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John F Hancock
John F Hancock
Bestätigte E-Mail-Adresse bei uth.tmc.edu
Titel
Zitiert von
Zitiert von
Jahr
All ras proteins are polyisoprenylated but only some are palmitoylated
JF Hancock, AI Magee, JE Childs, CJ Marshall
Cell 57 (7), 1167-1177, 1989
22991989
A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane
JF Hancock, H Paterson, CJ Marshall
Cell 63 (1), 133-139, 1990
14131990
Activation of Raf as a result of recruitment to the plasma membrane
SM Hancock JF, Stokoe D, Macdonald SG, Cadwallader K
Science 264, 1463-1467, 1994
12401994
Ras proteins: different signals from different locations
JF Hancock
Nature reviews Molecular cell biology 4 (5), 373-385, 2003
11002003
Lipid rafts: contentious only from simplistic standpoints
JF Hancock
Nature Reviews Molecular Cell Biology 7 (6), 456-462, 2006
9882006
Direct visualization of Ras proteins in spatially distinct cell surface microdomains
IA Prior, C Muncke, RG Parton, JF Hancock
Journal of Cell Biology 160 (2), 165-170, 2003
8942003
PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function
MM Hill, M Bastiani, R Luetterforst, M Kirkham, A Kirkham, SJ Nixon, ...
Cell 132 (1), 113-124, 2008
7962008
Signalling ballet in space and time
BN Kholodenko, JF Hancock, W Kolch
Nature reviews Molecular cell biology 11 (6), 414-426, 2010
7082010
A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins
JF Hancock, K Cadwaller, H Paterson, CJ Marshall
The EMBO Journal 10 (13), 4033-4039, 1991
6671991
GTP-dependent segregation of H-ras from lipid rafts is required for biological activity
IA Prior, A Harding, J Yan, J Sluimer, RG Parton, JF Hancock
Nature cell biology 3 (4), 368-375, 2001
6612001
Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase
J Yan, S Roy, A Apolloni, A Lane, JF Hancock
Journal of Biological Chemistry 273 (37), 24052-24056, 1998
6291998
Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains
S Roy, R Luetterforst, A Harding, A Apolloni, M Etheridge, E Stang, ...
Nature cell biology 1 (2), 98-105, 1999
6021999
Post‐translational processing of p21ras is two‐step and involves carboxyl‐methylation and carboxy‐terminal proteolysis.
L Gutierrez, AI Magee, CJ Marshall, JF Hancock
The EMBO journal 8 (4), 1093-1098, 1989
5861989
H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway
A Apolloni, IA Prior, M Lindsay, RG Parton, JF Hancock
Molecular and Cellular Biology 20 (7), 2475-2487, 2000
5702000
H-ras, K-ras, and inner plasma membrane raft proteins operate in nanoclusters with differential dependence on the actin cytoskeleton
SJ Plowman, C Muncke, RG Parton, JF Hancock
Proceedings of the National Academy of Sciences 102 (43), 15500-15505, 2005
5312005
Ultrastructural identification of uncoated caveolin-independent early endocytic vehicles
M Kirkham, A Fujita, R Chadda, SJ Nixon, TV Kurzchalia, DK Sharma, ...
The Journal of cell biology 168 (3), 465-476, 2005
5242005
The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product
C Calés, JF Hancock, CJ Marshall, A Hall
Nature 332 (6164), 548-551, 1988
4711988
Plasma membrane nanoswitches generate high-fidelity Ras signal transduction
T Tian, A Harding, K Inder, S Plowman, RG Parton, JF Hancock
Nature cell biology 9 (8), 905-914, 2007
4402007
Methylation and proteolysis are essential for efficient membrane binding of prenylated p21K‐ras (B).
JF Hancock, K Cadwallader, CJ Marshall
The EMBO journal 10 (3), 641-646, 1991
4021991
Lipid rafts and membrane traffic
MF Hanzal-Bayer, JF Hancock
FEBS letters 581 (11), 2098-2104, 2007
3882007
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