| Connecting copper and cancer: from transition metal signalling to metalloplasia EJ Ge, AI Bush, A Casini, PA Cobine, JR Cross, GM DeNicola, QP Dou, ... Nature Reviews Cancer 22 (2), 102-113, 2022 | 629 | 2022 |
| High copper selectively alters lipid metabolism and cell cycle machinery in the mouse model of Wilson disease D Huster, TD Purnat, JL Burkhead, M Ralle, O Fiehn, F Stuckert, NE Olson, ... Journal of Biological Chemistry 282 (11), 8343-8355, 2007 | 259 | 2007 |
| Peroxo-, oxo-, and hydroxo-bridged dicopper complexes: Observation of exogenous hydrocarbon substrate oxidation HV Obias, Y Lin, NN Murthy, E Pidcock, EI Solomon, M Ralle, ... Journal of the American Chemical Society 120 (49), 12960-12961, 1998 | 228 | 1998 |
| Redox‐sensitive transcriptional control by a thiol/disulphide switch in the global regulator, Spx S Nakano, KN Erwin, M Ralle, P Zuber Molecular microbiology 55 (2), 498-510, 2005 | 181 | 2005 |
| The N-terminal metal-binding site 2 of the Wilson's Disease Protein plays a key role in the transfer of copper from Atox1 JM Walker, D Huster, M Ralle, CT Morgan, NJ Blackburn, S Lutsenko Journal of Biological Chemistry 279 (15), 15376-15384, 2004 | 135 | 2004 |
| Probing the role of axial methionine in the blue copper center of azurin with unnatural amino acids SM Berry, M Ralle, DW Low, NJ Blackburn, Y Lu Journal of the American Chemical Society 125 (29), 8760-8768, 2003 | 128 | 2003 |
| X-ray absorption spectroscopy of the copper chaperone HAH1 reveals a linear two-coordinate Cu (I) center capable of adduct formation with exogenous thiols and phosphines M Ralle, S Lutsenko, NJ Blackburn Journal of Biological Chemistry 278 (25), 23163-23170, 2003 | 128 | 2003 |
| Major changes in copper coordination accompany reduction of peptidylglycine monooxygenase: implications for electron transfer and the catalytic mechanism NJ Blackburn, FC Rhames, M Ralle, S Jaron Journal of Biological Inorganic Chemistry 5, 341-353, 2000 | 125 | 2000 |
| Ctr2 regulates biogenesis of a cleaved form of mammalian Ctr1 metal transporter lacking the copper-and cisplatin-binding ecto-domain H Öhrvik, Y Nose, LK Wood, BE Kim, SC Gleber, M Ralle, DJ Thiele Proceedings of the National Academy of Sciences 110 (46), E4279-E4288, 2013 | 123 | 2013 |
| Wilson disease at a single cell level: intracellular copper trafficking activates compartment-specific responses in hepatocytes M Ralle, D Huster, S Vogt, W Schirrmeister, JL Burkhead, TR Capps, ... Journal of biological chemistry 285 (40), 30875-30883, 2010 | 110 | 2010 |
| Obesity is associated with copper elevation in serum and tissues H Yang, CN Liu, RM Wolf, M Ralle, S Dev, H Pierson, F Askin, KE Steele, ... Metallomics 11 (8), 1363-1371, 2019 | 93 | 2019 |
| Altered copper homeostasis underlies sensitivity of hepatocellular carcinoma to copper chelation CI Davis, X Gu, RM Kiefer, M Ralle, TP Gade, DC Brady Metallomics 12 (12), 1995-2008, 2020 | 90 | 2020 |
| Phytic acid as a potential treatment for Alzheimer's pathology: evidence from animal and in vitro models TS Anekonda, TL Wadsworth, R Sabin, K Frahler, C Harris, B Petriko, ... Journal of Alzheimer's Disease 23 (1), 21-35, 2011 | 88 | 2011 |
| Spectroscopic Characterization of an Engineered Purple CuA Center in Azurin MT Hay, MC Ang, DR Gamelin, EI Solomon, WE Antholine, M Ralle, ... Inorganic Chemistry 37 (2), 191-198, 1998 | 81 | 1998 |
| The function of ATPase copper transporter ATP7B in intestine H Pierson, A Muchenditsi, BE Kim, M Ralle, N Zachos, D Huster, ... Gastroenterology 154 (1), 168-180. e5, 2018 | 80 | 2018 |
| Domains I and III of the human copper chaperone for superoxide dismutase interact via a cysteine-bridged dicopper (I) cluster JF Eisses, JP Stasser, M Ralle, JH Kaplan, NJ Blackburn Biochemistry 39 (25), 7337-7342, 2000 | 79 | 2000 |
| The Menkes Disease Protein Binds Copper via Novel 2-Coordinate Cu (I)− Cysteinates in the N-Terminal Domain M Ralle, MJ Cooper, S Lutsenko, NJ Blackburn Journal of the American Chemical Society 120 (51), 13525-13526, 1998 | 77 | 1998 |
| Spectroscopic analysis of the trinuclear cluster in the Fet3 protein from yeast, a multinuclear copper oxidase NJ Blackburn, M Ralle, R Hassett, DJ Kosman Biochemistry 39 (9), 2316-2324, 2000 | 76 | 2000 |
| The contact activation inhibitor AB023 in heparin-free hemodialysis: results of a randomized phase 2 clinical trial CU Lorentz, EI Tucker, NG Verbout, JJ Shatzel, SR Olson, BD Markway, ... Blood, The Journal of the American Society of Hematology 138 (22), 2173-2184, 2021 | 71 | 2021 |
| Quantitative imaging of metals in tissues M Ralle, S Lutsenko Biometals 22, 197-205, 2009 | 71 | 2009 |
Svetlana LutsenkoJohns Hopkins UniversityBestätigte E-Mail-Adresse bei jhmi.edu
