| Homocysteine, folate, methylation, and monoamine metabolism in depression T Bottiglieri, M Laundy, R Crellin, BK Toone, MWP Carney, EH Reynolds Journal of neurology, neurosurgery & psychiatry 69 (2), 228-232, 2000 | 819 | 2000 |
| Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition Z Chen, AC Karaplis, SL Ackerman, IP Pogribny, S Melnyk, ... Human molecular genetics 10 (5), 433-444, 2001 | 772 | 2001 |
| High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial PS Aisen, LS Schneider, M Sano, R Diaz-Arrastia, CH Van Dyck, ... Jama 300 (15), 1774-1783, 2008 | 640 | 2008 |
| GABA, gamma-hydroxybutyric acid, and neurological disease CGT Wong, T Bottiglieri, OC Snead Annals of neurology 54 (6; SUPP), S3-S12, 2003 | 617 | 2003 |
| Folate, Vitamin B12, and Neuropsychiatric Disorders T Bottiglieri Nutrition reviews 54 (12), 382-390, 1996 | 526 | 1996 |
| Folate, vitamin B12, and homocysteine in major depressive disorder. M Fava, JS Borus, JE Alpert, AA Nierenberg, JF Rosenbaum, T Bottiglieri The American journal of psychiatry 154 (3), 426-428, 1997 | 481 | 1997 |
| Homocysteine and folate metabolism in depression T Bottiglieri Progress in Neuro-Psychopharmacology and Biological Psychiatry 29 (7), 1103-1112, 2005 | 422 | 2005 |
| S-Adenosyl-L-methionine (SAMe): from the bench to the bedside—molecular basis of a pleiotrophic molecule T Bottiglieri The American journal of clinical nutrition 76 (5), 1151S-1157S, 2002 | 404 | 2002 |
| Plasma β-amyloid and white matter lesions in AD, MCI, and cerebral amyloid angiopathy ME Gurol, MC Irizarry, EE Smith, S Raju, R Diaz-Arrastia, T Bottiglieri, ... Neurology 66 (1), 23-29, 2006 | 403 | 2006 |
| Cerebrospinal fluid S-adenosylmethionine in depression and dementia: effects of treatment with parenteral and oral S-adenosylmethionine. T Bottiglieri, P Godfrey, T Flynn, MW Carney, BK Toone, EH Reynolds Journal of Neurology, Neurosurgery & Psychiatry 53 (12), 1096-1098, 1990 | 340 | 1990 |
| High-dose oral N-acetylcysteine, a glutathione prodrug, modulates inflammation in cystic fibrosis R Tirouvanziam, CK Conrad, T Bottiglieri, LA Herzenberg, RB Moss, ... Proceedings of the National Academy of Sciences 103 (12), 4628-4633, 2006 | 337 | 2006 |
| l-Methylfolate as Adjunctive Therapy for SSRI-Resistant Major Depression: Results of Two Randomized, Double-Blind, Parallel-Sequential Trials GI Papakostas, RC Shelton, JM Zajecka, B Etemad, K Rickels, A Clain, ... American Journal of Psychiatry 169 (12), 1267-1274, 2012 | 336 | 2012 |
| Homocysteine and dementia: an international consensus statement AD Smith, H Refsum, T Bottiglieri, M Fenech, B Hooshmand, A McCaddon, ... Journal of Alzheimer's Disease 62 (2), 561-570, 2018 | 335 | 2018 |
| The clinical potential of ademetionine (S-adenosylmethionine) in neurological disorders T Bottiglieri, K Hyland, EH Reynolds Drugs 48 (2), 137-152, 1994 | 324 | 1994 |
| Cerebral vascular dysfunction mediated by superoxide in hyperhomocysteinemic mice S Dayal, E Arning, T Bottiglieri, RH Böger, CD Sigmund, FM Faraci, ... Stroke 35 (8), 1957-1962, 2004 | 276 | 2004 |
| Protein phosphatase 2A methyltransferase links homocysteine metabolism with tau and amyloid precursor protein regulation E Sontag, V Nunbhakdi-Craig, JM Sontag, R Diaz-Arrastia, E Ogris, ... Journal of Neuroscience 27 (11), 2751-2759, 2007 | 272 | 2007 |
| Endothelial Dysfunction and Elevation of S-Adenosylhomocysteine in Cystathionine β-Synthase–Deficient Mice S Dayal, T Bottiglieri, E Arning, N Maeda, MR Malinow, CD Sigmund, ... Circulation research 88 (11), 1203-1209, 2001 | 257 | 2001 |
| Elevated prenatal homocysteine levels as a risk factor for schizophrenia AS Brown, T Bottiglieri, CA Schaefer, CP Quesenberry, L Liu, ... Archives of general psychiatry 64 (1), 31-39, 2007 | 235 | 2007 |
| Elevation of homocysteine and excitatory amino acid neurotransmitters in the CSF of children who receive methotrexate for the treatment of cancer CT Quinn, JC Griener, T Bottiglieri, K Hyland, A Farrow, BA Kamen Journal of Clinical Oncology 15 (8), 2800-2806, 1997 | 234 | 1997 |
| Betaine improves nonalcoholic fatty liver and associated hepatic insulin resistance: a potential mechanism for hepatoprotection by betaine E Kathirvel, K Morgan, G Nandgiri, BC Sandoval, MA Caudill, T Bottiglieri, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 299 (5 …, 2010 | 218 | 2010 |
