Kathleen Sprouffske
Kathleen Sprouffske
Novartis Institutes for BioMedical Research
Verified email at ieu.uzh.ch - Homepage
Cited by
Cited by
Growthcurver: an R package for obtaining interpretable metrics from microbial growth curves
K Sprouffske, A Wagner
BMC bioinformatics 17 (1), 1-4, 2016
Fast NMDA Receptor–Mediated Synaptic Currents in Neurons From Mice Lacking the ε2 (NR2B) Subunit
KR Tovar, K Sprouffske, GL Westbrook
Journal of neurophysiology 83 (1), 616-620, 2000
Cancer in light of experimental evolution
K Sprouffske, LMF Merlo, PJ Gerrish, CC Maley, PD Sniegowski
Current Biology 22 (17), R762-R771, 2012
Animal cell differentiation patterns suppress somatic evolution
JW Pepper, K Sprouffske, CC Maley
PLoS Comput Biol 3 (12), e250, 2007
Accurate reconstruction of the temporal order of mutations in neoplastic progression
K Sprouffske, JW Pepper, CC Maley
Cancer prevention research 4, 1135-1144, 2011
Solving the puzzle of metastasis: the evolution of cell migration in neoplasms
J Chen, K Sprouffske, Q Huang, CC Maley
PloS one 6 (4), e17933, 2011
High mutation rates limit evolutionary adaptation in Escherichia coli
K Sprouffske, J Aguilar-Rodríguez, P Sniegowski, A Wagner
PLoS genetics 14 (4), e1007324, 2018
An evolutionary explanation for the presence of cancer nonstem cells in neoplasms
K Sprouffske, C Athena Aktipis, JP Radich, M Carroll, AM Nedelcu, ...
Evolutionary applications 6 (1), 92-101, 2013
The SIB Swiss Institute of Bioinformatics’ resources: focus on curated databases
SIB Swiss Institute of Bioinformatics Members
Nucleic acids research 44 (D1), D27-D37, 2016
Peto's paradox revisited: theoretical evolutionary dynamics of cancer in wild populations
B Roche, K Sprouffske, H Hbid, D Misse, F Thomas
Evolutionary applications 6 (1), 109-116, 2013
Assessing the benefits of horizontal gene transfer by laboratory evolution and genome sequencing
HY Chu, K Sprouffske, A Wagner
BMC evolutionary biology 18 (1), 54, 2018
PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma
M Bleu, S Gaulis, R Lopes, K Sprouffske, V Apfel, S Holwerda, ...
Nature communications 10 (1), 1-10, 2019
The role of recombination in evolutionary adaptation of Escherichia coli to a novel nutrient
HY Chu, K Sprouffske, A Wagner
Journal of evolutionary biology 30 (9), 1692-1711, 2017
How Archiving by Freezing Affects the Genome-Scale Diversity of Escherichia coli Populations
K Sprouffske, J Aguilar-Rodríguez, A Wagner
Genome biology and evolution 8 (5), 1290-1298, 2016
Genetic heterogeneity and clonal evolution during metastasis in breast cancer patient-derived tumor xenograft models
K Sprouffske, G Kerr, C Li, A Prahallad, R Rebmann, V Waehle, ...
Computational and structural biotechnology journal 18, 323-331, 2020
Effect of population size and mutation rate on the evolution of RNA sequences on an adaptive landscape determined by RNA folding
AR Vahdati, K Sprouffske, A Wagner
International journal of biological sciences 13 (9), 1138, 2017
Cooperation and cancer
K Sprouffske, CC Maley
Cancer Genome and Tumor Microenvironment, 471-485, 2010
Application of simultaneous selective pressures slows adaptation
LMF Merlo, K Sprouffske, TC Howard, KL Gardiner, AF Caulin, SM Blum, ...
Evolutionary applications 13 (7), 1615-1625, 2020
Searching for a Cancer-Proof Organism: It’s the Journey That Teaches You About the Destination
H Kokko, S Schindler, K Sprouffske
Ecology and Evolution of Cancer, 247-254, 2017
Expressed molecular barcoding coupled with single cell RNAseq enables a high resolution investigation into the evolution of drug tolerance.
JL Cotton, VK Radhakrishna, JE Diez, DA Ruddy, K Sprouffske, G Boulay, ...
CANCER RESEARCH 80 (21), 2020
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