| Structural stability of SARS-CoV-2 3CLpro and identification of quercetin as an inhibitor by experimental screening O Abian, D Ortega-Alarcon, A Jimenez-Alesanco, L Ceballos-Laita, ... International journal of biological macromolecules 164, 1693-1703, 2020 | 244 | 2020 |
| Catalytic efficiency and vitality of HIV-1 proteases from African viral subtypes A Velazquez-Campoy, MJ Todd, S Vega, E Freire Proceedings of the National Academy of Sciences 98 (11), 6062-6067, 2001 | 193 | 2001 |
| Identification of a drug targeting an intrinsically disordered protein involved in pancreatic adenocarcinoma JL Neira, J Bintz, M Arruebo, B Rizzuti, T Bonacci, S Vega, A Lanas, ... Scientific reports 7 (1), 39732, 2017 | 129 | 2017 |
| Effects of melatonin implants during non‐breeding season on sperm motility and reproductive parameters in Rasa Aragonesa rams A Casao, S Vega, I Palacín, R Pérez‐Pe, A Laviña, FJ Quintín, E Sevilla, ... Reproduction in domestic animals 45 (3), 425-432, 2010 | 127 | 2010 |
| Amplification of the effects of drug resistance mutations by background polymorphisms in HIV-1 protease from African subtypes A Velazquez-Campoy, S Vega, E Freire Biochemistry 41 (27), 8613-8619, 2002 | 121 | 2002 |
| Thermodynamic rules for the design of high affinity HIV-1 protease inhibitors with adaptability to mutations and high selectivity towards unwanted targets H Ohtaka, S Muzammil, A Schön, A Velazquez-Campoy, S Vega, E Freire The international journal of biochemistry & cell biology 36 (9), 1787-1799, 2004 | 96 | 2004 |
| A unified framework based on the binding polynomial for characterizing biological systems by isothermal titration calorimetry S Vega, O Abian, A Velazquez-Campoy Methods 76, 99-115, 2015 | 85 | 2015 |
| Structural and thermodynamic basis of resistance to HIV-1 protease inhibition: implications for inhibitor design A Velazquez-Campoy, S Muzammil, H Ohtaka, A Schon, S Vega, E Freire Current Drug Targets-Infectious Disorders 3 (4), 311-328, 2003 | 81 | 2003 |
| A structural and thermodynamic escape mechanism from a drug resistant mutation of the HIV‐1 protease S Vega, LW Kang, A Velazquez‐Campoy, Y Kiso, LM Amzel, E Freire Proteins: Structure, Function, and Bioinformatics 55 (3), 594-602, 2004 | 79 | 2004 |
| A look at ligand binding thermodynamics in drug discovery R Claveria-Gimeno, S Vega, O Abian, A Velazquez-Campoy Expert Opinion on Drug Discovery 12 (4), 363-377, 2017 | 76 | 2017 |
| On the link between conformational changes, ligand binding and heat capacity S Vega, O Abian, A Velazquez-Campoy Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (5), 868-878, 2016 | 68 | 2016 |
| Protease inhibition in African subtypes of HIV-1 A Velázquez-Campoy, S Vega, E Fleming, U Bacha, Y Sayed, HW Dirr, ... Aids Rev 5 (3), 165-171, 2003 | 63 | 2003 |
| Rutin is a low micromolar inhibitor of SARS-CoV-2 main protease 3CLpro: Implications for drug design of quercetin analogs B Rizzuti, F Grande, F Conforti, A Jimenez-Alesanco, L Ceballos-Laita, ... Biomedicines 9 (4), 375, 2021 | 61 | 2021 |
| Seleno-Functionalization of Quercetin Improves the Non-Covalent Inhibition of Mpro and Its Antiviral Activity in Cells against SARS-CoV-2 F Mangiavacchi, P Botwina, E Menichetti, L Bagnoli, O Rosati, F Marini, ... International journal of molecular sciences 22 (13), 7048, 2021 | 55 | 2021 |
| Deconvolution analysis for classifying gastric adenocarcinoma patients based on differential scanning calorimetry serum thermograms S Vega, MA Garcia-Gonzalez, A Lanas, A Velazquez-Campoy, O Abian Scientific reports 5, 7988, 2015 | 52 | 2015 |
| Allosteric inhibitors of the NS3 protease from the hepatitis C virus O Abian, S Vega, J Sancho, A Velazquez-Campoy PLoS One 8 (7), e69773, 2013 | 44 | 2013 |
| Conformational stability of hepatitis C virus NS3 protease O Abian, S Vega, JL Neira, A Velazquez-Campoy Biophysical journal 99 (11), 3811-3820, 2010 | 35 | 2010 |
| The intervening domain from MeCP2 enhances the DNA affinity of the methyl binding domain and provides an independent DNA interaction site R Claveria-Gimeno, PM Lanuza, I Morales-Chueca, OC Jorge-Torres, ... Scientific Reports 7 (1), 41635, 2017 | 32 | 2017 |
| Isothermal titration calorimetry M Bastos, O Abian, CM Johnson, F Ferreira-da-Silva, S Vega, ... Nature Reviews Methods Primers 3 (1), 17, 2023 | 27 | 2023 |
| Thermal liquid biopsy for monitoring melanoma patients under surveillance during treatment: A pilot study A Velazquez-Campoy, S Vega, O Sanchez-Gracia, A Lanas, A Rodrigo, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1862 (8), 1701-1710, 2018 | 26 | 2018 |
