Professor David C. Henshall
Professor David C. Henshall
Director, FutureNeuro, SFI Research Centre, RCSI
Bestätigte E-Mail-Adresse bei
Zitiert von
Zitiert von
Increased hippocampal neurogenesis in Alzheimer's disease
K Jin, AL Peel, XO Mao, L Xie, BA Cottrell, DC Henshall, DA Greenberg
Proceedings of the National Academy of Sciences 101 (1), 343-347, 2004
Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects
EM Jimenez-Mateos, T Engel, P Merino-Serrais, RC McKiernan, ...
Nature medicine 18 (7), 1087-1094, 2012
To die or not to die for neurons in ischemia, traumatic brain injury and epilepsy: a review on the stress-activated signaling pathways and apoptotic pathways
AKF Liou, RS Clark, DC Henshall, XM Yin, J Chen
Progress in neurobiology 69 (2), 103-142, 2003
Activation of Bcl-2-associated death protein and counter-response of Akt within cell populations during seizure-induced neuronal death
DC Henshall, T Araki, CK Schindler, JQ Lan, KL Tiekoter, W Taki, ...
Journal of Neuroscience 22 (19), 8458-8465, 2002
Neuroprotective actions of FK506 in experimental stroke: in vivo evidence against an antiexcitotoxic mechanism
SP Butcher, DC Henshall, Y Teramura, K Iwasaki, J Sharkey
Journal of Neuroscience 17 (18), 6939-6946, 1997
Epilepsy and apoptosis pathways
DC Henshall, RP Simon
Journal of Cerebral Blood Flow & Metabolism 25 (12), 1557-1572, 2005
Endotoxin preconditioning prevents cellular inflammatory response during ischemic neuroprotection in mice
HL Rosenzweig, NS Lessov, DC Henshall, M Minami, RP Simon, ...
Stroke 35 (11), 2576-2581, 2004
CREB-mediated Bcl-2 protein expression after ischemic preconditioning
R Meller, M Minami, JA Cameron, S Impey, D Chen, JQ Lan, DC Henshall, ...
Journal of Cerebral Blood Flow & Metabolism 25 (2), 234-246, 2005
Involvement of caspase‐3‐like protease in the mechanism of cell death following focally evoked limbic seizures
DC Henshall, J Chen, RP Simon
Journal of neurochemistry 74 (3), 1215-1223, 2000
Alterations in bcl-2 and caspase gene family protein expression in human temporal lobe epilepsy
DC Henshall, RSB Clark, PD Adelson, M Chen, SC Watkins, RP Simon
Neurology 55 (2), 250-257, 2000
miRNA Expression profile after status epilepticus and hippocampal neuroprotection by targeting miR-132
EM Jimenez-Mateos, I Bray, A Sanz-Rodriguez, T Engel, RC McKiernan, ...
The American journal of pathology 179 (5), 2519-2532, 2011
Endotoxin preconditioning protects against the cytotoxic effects of TNFα after stroke: a novel role for TNFα in LPS-ischemic tolerance
HL Rosenzweig, M Minami, NS Lessov, SC Coste, SL Stevens, ...
Journal of Cerebral Blood Flow & Metabolism 27 (10), 1663-1674, 2007
Seizure suppression and neuroprotection by targeting the purinergic P2X7 receptor during status epilepticus in mice
T Engel, R Gomez‐Villafuertes, K Tanaka, G Mesuret, A Sanz‐Rodriguez, ...
The FASEB journal 26 (4), 1616-1628, 2012
Induction of oxidative DNA damage in the peri‐infarct region after permanent focal cerebral ischemia
T Nagayama, J Lan, DC Henshall, D Chen, C O'Horo, RP Simon, J Chen
Journal of neurochemistry 75 (4), 1716-1728, 2000
MicroRNAs in epilepsy: pathophysiology and clinical utility
DC Henshall, HM Hamer, RJ Pasterkamp, DB Goldstein, J Kjems, ...
The Lancet Neurology 15 (13), 1368-1376, 2016
Cleavage of bid may amplify caspase-8-induced neuronal death following focally evoked limbic seizures
DC Henshall, DP Bonislawski, SL Skradski, JQ Lan, R Meller, RP Simon
Neurobiology of disease 8 (4), 568-580, 2001
Apoptosis signalling pathways in seizure-induced neuronal death and epilepsy
DC Henshall
Biochemical society transactions 35 (2), 421-423, 2007
Activation of poly (ADP‐ribose) polymerase in the rat hippocampus may contribute to cellular recovery following sublethal transient global ischemia
T Nagayama, RP Simon, D Chen, DC Henshall, W Pei, RA Stetler, J Chen
Journal of neurochemistry 74 (4), 1636-1645, 2000
Bim regulation may determine hippocampal vulnerability after injurious seizures and in temporal lobe epilepsy
S Shinoda, CK Schindler, R Meller, NK So, T Araki, A Yamamoto, JQ Lan, ...
The Journal of clinical investigation 113 (7), 1059-1068, 2004
Unilateral hippocampal CA3-predominant damage and short latency epileptogenesis after intra-amygdala microinjection of kainic acid in mice
G Mouri, E Jimenez-Mateos, T Engel, M Dunleavy, S Hatazaki, A Paucard, ...
Brain research 1213, 140-151, 2008
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