Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial S Hagel, F Bach, T Brenner, H Bracht, A Brinkmann, T Annecke, A Hohn, ... Intensive Care Medicine 48 (3), 311-321, 2022 | 106 | 2022 |
The effect of renal replacement therapy and antibiotic dose on antibiotic concentrations in critically ill patients: data from the multinational sampling antibiotics in renal … JA Roberts, GM Joynt, A Lee, G Choi, R Bellomo, S Kanji, MY Mudaliar, ... Clinical Infectious Diseases 72 (8), 1369-1378, 2021 | 103 | 2021 |
Emergence of ceftazidime/avibactam non-susceptibility in an MDR Klebsiella pneumoniae isolate A Both, H Büttner, J Huang, M Perbandt, C Belmar Campos, M Christner, ... Journal of Antimicrobial Chemotherapy 72 (9), 2483-2488, 2017 | 98 | 2017 |
Carbapenem-resistant Gram-negative pathogens in a German university medical center: Prevalence, clinical implications and the role of novel β-lactam/β-lactamase inhibitor … J Katchanov, L Asar, EM Klupp, A Both, C Rothe, C König, H Rohde, ... PLoS One 13 (4), e0195757, 2018 | 71 | 2018 |
In vitro removal of anti-infective agents by a novel cytokine adsorbent system C König, AC Röhr, OR Frey, A Brinkmann, JA Roberts, D Wichmann, ... The International Journal of Artificial Organs 42 (2), 57-64, 2019 | 67 | 2019 |
Pharmacokinetics of meropenem in septic patients on sustained low-efficiency dialysis: a population pharmacokinetic study S Braune, C König, JA Roberts, A Nierhaus, O Steinmetz, M Baehr, ... Critical Care 22, 1-10, 2018 | 34 | 2018 |
Population pharmacokinetics of vancomycin in critically ill patients receiving prolonged intermittent renal replacement therapy CJP Economou, JT Kielstein, D Czock, J Xie, J Field, B Richards, M Tallott, ... International journal of antimicrobial agents 52 (2), 151-157, 2018 | 31 | 2018 |
Tedizolid susceptibility in linezolid- and vancomycin-resistant Enterococcus faecium isolates EM Klupp, A Both, C Belmar Campos, H Büttner, C König, M Christopeit, ... European Journal of Clinical Microbiology & Infectious Diseases 35, 1957-1961, 2016 | 28 | 2016 |
Population pharmacokinetics and dosing simulations of ceftazidime in critically ill patients receiving sustained low-efficiency dialysis C König, S Braune, JA Roberts, A Nierhaus, OM Steinmetz, M Baehr, ... Journal of Antimicrobial Chemotherapy 72 (5), 1433-1440, 2017 | 24 | 2017 |
Intrathecal penetration of meropenem and vancomycin administered by continuous infusion in patients suffering from ventriculitis—a retrospective analysis MMD Mader, P Czorlich, C König, V Fuhrmann, S Kluge, M Westphal, ... Acta Neurochirurgica 160, 2099-2105, 2018 | 21 | 2018 |
Cefiderocol in critically ill patients with multi-drug resistant pathogens: real-life data on pharmacokinetics and microbiological surveillance C König, A Both, H Rohde, S Kluge, OR Frey, AC Röhr, D Wichmann Antibiotics 10 (6), 649, 2021 | 18 | 2021 |
Acute-on-chronic liver failure alters meropenem pharmacokinetics in critically ill patients with continuous hemodialysis: an observational study J Grensemann, D Busse, C König, K Roedl, W Jäger, D Jarczak, ... Annals of Intensive Care 10, 1-10, 2020 | 14 | 2020 |
Adequate anti-infective treatment : Importance of individual dosing and application A Brinkmann, AC Röhr, A Köberer, T Fuchs, WA Krüger, C König, ... Der Anaesthesist 67 (6), 461-476, 2018 | 13 | 2018 |
Fragen und Antworten zur individuellen Dosierung von ß-Lactam-Antibiotika bei kritisch Kranken OR Frey, S Helbig, AC Röhr, J Preisenberger, A Köberer, T Fuchs, ... Intensiv-News 19 (4), 30-3, 2015 | 12 | 2015 |
Pretomanid-resistant tuberculosis N Koehler, S Andres, M Merker, V Dreyer, A John, M Kuhns, D Krieger, ... Journal of Infection 86 (5), 520-524, 2023 | 9 | 2023 |
A dosing nomograph for cerebrospinal fluid penetration of meropenem applied by continuous infusion in patients with nosocomial ventriculitis C König, J Grensemann, P Czorlich, E Schlemm, S Kluge, SG Wicha Clinical Microbiology and Infection, 2022 | 7 | 2022 |
Validation and application of an HPLC-UV method for routine therapeutic drug monitoring of cefiderocol J Zimmer, AC Röhr, S Kluge, J Faller, OR Frey, D Wichmann, C König Antibiotics 10 (3), 242, 2021 | 7 | 2021 |
The impact of pharmacists’ interventions within the closed loop medication management process on medication safety: an analysis in a German university hospital V Berger, C Sommer, P Boje, J Hollmann, J Hummelt, C König, S Lezius, ... Frontiers in Pharmacology 13, 1030406, 2022 | 5 | 2022 |
Risk factors for excessively prolonged meropenem use in the intensive care setting: a case-control study J Katchanov, B Kreuels, FP Maurer, K Wöstmann, J Jochum, C König, ... BMC Infectious Diseases 17, 1-7, 2017 | 5 | 2017 |
Ciprofloxacin in patients undergoing extracorporeal membrane oxygenation (ECMO): a population pharmacokinetic study D Alihodzic, SG Wicha, OR Frey, C König, M Baehr, D Jarczak, S Kluge, ... Pharmaceutics 14 (5), 965, 2022 | 4 | 2022 |