chen, X Liu, CM Kerr, D Gackowski, ... Communications biology 3 (1), 493, 2020 | 33 | 2020 |
The similarity of class II HLA genotypes defines patterns of autoreactivity in idiopathic bone marrow failure disorders S Pagliuca, C Gurnari, H Awada, A Kishtagari, S Kongkiatkamon, ... Blood, The Journal of the American Society of Hematology 138 (26), 2781-2798, 2021 | 31 | 2021 |
Eltrombopag inhibits TET dioxygenase to contribute to hematopoietic stem cell expansion in aplastic anemia Y Guan, M Hasipek, D Jiang, AD Tiwari, DR Grabowski, S Pagliuca, ... The Journal of clinical investigation 132 (4), 2022 | 20 | 2022 |
TET2 mutations as a part of DNA dioxygenase deficiency in myelodysplastic syndromes C Gurnari, S Pagliuca, Y Guan, V Adema, CE Hershberger, Y Ni, ... Blood advances 6 (1), 100-107, 2022 | 12 | 2022 |
Clinical and basic implications of dynamic T cell receptor clonotyping in hematopoietic cell transplantation S Pagliuca, C Gurnari, S Hong, R Zhao, S Kongkiatkamon, L Terkawi, ... JCI insight 6 (13), 2021 | 12 | 2021 |
Therapeutic targeting of protein disulfide isomerase PDIA1 in multiple myeloma M Hasipek, D Grabowski, Y Guan, RR Alugubelli, AD Tiwari, X Gu, ... Cancers 13 (11), 2649, 2021 | 11 | 2021 |
TET-dioxygenase deficiency in oncogenesis and its targeting for tumor-selective therapeutics Y Guan, M Hasipek, AD Tiwari, JP Maciejewski, BK Jha Seminars in hematology 58 (1), 27-34, 2021 | 11 | 2021 |
Genomic biomarkers predict response/resistance to lenalidomide in non-Del (5q) myelodysplastic syndromes YF Madanat, MA Sekeres, S Mukherjee, CM Hirsch, Y Guan, Y Nagata, ... Blood 132, 1797, 2018 | 8 | 2018 |
A machine learning model of response to hypomethylating agents in myelodysplastic syndromes N Radakovich, DA Sallman, R Buckstein, A Brunner, A Dezern, ... IScience 25 (10), 2022 | 5 | 2022 |
SAR insights into TET2 catalytic domain inhibition: synthesis of 2-hydroxy-4-methylene-pentanedicarboxylates AD Tiwari, Y Guan, DR Grabowski, JP Maciejewski, BK Jha, JG Phillips Bioorganic & medicinal chemistry 39, 116141, 2021 | 5 | 2021 |
A therapeutic strategy for preferential targeting of TET2 mutant and TET-dioxygenase deficient cells in myeloid neoplasms. Blood cancer discovery. 2021; 2: 146–61 Y Guan, AD Tiwari, JG Phillips, M Hasipek, DR Grabowski, S Pagliuca, ... Proc Natl Acad Sci US A 118, 2021 | 5 | 2021 |
Mutational patterns and clonal architecture of therapy-related acute myeloid Leukemia H Awada, T Kuzmanovic, A Kishtagari, J Durrani, A Durmaz, S Hong, ... Blood 134, 1405, 2019 | 5 | 2019 |
A zebrafish cell culture assay for the identification of microRNA targets W Liu, Y Guan, P Collodi Zebrafish 7 (4), 343-348, 2010 | 5 | 2010 |