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Justina Šileikytė
Justina Šileikytė
Senior Research Associate, Oregon Heath and Science University
Bestätigte E-Mail-Adresse bei ohsu.edu
Titel
Zitiert von
Zitiert von
Jahr
Regulation of the mitochondrial permeability transition pore by the outer membrane does not involve the peripheral benzodiazepine receptor (Translocator Protein of 18 kDa (TSPO))
J Sileikytė, E Blachly-Dyson, R Sewell, A Carpi, R Menabò, F Di Lisa, ...
Journal of Biological Chemistry 289 (20), 13769-13781, 2014
2122014
Channel Formation by Yeast F-ATP Synthase and the Role of Dimerization in the Mitochondrial Permeability Transition
M Carraro, V Giorgio, J Šileikytė, G Sartori, M Forte, G Lippe, M Zoratti, ...
Biochimica et Biophysica Acta (BBA) - Bioenergetics 1837 (supplement), e12, 2014
1822014
Regulation of the inner membrane mitochondrial permeability transition by the outer membrane translocator protein (peripheral benzodiazepine receptor)
J Šileikytė, V Petronilli, A Zulian, F Dabbeni-Sala, G Tognon, P Nikolov, ...
Journal of Biological Chemistry 286 (2), 1046-1053, 2011
1332011
Shedding light on the mitochondrial permeability transition
F Ricchelli, J Šileikytė, P Bernardi
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1807 (5), 482-490, 2011
1102011
The mitochondrial permeability transition in mitochondrial disorders
J Šileikytė, M Forte
Oxidative medicine and cellular longevity 2019, 2019
792019
Defining the molecular mechanisms of the mitochondrial permeability transition through genetic manipulation of F-ATP synthase
A Carrer, L Tommasin, J Šileikytė, F Ciscato, R Filadi, A Urbani, M Forte, ...
Nature communications 12 (1), 4835, 2021
622021
Discovery, synthesis, and optimization of diarylisoxazole‐3‐carboxamides as potent inhibitors of the mitochondrial permeability transition pore
S Roy, J Šileikytė, M Schiavone, B Neuenswander, F Argenton, J Aubé, ...
ChemMedChem 10 (10), 1655-1671, 2015
492015
Switch from inhibition to activation of the mitochondrial permeability transition during hematoporphyrin-mediated photooxidative stress.: Unmasking pore-regulating external thiols
V Petronilli, J Šileikytė, A Zulian, F Dabbeni-Sala, G Jori, S Gobbo, ...
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1787 (7), 897-904, 2009
462009
N‐Phenylbenzamides as Potent Inhibitors of the Mitochondrial Permeability Transition Pore
S Roy, J Šileikytė, B Neuenswander, MP Hedrick, TDY Chung, J Aubé, ...
ChemMedChem 11 (3), 283-288, 2016
422016
Shutting down the pore: The search for small molecule inhibitors of the mitochondrial permeability transition
J Šileikytė, M Forte
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1857 (8), 1197-1202, 2016
392016
A novel class of cardioprotective small-molecule PTP inhibitors
S Antonucci, M Di Sante, J Sileikyte, J Deveraux, T Bauer, MJ Bround, ...
Pharmacological research 151, 104548, 2020
262020
Second‐generation inhibitors of the mitochondrial permeability transition pore with improved plasma stability
J Šileikytė, J Devereaux, J de Jong, M Schiavone, K Jones, A Nilsen, ...
ChemMedChem 14 (20), 1771-1782, 2019
222019
Treatment with a triazole inhibitor of the mitochondrial permeability transition pore fully corrects the pathology of sapje zebrafish lacking dystrophin
A Stocco, N Smolina, P Sabatelli, J Šileikytė, E Artusi, V Mouly, M Cohen, ...
Pharmacological Research 165, 105421, 2021
212021
Chemical proteomics approach for profiling the NAD interactome
J Šileikytė, S Sundalam, LL David, MS Cohen
Journal of the American Chemical Society 143 (18), 6787-6791, 2021
172021
The translocator protein (peripheral benzodiazepine receptor) mediates rat-selective activation of the mitochondrial permeability transition by norbormide
A Zulian, J Šileikytė, V Petronilli, S Bova, F Dabbeni-Sala, G Cargnelli, ...
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1807 (12), 1600-1605, 2011
172011
Small Molecules Targeting the Mitochondrial Permeability Transition
J Sileikyte, S Roy, P Porubsky, B Neuenswander, J Wang, M Hedrick, ...
Probe Reports from the NIH Molecular Libraries Program, 2014
142014
Small molecules targeting the mitochondrial permeability transition, In Probe Reports from the NIH Molecular Libraries Program
J Sileikyte, S Roy, P Porubsky, B Neuenswander, J Wang, M Hedrick, ...
National Center for Biotechnology Information,(US), Place Published, 2010
62010
Allosteric regulation of DNA binding and target residence time drive the cytotoxicity of phthalazinone-based PARP-1 inhibitors
MR Arnold, MF Langelier, J Gartrell, IT Kirby, DJ Sanderson, DS Bejan, ...
Cell Chemical Biology 29 (12), 1694-1708. e10, 2022
32022
Second generation inhibitors of mitochondrial permeability transition pore with improved plasma stability
M Cohen, M Forte, J Sileikyte, A Nilsen, J Devereaux, P Bernardi
US Patent App. 17/636,327, 2022
12022
Shedding light on the permeability transition through S. cerevisiae F-ATP synthase mutagenesis
M Carraro, L Guo, V Giorgio, V Checchetto, J Šileikytė, G Sartori, M Forte, ...
2016 EBEC Abstracts 1857, e62-e62, 2016
12016
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