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Ayse Ulusoy
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Caudo‐rostral brain spreading of α‐synuclein through vagal connections
A Ulusoy, R Rusconi, BI Pérez‐Revuelta, RE Musgrove, M Helwig, ...
EMBO molecular medicine 5 (7), 1119-1127, 2013
2962013
α-Synuclein expression and Nrf2 deficiency cooperate to aggravate protein aggregation, neuronal death and inflammation in early-stage Parkinson's disease
I Lastres-Becker, A Ulusoy, NG Innamorato, G Sahin, A Rábano, D Kirik, ...
Human molecular genetics 21 (14), 3173-3192, 2012
2802012
GDNF fails to exert neuroprotection in a rat α-synuclein model of Parkinson’s disease
M Decressac, A Ulusoy, B Mattsson, B Georgievska, M Romero-Ramos, ...
Brain 134 (8), 2302-2311, 2011
2222011
Brain-to-stomach transfer of α-synuclein via vagal preganglionic projections
A Ulusoy, RJ Phillips, M Helwig, M Klinkenberg, TL Powley, DA Di Monte
Acta neuropathologica 133, 381-393, 2017
1862017
Oxidative stress in vagal neurons promotes parkinsonian pathology and intercellular α-synuclein transfer
RE Musgrove, M Helwig, EJ Bae, H Aboutalebi, SJ Lee, A Ulusoy, ...
The Journal of clinical investigation 129 (9), 3738-3753, 2019
1672019
Viral vector-mediated overexpression of α-synuclein as a progressive model of Parkinson’s disease
A Ulusoy, M Decressac, D Kirik, A Björklund
Progress in brain research 184, 89-111, 2010
1562010
LRRK2 kinase regulates α-synuclein propagation via RAB35 phosphorylation
EJ Bae, DK Kim, C Kim, M Mante, A Adame, E Rockenstein, A Ulusoy, ...
Nature communications 9 (1), 3465, 2018
1462018
Co‐expression of C‐terminal truncated alpha‐synuclein enhances full‐length alpha‐synuclein‐induced pathology
A Ulusoy, F Febbraro, PH Jensen, D Kirik, M Romero‐Ramos
European Journal of Neuroscience 32 (3), 409-422, 2010
1282010
Activation of the DNA damage response in vivo in synucleinopathy models of Parkinson’s disease
C Milanese, S Cerri, A Ulusoy, SV Gornati, A Plat, S Gabriels, F Blandini, ...
Cell death & disease 9 (8), 818, 2018
1162018
Brain propagation of transduced α-synuclein involves non-fibrillar protein species and is enhanced in α-synuclein null mice
M Helwig, M Klinkenberg, R Rusconi, RE Musgrove, NK Majbour, ...
Brain 139 (3), 856-870, 2016
1092016
Neuron-to-neuron α-synuclein propagation in vivo is independent of neuronal injury
A Ulusoy, RE Musgrove, R Rusconi, M Klinkenberg, M Helwig, ...
Acta neuropathologica communications 3, 1-13, 2015
1062015
Phosphorylation of Parkin at serine 65 is essential for its activation in vivo
TG McWilliams, E Barini, R Pohjolan-Pirhonen, SP Brooks, F Singh, ...
Royal Society Open Biology 8 (11), 180108, 2018
1052018
Dose optimization for long-term rAAV-mediated RNA interference in the nigrostriatal projection neurons
A Ulusoy, G Sahin, T Björklund, P Aebischer, D Kirik
Molecular Therapy 17 (9), 1574-1584, 2009
952009
In vivo models of alpha-synuclein transmission and propagation
A Recasens, A Ulusoy, PJ Kahle, DA Di Monte, B Dehay
Cell and tissue research 373, 183-193, 2018
722018
Synapsin condensates recruit alpha-synuclein
C Hoffmann, R Sansevrino, G Morabito, C Logan, RM Vabulas, A Ulusoy, ...
Journal of molecular biology 433 (12), 166961, 2021
682021
Dysregulated dopamine storage increases the vulnerability to α-synuclein in nigral neurons
A Ulusoy, T Björklund, K Buck, D Kirik
Neurobiology of disease 47 (3), 367-377, 2012
682012
Presynaptic dopaminergic compartment determines the susceptibility to L-DOPA–induced dyskinesia in rats
A Ulusoy, G Sahin, D Kirik
Proceedings of the National Academy of Sciences 107 (29), 13159-13164, 2010
632010
α-Synuclein elevation in human neurodegenerative diseases: experimental, pathogenetic, and therapeutic implications
A Ulusoy, DA Di Monte
Molecular neurobiology 47, 484-494, 2013
622013
Animal models of brain-first and body-first Parkinson's disease
N Van Den Berge, A Ulusoy
Neurobiology of disease 163, 105599, 2022
532022
In vivo gene delivery for development of mammalian models for Parkinson's disease
A Ulusoy, T Bjorklund, S Hermening, D Kirik
Experimental neurology 209 (1), 89-100, 2008
522008
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