Wouter W Wiegant
Wouter W Wiegant
Research Technician at The Haico van Attikum Research group, LUMC, the Netherlands
Bestätigte E-Mail-Adresse bei lumc.nl
TitelZitiert vonJahr
The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J
M Levitus, Q Waisfisz, BC Godthelp, Y De Vries, S Hussain, WW Wiegant, ...
Nature genetics 37 (9), 934-935, 2005
A DNA-PKcs mutation in a radiosensitive TB SCID patient inhibits Artemis activation and nonhomologous end-joining
M Van Der Burg, H IJspeert, NS Verkaik, T Turul, WW Wiegant, ...
The Journal of clinical investigation 119 (1), 91-98, 2009
The NuRD chromatin–remodeling complex regulates signaling and repair of DNA damage
G Smeenk, WW Wiegant, H Vrolijk, AP Solari, A Pastink, H van Attikum
Journal of Cell Biology 190 (5), 741-749, 2010
The yeast Fun30 and human SMARCAD1 chromatin remodellers promote DNA end resection
T Costelloe, R Louge, N Tomimatsu, B Mukherjee, E Martini, B Khadaroo, ...
Nature 489 (7417), 581-584, 2012
A new type of radiosensitive TBNK+ severe combined immunodeficiency caused by a LIG4 mutation
M van der Burg, LR van Veelen, NS Verkaik, WW Wiegant, NG Hartwig, ...
The Journal of clinical investigation 116 (1), 137-145, 2006
Mammalian Rad51C contributes to DNA cross-link resistance, sister chromatid cohesion and genomic stability
BC Godthelp, WW Wiegant, A van Duijn-Goedhart, OD Schärer, ...
Nucleic acids research 30 (10), 2172-2182, 2002
Radiosensitive SCID patients with Artemis gene mutations show a complete B-cell differentiation arrest at the pre–B-cell receptor checkpoint in bone marrow
JG Noordzij, NS Verkaik, M van der Burg, LR van Veelen, ...
Blood 101 (4), 1446-1452, 2003
PARP1 links CHD2-mediated chromatin expansion and H3. 3 deposition to DNA repair by non-homologous end-joining
MS Luijsterburg, I de Krijger, WW Wiegant, RG Shah, G Smeenk, ...
Molecular cell 61 (4), 547-562, 2016
Poly (ADP-ribosyl) ation links the chromatin remodeler SMARCA5/SNF2H to RNF168-dependent DNA damage signaling
G Smeenk, WW Wiegant, JA Marteijn, MS Luijsterburg, N Sroczynski, ...
Journal of cell science 126 (4), 889-903, 2013
Suppression of the DNA repair defects of BRCA2-deficient cells with heterologous protein fusions
H Saeki, N Siaud, N Christ, WW Wiegant, PPW Van Buul, M Han, ...
Proceedings of the National Academy of Sciences 103 (23), 8768-8773, 2006
A new non‐catalytic role for ubiquitin ligase RNF8 in unfolding higher‐order chromatin structure
MS Luijsterburg, K Acs, L Ackermann, WW Wiegant, S Bekker‐Jensen, ...
The EMBO journal 31 (11), 2511-2527, 2012
Inducibility of nuclear Rad51 foci after DNA damage distinguishes all Fanconi anemia complementation groups from D1/BRCA2
BC Godthelp, WW Wiegant, Q Waisfisz, AL Medhurst, F Arwert, H Joenje, ...
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 594 (1 …, 2006
Role of Artemis in DSB repair and guarding chromosomal stability following exposure to ionizing radiation at different stages of cell cycle
F Darroudi, W Wiegant, M Meijers, AA Friedl, M van der Burg, J Fomina, ...
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 615 (1 …, 2007
Selective loss of PARG restores PARylation and counteracts PARP inhibitor-mediated synthetic lethality
E Gogola, AA Duarte, JR de Ruiter, WW Wiegant, JA Schmid, R de Bruijn, ...
Cancer cell 33 (6), 1078-1093. e12, 2018
Chinese hamster cell mutant, V-C8, a model for analysis of Brca2 function
WW Wiegant, RM Overmeer, BC Godthelp, PPW van Buul, MZ Zdzienicka
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 600 (1 …, 2006
ZMYND8 co-localizes with NuRD on target genes and regulates poly (ADP-ribose)-dependent recruitment of GATAD2A/NuRD to sites of DNA damage
CG Spruijt, MS Luijsterburg, R Menafra, RGH Lindeboom, PWTC Jansen, ...
Cell reports 17 (3), 783-798, 2016
The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80
D Typas, MS Luijsterburg, WW Wiegant, M Diakatou, A Helfricht, ...
Nucleic acids research 43 (14), 6919-6933, 2015
Remodeling and spacing factor 1 (RSF1) deposits centromere proteins at DNA double-strand breaks to promote non-homologous end-joining
H Helfricht,A., Wiegant,W.W., Thijssen,P.E
Cell Cycle 12 (16), 2013
Ataxin‐3 consolidates the MDC1‐dependent DNA double‐strand break response by counteracting the SUMO‐targeted ubiquitin ligase RNF4
A Pfeiffer, MS Luijsterburg, K Acs, WW Wiegant, A Helfricht, LK Herzog, ...
The EMBO journal 36 (8), 1066-1083, 2017
A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation
MS Luijsterburg, D Typas, MC Caron, WW Wiegant, D van den Heuvel, ...
Elife 6, e20922, 2017
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