The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J M Levitus, Q Waisfisz, BC Godthelp, Y Vries, S Hussain, WW Wiegant, ... Nature genetics 37 (9), 934-935, 2005 | 541 | 2005 |
The yeast Fun30 and human SMARCAD1 chromatin remodellers promote DNA end resection T Costelloe, R Louge, N Tomimatsu, B Mukherjee, E Martini, B Khadaroo, ... Nature 489 (7417), 581-584, 2012 | 296 | 2012 |
A DNA-PKcs mutation in a radiosensitive T–B– SCID patient inhibits Artemis activation and nonhomologous end-joining M Van Der Burg, H IJspeert, NS Verkaik, T Turul, WW Wiegant, ... The Journal of clinical investigation 119 (1), 91-98, 2009 | 292 | 2009 |
The NuRD chromatin–remodeling complex regulates signaling and repair of DNA damage G Smeenk, WW Wiegant, H Vrolijk, AP Solari, A Pastink, H van Attikum Journal of Cell Biology 190 (5), 741-749, 2010 | 264 | 2010 |
Selective loss of PARG restores PARylation and counteracts PARP inhibitor-mediated synthetic lethality E Gogola, AA Duarte, JR de Ruiter, WW Wiegant, JA Schmid, R de Bruijn, ... Cancer cell 33 (6), 1078-1093. e12, 2018 | 258 | 2018 |
A new type of radiosensitive T–B–NK+ severe combined immunodeficiency caused by a LIG4 mutation M van der Burg, LR van Veelen, NS Verkaik, WW Wiegant, NG Hartwig, ... The Journal of clinical investigation 116 (1), 137-145, 2006 | 210 | 2006 |
Mammalian Rad51C contributes to DNA cross-link resistance, sister chromatid cohesion and genomic stability BC Godthelp, WW Wiegant, A van Duijn-Goedhart, OD Schärer, ... Nucleic acids research 30 (10), 2172-2182, 2002 | 174 | 2002 |
Poly (ADP-ribosyl) ation links the chromatin remodeler SMARCA5/SNF2H to RNF168-dependent DNA damage signaling G Smeenk, WW Wiegant, JA Marteijn, MS Luijsterburg, N Sroczynski, ... Journal of cell science 126 (4), 889-903, 2013 | 155 | 2013 |
Radiosensitive SCID patients with Artemis gene mutations show a complete B-cell differentiation arrest at the pre–B-cell receptor checkpoint in bone marrow JG Noordzij, NS Verkaik, M van der Burg, LR van Veelen, ... Blood, The Journal of the American Society of Hematology 101 (4), 1446-1452, 2003 | 121 | 2003 |
A new non‐catalytic role for ubiquitin ligase RNF8 in unfolding higher‐order chromatin structure MS Luijsterburg, K Acs, L Ackermann, WW Wiegant, S Bekker‐Jensen, ... The EMBO journal 31 (11), 2511-2527, 2012 | 118 | 2012 |
Suppression of the DNA repair defects of BRCA2-deficient cells with heterologous protein fusions H Saeki, N Siaud, N Christ, WW Wiegant, PPW Van Buul, M Han, ... Proceedings of the National Academy of Sciences 103 (23), 8768-8773, 2006 | 118 | 2006 |
ZMYND8 co-localizes with NuRD on target genes and regulates poly (ADP-ribose)-dependent recruitment of GATAD2A/NuRD to sites of DNA damage CG Spruijt, MS Luijsterburg, R Menafra, RGH Lindeboom, PWTC Jansen, ... Cell reports 17 (3), 783-798, 2016 | 111 | 2016 |
Inducibility of nuclear Rad51 foci after DNA damage distinguishes all Fanconi anemia complementation groups from D1/BRCA2 BC Godthelp, WW Wiegant, Q Waisfisz, AL Medhurst, F Arwert, H Joenje, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 594 (1 …, 2006 | 93 | 2006 |
The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80 D Typas, MS Luijsterburg, WW Wiegant, M Diakatou, A Helfricht, ... Nucleic acids research 43 (14), 6919-6933, 2015 | 88 | 2015 |
A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation MS Luijsterburg, D Typas, MC Caron, WW Wiegant, D Heuvel, ... Elife 6, e20922, 2017 | 86 | 2017 |
WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks P Caron, T Pankotai, WW Wiegant, MAX Tollenaere, A Furst, ... Genes & development 33 (11-12), 684-704, 2019 | 83 | 2019 |
Ataxin‐3 consolidates the MDC 1‐dependent DNA double‐strand break response by counteracting the SUMO‐targeted ubiquitin ligase RNF 4 A Pfeiffer, MS Luijsterburg, K Acs, WW Wiegant, A Helfricht, LK Herzog, ... The EMBO journal 36 (8), 1066-1083, 2017 | 83 | 2017 |
Role of Artemis in DSB repair and guarding chromosomal stability following exposure to ionizing radiation at different stages of cell cycle F Darroudi, W Wiegant, M Meijers, AA Friedl, M van der Burg, J Fomina, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 615 (1 …, 2007 | 69 | 2007 |
Functional analysis of genetic variants in the high-risk breast cancer susceptibility gene PALB2 RACM Boonen, A Rodrigue, C Stoepker, WW Wiegant, B Vroling, ... Nature communications 10 (1), 5296, 2019 | 63 | 2019 |
Remodeling and spacing factor 1 (RSF1) deposits centromere proteins at DNA double-strand breaks to promote non-homologous end-joining H Helfricht,A., Wiegant,W.W., Thijssen,P.E Cell Cycle 12 (16), 2013 | 62 | 2013 |