Shape complementarity at protein/protein interfaces MC Lawrence, PM Colman Journal of molecular biology 234 (4), 946-950, 1993 | 1520 | 1993 |
The structural biology of type I viral membrane fusion PM Colman, MC Lawrence Nature Reviews Molecular Cell Biology 4 (4), 309-319, 2003 | 601 | 2003 |
How insulin engages its primary binding site on the insulin receptor JG Menting, J Whittaker, MB Margetts, LJ Whittaker, GKW Kong, BJ Smith, ... Nature 493 (7431), 241-245, 2013 | 469 | 2013 |
A molecular mechanism for bacterial susceptibility to zinc CA McDevitt, AD Ogunniyi, E Valkov, MC Lawrence, B Kobe, AG McEwan, ... PLoS pathogens 7 (11), e1002357, 2011 | 458 | 2011 |
Insulin receptor isoforms in physiology and disease: an updated view A Belfiore, R Malaguarnera, V Vella, MC Lawrence, L Sciacca, F Frasca, ... Endocrine reviews 38 (5), 379-431, 2017 | 373 | 2017 |
Structure of the insulin receptor ectodomain reveals a folded-over conformation NM McKern, MC Lawrence, VA Streltsov, MZ Lou, TE Adams, GO Lovrecz, ... Nature 443 (7108), 218-221, 2006 | 358 | 2006 |
Sequence and structure alignment of paramyxovirus hemagglutinin-neuraminidase with influenza virus neuraminidase. PM Colman, PA Hoyne, MC Lawrence Journal of virology 67 (6), 2972-2980, 1993 | 338 | 1993 |
A designed ankyrin repeat protein evolved to picomolar affinity to Her2 C Zahnd, E Wyler, JM Schwenk, D Steiner, MC Lawrence, NM McKern, ... Journal of molecular biology 369 (4), 1015-1028, 2007 | 314 | 2007 |
Structure of Phaseolin at 2· 2 Å Resolution: Implications for a Common Vicilin/Legumin Structure and the Genetic Engineering of Seed Storage Proteins MC Lawrence, T Izard, M Beuchat, RJ Blagrove, PM Colman Journal of molecular biology 238 (5), 748-776, 1994 | 307 | 1994 |
The structure of the fusion glycoprotein of Newcastle disease virus suggests a novel paradigm for the molecular mechanism of membrane fusion L Chen, JJ Gorman, J McKimm-Breschkin, LJ Lawrence, PA Tulloch, ... Structure 9 (3), 255-266, 2001 | 281 | 2001 |
The crystal structure of pneumococcal surface antigen PsaA reveals a metal-binding site and a novel structure for a putative ABC-type binding protein MC Lawrence, PA Pilling, VC Epa, AM Berry, AD Ogunniyi, JC Paton Structure 6 (12), 1553-1561, 1998 | 275 | 1998 |
Structure of the haemagglutinin-neuraminidase from human parainfluenza virus type III MC Lawrence, NA Borg, VA Streltsov, PA Pilling, VC Epa, JN Varghese, ... Journal of molecular biology 335 (5), 1343-1357, 2004 | 261 | 2004 |
Ligand‐induced activation of the insulin receptor: a multi‐step process involving structural changes in both the ligand and the receptor CW Ward, MC Lawrence Bioessays 31 (4), 422-434, 2009 | 221 | 2009 |
The insulin and EGF receptor structures: new insights into ligand-induced receptor activation CW Ward, MC Lawrence, VA Streltsov, TE Adams, NM McKern Trends in biochemical sciences 32 (3), 129-137, 2007 | 215 | 2007 |
Insulin receptor structure and its implications for the IGF-1 receptor MC Lawrence, NM McKern, CW Ward Current opinion in structural biology 17 (6), 699-705, 2007 | 206 | 2007 |
A method for monitoring the collapse of plastic sections as a function of electron dose PK Luther, MC Lawrence, RA Crowther Ultramicroscopy 24 (1), 7-18, 1988 | 204 | 1988 |
The three‐dimensional structure of the seed storage protein phaseolin at 3 A resolution. MC Lawrence, E Suzuki, JN Varghese, PC Davis, A Van Donkelaar, ... The EMBO journal 9 (1), 9-15, 1990 | 200 | 1990 |
CLIX: A search algorithm for finding novel ligands capable of binding proteins of known three‐dimensional structure MC Lawrence, PC Davis Proteins: Structure, Function, and Bioinformatics 12 (1), 31-41, 1992 | 195 | 1992 |
Protective hinge in insulin opens to enable its receptor engagement JG Menting, Y Yang, SJ Chan, NB Phillips, BJ Smith, J Whittaker, ... Proceedings of the National Academy of Sciences 111 (33), E3395-E3404, 2014 | 175 | 2014 |
Recombinant anti‐sialidase single‐chain variable fragment antibody: Characterization, formation of dimer and higher‐molecular‐mass multimers and the solution of the crystal … AA Kortt, RL Malby, JB Caldwell, LC Gruen, N Ivancic, MC Lawrence, ... European journal of biochemistry 221 (1), 151-157, 1994 | 162 | 1994 |