Anne Grosse-Wilde
Anne Grosse-Wilde
Seattle Genetics
Bestätigte E-Mail-Adresse bei
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Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8
MR Sprick, E Rieser, H Stahl, A Grosse-Wilde, MA Weigand, H Walczak
The EMBO journal 21 (17), 4520-4530, 2002
Stemness of the hybrid epithelial/mesenchymal state in breast cancer and its association with poor survival
A Grosse-Wilde, A Fouquier d’Hérouël, E McIntosh, G Ertaylan, A Skupin, ...
PloS one 10 (5), e0126522, 2015
Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by …
TM Ganten, TL Haas, J Sykora, H Stahl, MR Sprick, SC Fas, A Krueger, ...
Cell Death & Differentiation 11 (1), S86-S96, 2004
TRAIL-R deficiency in mice enhances lymph node metastasis without affecting primary tumor development
A Grosse-Wilde, O Voloshanenko, SL Bailey, GM Longton, U Schaefer, ...
The Journal of clinical investigation 118 (1), 2007
Cancer cell-autonomous TRAIL-R signaling promotes KRAS-driven cancer progression, invasion, and metastasis
S von Karstedt, A Conti, M Nobis, A Montinaro, T Hartwig, J Lemke, ...
Cancer cell 27 (4), 561-573, 2015
TNF-related apoptosis-inducing ligand mediates tumoricidal activity of human monocytes stimulated by Newcastle disease virus
B Washburn, MA Weigand, A Grosse-Wilde, M Janke, H Stahl, E Rieser, ...
The Journal of Immunology 170 (4), 1814-1821, 2003
Different mitogen-activated protein kinase signaling pathways cooperate to regulate tumor necrosis factor α gene expression in T lymphocytes
A Hoffmeyer, A Grosse-Wilde, E Flory, B Neufeld, M Kunz, UR Rapp, ...
Journal of Biological Chemistry 274 (7), 4319-4327, 1999
Pharmacokinetics of intrathecally applied BDNF and effects on spinal motoneurons
F Dittrich, G Ochs, A Große-Wilde, U Berweiler, Q Yan, JA Miller, ...
Experimental neurology 141 (2), 225-239, 1996
Serine/Threonine kinases 3pK and MAPK-activated protein kinase 2 interact with the basic helix-loop-helix transcription factor E47 and repress its transcriptional activity
B Neufeld, A Grosse-Wilde, A Hoffmeyer, BWM Jordan, P Chen, D Dinev, ...
Journal of Biological Chemistry 275 (27), 20239-20242, 2000
Transforming growth factor β can mediate apoptosis via the expression of TRAIL in human hepatoma cells
K Herzer, TM Ganten, H Schulze‐Bergkamen, A Grosse‐Wilde, ...
Hepatology 42 (1), 183-192, 2005
Transforming Growth Factor-β–Mediated Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Expression and Apoptosis in Hepatoma Cells Requires Functional Cooperation between …
K Herzer, A Grosse-Wilde, PH Krammer, PR Galle, S Kanzler
Molecular Cancer Research 6 (7), 1169-1177, 2008
Metastasis Suppressor Function of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand-R in Mice: Implications for TRAIL-Based Therapy in Humans?
A Grosse-Wilde, CJ Kemp
Cancer research 68 (15), 6035-6037, 2008
Loss of inter-cellular cooperation by complete epithelial-mesenchymal transition supports favorable outcomes in basal breast cancer patients
A Grosse-Wilde, RE Kuestner, SM Skelton, E MacIntosh, AF d’Hérouël, ...
Oncotarget 9 (28), 20018, 2018
323 Systemic administration of ladiratuzumab vedotin alone or in combination with pembrolizumab results in significant immune activation in the tumor microenvironment in …
L Pusztai, H Lu, C Hale, A Grosse-Wilde, J Specht, S Modi, H Han, ...
Journal for ImmunoTherapy of Cancer 8 (Suppl 3), 2020
SGN-B6A: A new MMAE ADC targeting integrin beta-6 in multiple carcinoma indications
RP Lyon, MW Schmitt, M Jonas, C Frantz, E Trueblood, R Yumul, ...
Nat. Rev. Cancer 10 (1), 9-22, 2010
Post-treatment biopsies show evidence of cell cycle arrest and immune cell infiltration into tumors of ladiratuzumab vedotin-treated advanced breast cancer patients
J Specht, L Pusztai, A Forero-Torres, M Mita, A Weise, I Krop, ...
Annals of Oncology 29, viii92, 2018
Different MAPK signaling pathways cooperate to regulate TNFα gene expression in T lymphocyte
A Hoffmeyer
J Biol Chem 274, 4319-4327, 1999
281 TGF-β is involved in the regulation of apoptosis via trail expression in hepatoma cells
K Herzer, A Grosse-Wilde, T Gantrn, H Walczak, PH Krammer
Journal of Hepatology, 87, 2004
Abstract LB-045: A tissue-engineered vascularized tumor microenvironment for preclinical testing of anticancer therapeutics
H Mann, A Grosse-Wilde
Cancer Research 76 (14_Supplement), LB-045-LB-045, 2016
Synergy between epithelial and mesenchymal cells in breast cancer: from mammospheres to predicting patient outcomes
A Grosse-Wilde, A d'Herouel, R Kuestner, G Ertaylan, A Skupin, S Huang, ...
Cancer Research 74 (19_Supplement), 1918-1918, 2014
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