| Transcription factor interactions: selectors of positive or negative regulation from a single DNA element MI Diamond, JN Miner, SK Yoshinaga, KR Yamamoto Science 249 (4974), 1266-1272, 1990 | 1587 | 1990 |
| Propagation of tau misfolding from the outside to the inside of a cell B Frost, RL Jacks, MI Diamond Journal of biological chemistry 284 (19), 12845-12852, 2009 | 1347 | 2009 |
| Distinct tau prion strains propagate in cells and mice and define different tauopathies DW Sanders, SK Kaufman, SL DeVos, AM Sharma, H Mirbaha, A Li, ... Neuron 82 (6), 1271-1288, 2014 | 1014 | 2014 |
| Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds BB Holmes, SL DeVos, N Kfoury, M Li, R Jacks, K Yanamandra, ... Proceedings of the National Academy of Sciences 110 (33), E3138-E3147, 2013 | 857 | 2013 |
| Prion-like mechanisms in neurodegenerative diseases B Frost, MI Diamond Nature Reviews Neuroscience 11 (3), 155-159, 2010 | 830 | 2010 |
| Neuronal activity enhances tau propagation and tau pathology in vivo JW Wu, SA Hussaini, IM Bastille, GA Rodriguez, A Mrejeru, K Rilett, ... Nature neuroscience 19 (8), 1085-1092, 2016 | 686 | 2016 |
| Trans-cellular propagation of Tau aggregation by fibrillar species N Kfoury, BB Holmes, H Jiang, DM Holtzman, MI Diamond Journal of Biological Chemistry 287 (23), 19440-19451, 2012 | 644 | 2012 |
| Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo K Yanamandra, N Kfoury, H Jiang, TE Mahan, S Ma, SE Maloney, ... Neuron 80 (2), 402-414, 2013 | 608 | 2013 |
| Proteopathic tau seeding predicts tauopathy in vivo BB Holmes, JL Furman, TE Mahan, TR Yamasaki, H Mirbaha, WC Eades, ... Proceedings of the National Academy of sciences 111 (41), E4376-E4385, 2014 | 578 | 2014 |
| Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy SL DeVos, RL Miller, KM Schoch, BB Holmes, CS Kebodeaux, ... Science translational medicine 9 (374), eaag0481, 2017 | 430 | 2017 |
| Tau prion strains dictate patterns of cell pathology, progression rate, and regional vulnerability in vivo SK Kaufman, DW Sanders, TL Thomas, AJ Ruchinskas, J Vaquer-Alicea, ... Neuron 92 (4), 796-812, 2016 | 409 | 2016 |
| In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice K Yamada, JR Cirrito, FR Stewart, H Jiang, MB Finn, BB Holmes, ... Journal of Neuroscience 31 (37), 13110-13117, 2011 | 388 | 2011 |
| Polyglutamine diseases: emerging concepts in pathogenesis and therapy J Shao, MI Diamond Human molecular genetics 16 (R2), R115-R123, 2007 | 372 | 2007 |
| Mechanisms of protein seeding in neurodegenerative diseases LC Walker, MI Diamond, KE Duff, BT Hyman JAMA neurology 70 (3), 304-310, 2013 | 279 | 2013 |
| The structural basis of androgen receptor activation: Intramolecular and intermolecular amino–carboxy interactions F Schaufele, X Carbonell, M Guerbadot, S Borngraeber, MS Chapman, ... Proceedings of the National Academy of Sciences 102 (28), 9802-9807, 2005 | 271 | 2005 |
| Conformational diversity of wild-type Tau fibrils specified by templated conformation change B Frost, J Ollesch, H Wille, MI Diamond Journal of Biological Chemistry 284 (6), 3546-3551, 2009 | 261 | 2009 |
| Propagation of protein aggregation in neurodegenerative diseases J Vaquer-Alicea, MI Diamond Annual review of biochemistry 88, 785-810, 2019 | 249 | 2019 |
| Inert and seed-competent tau monomers suggest structural origins of aggregation H Mirbaha, D Chen, OA Morazova, KM Ruff, AM Sharma, X Liu, ... Elife 7, e36584, 2018 | 241 | 2018 |
| Propagation of prions causing synucleinopathies in cultured cells AL Woerman, J Stöhr, A Aoyagi, R Rampersaud, Z Krejciova, JC Watts, ... Proceedings of the National Academy of Sciences 112 (35), E4949-E4958, 2015 | 241 | 2015 |
| Tau trimers are the minimal propagation unit spontaneously internalized to seed intracellular aggregation H Mirbaha, BB Holmes, DW Sanders, J Bieschke, MI Diamond Journal of biological chemistry 290 (24), 14893-14903, 2015 | 239 | 2015 |
Brandon B. HolmesResearch and Clinical Fellow, UCSFVerified email at ucsf.edu
