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Lena Marie Berger
Lena Marie Berger
Bestätigte E-Mail-Adresse bei pharmchem.uni-frankfurt.de - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Design, synthesis, and evaluation of WD-repeat-containing protein 5 (WDR5) degraders
A Dölle, B Adhikari, A Krämer, J Weckesser, N Berner, LM Berger, ...
Journal of medicinal chemistry 64 (15), 10682-10710, 2021
212021
A highly selective chemical probe for activin receptor-like kinases ALK4 and ALK5
T Hanke, JF Wong, BT Berger, I Abdi, LM Berger, R Tesch, C Tredup, ...
ACS Chemical Biology 15 (4), 862-870, 2020
112020
Solution structures and biophysical analysis of full-length group A PAKs reveal they are monomeric and auto-inhibited in cis
FJ Sorrell, LM Kilian, JM Elkins
Biochemical Journal 476 (7), 1037-1051, 2019
92019
Structure-based design of selective salt-inducible kinase inhibitors
R Tesch, M Rak, M Raab, LM Berger, T Kronenberger, AC Joerger, ...
Journal of Medicinal Chemistry 64 (12), 8142-8160, 2021
72021
Design of a “two-in-one” mutant-selective epidermal growth factor receptor inhibitor that spans the orthosteric and allosteric sites
F Wittlinger, DE Heppner, C To, M Günther, BH Shin, JK Rana, ...
Journal of Medicinal Chemistry 65 (2), 1370-1383, 2021
62021
Inhibitors of the Hippo pathway kinases STK3/MST2 and STK4/MST1 have utility for the treatment of acute myeloid leukemia
N Bata, A Chaikuad, NA Bakas, AS Limpert, LJ Lambert, DJ Sheffler, ...
Journal of medicinal chemistry 65 (2), 1352-1369, 2021
52021
Illuminating the Dark: Highly Selective Inhibition of Serine/Threonine Kinase 17A with Pyrazolo[1,5-a]pyrimidine-Based Macrocycles
CG Kurz, F Preuss, A Tjaden, M Cusack, JA Amrhein, D Chatterjee, ...
Journal of Medicinal Chemistry 65 (11), 7799-7817, 2022
42022
A Toolbox for the Generation of Chemical Probes for Baculovirus IAP Repeat Containing Proteins
MP Schwalm, LM Berger, MN Meuter, JD Vasta, CR Corona, S Röhm, ...
Frontiers in Cell and Developmental Biology 10, 2022
22022
Single tracer-based protocol for broad-spectrum kinase profiling in live cells with NanoBRET
MB Robers, JM Wilkinson, JD Vasta, LM Berger, BT Berger, S Knapp
STAR protocols 2 (4), 100822, 2021
22021
C81‐evoked inhibition of the TNFR1‐NFκB pathway during inflammatory processes for stabilization of the impaired vascular endothelial barrier for leukocytes
GM Krishnathas, B Strödke, L Mittmann, T Zech, LM Berger, CA Reichel, ...
The FASEB Journal 35 (6), e21656, 2021
22021
Discovery of 3-Amino-1H-pyrazole-Based Kinase Inhibitors to Illuminate the Understudied PCTAIRE Family
JA Amrhein, LM Berger, A Tjaden, A Krämer, L Elson, T Tolvanen, ...
International Journal of Molecular Sciences 23 (23), 14834, 2022
2022
Pharmacokinetic Optimization of Small Molecule Janus Kinase 3 Inhibitors to Target Immune Cells
J Laux, M Forster, L Riexinger, A Schwamborn, J Guezguez, C Pokoj, ...
ACS Pharmacology & Translational Science 5 (8), 573-602, 2022
2022
First preclinical insights into the anti-angiogenic actions of C81
T Zech, I Bischoff-Kont, GM Krishnathas, L Berger, S Roesser, B Stroedke, ...
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 395 (SUPPL 1), S13-S13, 2022
2022
The carbazole derivative C81 provides promising anti-inflammatory and pro-resolving effects in leukocytes
S Ciurus, L Berger, B Stroedke, S Mueller, S Knapp, LD Burgers, ...
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 395 (SUPPL 1), S8-S9, 2022
2022
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