Daniel Huebschmann
Daniel Huebschmann
Clinician scientist, junior group leader German Cancer Research Center (DKFZ) and Heidelberg Institute of Stem Cell Technology and Experimental Medicine (HI-STEM)
Verified email at dkfz-heidelberg.de - Homepage
TitleCited byYear
The whole-genome landscape of medulloblastoma subtypes
PA Northcott, I Buchhalter, AS Morrissy, V Hovestadt, J Weischenfeldt, ...
Nature 547 (7663), 311, 2017
2162017
The landscape of genomic alterations across childhood cancers
SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ...
Nature 555 (7696), 321, 2018
2012018
Precision oncology based on omics data: the NCT Heidelberg experience
P Horak, B Klink, C Heining, S Gröschel, B Hutter, M Fröhlich, S Uhrig, ...
International journal of cancer 141 (5), 877-886, 2017
412017
Integration of genomics and histology revises diagnosis and enables effective therapy of refractory cancer of unknown primary with PDL1 amplification
S Gröschel, M Bommer, B Hutter, J Budczies, D Bonekamp, C Heining, ...
Molecular Case Studies 2 (6), a001180, 2016
332016
Integrative genomic and transcriptomic analysis of leiomyosarcoma
P Chudasama, SS Mughal, MA Sanders, D Hübschmann, I Chung, ...
Nature communications 9 (1), 144, 2018
322018
Genetic subclone architecture of tumor clone-initiating cells in colorectal cancer
KM Giessler, K Kleinheinz, D Huebschmann, GP Balasubramanian, ...
Journal of Experimental Medicine 214 (7), 2073-2088, 2017
172017
Molecular evolution of early-onset prostate cancer identifies molecular risk markers and clinical trajectories
C Gerhauser, F Favero, T Risch, R Simon, L Feuerbach, Y Assenov, ...
Cancer Cell 34 (6), 996-1011. e8, 2018
162018
Spatial niche formation but not malignant progression is a driving force for intratumoural heterogeneity
R Hoefflin, B Lahrmann, G Warsow, D Hübschmann, C Spath, B Walter, ...
Nature communications 7, ncomms11845, 2016
142016
Mutant KIT as imatinib-sensitive target in metastatic sinonasal carcinoma
SM Dieter, C Heining, A Agaimy, D Huebschmann, D Bonekamp, B Hutter, ...
Annals of Oncology 28 (1), 142-148, 2017
132017
Evolutionary trajectories of IDHWT glioblastomas reveal a common path of early tumorigenesis instigated years ahead of initial diagnosis
V Körber, J Yang, P Barah, Y Wu, D Stichel, Z Gu, MNC Fletcher, D Jones, ...
Cancer cell 35 (4), 692-704. e12, 2019
122019
Whole genome sequencing puts forward hypotheses on metastasis evolution and therapy in colorectal cancer
N Ishaque, ML Abba, C Hauser, N Patil, N Paramasivam, ...
Nature communications 9 (1), 4782, 2018
102018
Newborn screening for severe combined immunodeficiency using a novel and simplified method to measure T-cell excision circles (TREC)
L Tagliaferri, JB Kunz, M Happich, S Esposito, T Bruckner, ...
Clinical Immunology 175, 51-55, 2017
102017
ICGC PedBrain-Seq Project ICGC MMML-Seq Project
SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ...
The landscape of genomic alterations across childhood cancers. Nature 555 …, 2018
72018
ACEseq-allele specific copy number estimation from whole genome sequencing
K Kleinheinz, I Bludau, D Huebschmann, M Heinold, P Kensche, Z Gu, ...
BioRxiv, 210807, 2017
72017
Defective homologous recombination DNA repair as therapeutic target in advanced chordoma
S Gröschel, D Hübschmann, F Raimondi, P Horak, G Warsow, M Fröhlich, ...
Nature communications 10 (1), 1635, 2019
62019
Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma
C López, K Kleinheinz, SM Aukema, M Rohde, SH Bernhart, ...
Nature communications 10 (1), 1459, 2019
62019
IG-MYC+ neoplasms with precursor B-cell phenotype are molecularly distinct from Burkitt lymphomas
R Wagener, C López, K Kleinheinz, J Bausinger, SM Aukema, I Nagel, ...
Blood 132 (21), 2280-2285, 2018
62018
The mutational landscape of Burkitt-like lymphoma with 11q aberration is distinct from that of Burkitt lymphoma
R Wagener, J Seufert, F Raimondi, S Bens, K Kleinheinz, I Nagel, ...
Blood 133 (9), 962-966, 2019
52019
YAPSA: Yet Another Package for Signature Analysis
D Hübschmann, Z Gu, M Schlesner
R package version 1 (0), 2015
52015
Correction: The landscape of genomic alterations across childhood cancers (Nature (2018
SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ...
Nature 559 (7714), E10, 2018
42018
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