Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2 JA Johnston, M Kawamura, RA Kirken, YQ Chen, TB Blake, K Shibuya, ... Nature 370 (6485), 151-153, 1994 | 756 | 1994 |
Activation of receptor-associated tyrosine kinase JAK2 by prolactin. H Rui, RA Kirken, WL Farrar Journal of Biological Chemistry 269 (7), 5364-5368, 1994 | 421 | 1994 |
Exploration of Nanoparticle-Mediated Photothermal Effect of TMB-H2O2 Colorimetric System and Its Application in a Visual Quantitative Photothermal Immunoassay G Fu, ST Sanjay, W Zhou, RA Brekken, RA Kirken, XJ Li Analytical chemistry 90 (9), 5930-5937, 2018 | 220 | 2018 |
Prolactin recruits STAT1, STAT3 and STAT5 independent of conserved receptor tyrosines TYR402, TYR479, TYR515 and TYR580 L DaSilva, H Rui, RA Erwin, OMZ Howard, RA Kirken, MG Malabarba, ... Molecular and cellular endocrinology 117 (2), 131-140, 1996 | 219 | 1996 |
JAK3, STAT, and MAPK signaling pathways as novel molecular targets for the tyrphostin AG-490 regulation of IL-2-mediated T cell response LH Wang, RA Kirken, RA Erwin, CR Yu, WL Farrar The Journal of Immunology 162 (7), 3897-3904, 1999 | 211 | 1999 |
Differential control of the phosphorylation state of proline-juxtaposed serine residues Ser725 of Stat5a and Ser730 of Stat5b in prolactin-sensitive cells H Yamashita, J Xu, RA Erwin, WL Farrar, RA Kirken, H Rui Journal of Biological Chemistry 273 (46), 30218-30224, 1998 | 187 | 1998 |
Nitric oxide and thiol redox regulation of Janus kinase activity RJ Duhé, GA Evans, RA Erwin, RA Kirken, GW Cox, WL Farrar Proceedings of the National Academy of Sciences 95 (1), 126-131, 1998 | 186 | 1998 |
Growth signaling and JAK2 association mediated by membrane-proximal cytoplasmic regions of prolactin receptors L DaSilva, OM Howard, H Rui, RA Kirken, WL Farrar Journal of Biological Chemistry 269 (28), 18267-18270, 1994 | 186 | 1994 |
JAK2 activation and cell proliferation induced by antibody-mediated prolactin receptor dimerization H Rui, JJ Lebrun, RA Kirken, PA Kelly, WL Farrar Endocrinology 135 (4), 1299-1306, 1994 | 173 | 1994 |
Selective inhibitor of Janus tyrosine kinase 3, PNU156804, prolongs allograft survival and acts synergistically with cyclosporine but additively with rapamycin SM Stepkowski, RA Erwin-Cohen, F Behbod, ME Wang, X Qu, N Tejpal, ... Blood, The Journal of the American Society of Hematology 99 (2), 680-689, 2002 | 136 | 2002 |
Prolactin activates Ras via signaling proteins SHC, growth factor receptor bound 2, and son of sevenless RA Erwin, RA Kirken, MG Malabarba, WL Farrar, H Rui Endocrinology 136 (8), 3512-3518, 1995 | 135 | 1995 |
Tyrphostin AG-490 inhibits cytokine-mediated JAK3/STAT5a/b signal transduction and cellular proliferation of antigen-activated human T cells RA Kirken, RA Erwin, D Taub, WJ Murphy, F Behbod, L Wang, F Pericle, ... Journal of leukocyte biology 65 (6), 891-899, 1999 | 129 | 1999 |
Transcription factor Stat5 synergizes with androgen receptor in prostate cancer cells SH Tan, A Dagvadorj, F Shen, L Gu, Z Liao, J Abdulghani, Y Zhang, ... Cancer research 68 (1), 236-248, 2008 | 126 | 2008 |
Activation of JAK3, but not JAK1, is critical for IL-2-induced proliferation and STAT5 recruitment by a COOH-terminal region of the IL-2 receptor β-chain RA Kirken, H Rui, GM Malabarba, ZOM Howard, M Kawamura, JJ O'Shea, ... Cytokine 7 (7), 689-700, 1995 | 123 | 1995 |
Transcription factor signal transducer and activator of transcription 5 promotes growth of human prostate cancer cells in vivo A Dagvadorj, RA Kirken, B Leiby, J Karras, MT Nevalainen Clinical Cancer Research 14 (5), 1317-1324, 2008 | 121 | 2008 |
STAT3: an important regulator of multiple cytokine functions SM Stepkowski, W Chen, JA Ross, ZS Nagy, RA Kirken Transplantation 85 (10), 1372-1377, 2008 | 112 | 2008 |
The PHB1/2 phosphocomplex is required for mitochondrial homeostasis and survival of human T cells JA Ross, ZS Nagy, RA Kirken Journal of biological chemistry 283 (8), 4699-4713, 2008 | 111 | 2008 |
Prolactin stimulates serine/tyrosine phosphorylation and formation of heterocomplexes of multiple Stat5 isoforms in Nb2 lymphocytes RA Kirken, MG Malabarba, J Xu, X Liu, WL Farrar, L Hennighausen, ... Journal of Biological Chemistry 272 (22), 14098-14103, 1997 | 109 | 1997 |
Targeted disruption of Stat6 DNA binding activity by an oligonucleotide decoy blocks IL-4–driven TH2 cell response LH Wang, XY Yang, RA Kirken, JH Resau, WL Farrar Blood, The Journal of the American Society of Hematology 95 (4), 1249-1257, 2000 | 105 | 2000 |
Searching in mother nature for anti-cancer activity: anti-proliferative and pro-apoptotic effect elicited by green barley on leukemia/lymphoma cells E Robles-Escajeda, D Lerma, AM Nyakeriga, JA Ross, RA Kirken, ... PloS one 8 (9), e73508, 2013 | 103 | 2013 |