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Alex Binshtok
Alex Binshtok
The Hebrew University School of Medicine, The Edmond and Lily Safra Center for Brain Science
Bestätigte E-Mail-Adresse bei mail.huji.ac.il - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Nociceptors are interleukin-1β sensors
AM Binshtok, H Wang, K Zimmermann, F Amaya, D Vardeh, L Shi, ...
Journal of Neuroscience 28 (52), 14062-14073, 2008
7202008
GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence
I Tegeder, M Costigan, RS Griffin, A Abele, I Belfer, H Schmidt, C Ehnert, ...
Nature medicine 12 (11), 1269-1277, 2006
6522006
Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers
AM Binshtok, BP Bean, CJ Woolf
Nature 449 (7162), 607-610, 2007
5102007
BACE1 regulates voltage-gated sodium channels and neuronal activity
DY Kim, BW Carey, H Wang, LAM Ingano, AM Binshtok, MH Wertz, ...
Nature cell biology 9 (7), 755-764, 2007
3792007
Voltage-gated sodium channels in pain states: role in pathophysiology and targets for treatment
SD Dib-Hajj, AM Binshtok, TR Cummins, MF Jarvis, T Samad, ...
Brain research reviews 60 (1), 65-83, 2009
1842009
Activity-dependent silencing reveals functionally distinct itch-generating sensory neurons
DP Roberson, S Gudes, JM Sprague, HAW Patoski, VK Robson, F Blasl, ...
Nature neuroscience 16 (7), 910-918, 2013
1602013
TRPM2 mediates neutrophil killing of disseminated tumor cells
M Gershkovitz, Y Caspi, T Fainsod-Levi, B Katz, J Michaeli, S Khawaled, ...
Cancer research 78 (10), 2680-2690, 2018
1502018
Coapplication of lidocaine and the permanently charged sodium channel blocker QX-314 produces a long-lasting nociceptive blockade in rodents
AM Binshtok, P Gerner, SB Oh, M Puopolo, S Suzuki, DP Roberson, ...
The Journal of the American Society of Anesthesiologists 111 (1), 127-137, 2009
1442009
Functionally distinct NMDA receptors mediate horizontal connectivity within layer 4 of mouse barrel cortex
IA Fleidervish, AM Binshtok, MJ Gutnick
Neuron 21 (5), 1055-1065, 1998
1241998
The role of slow and persistent TTX-resistant sodium currents in acute tumor necrosis factor-α-mediated increase in nociceptors excitability
S Gudes, O Barkai, Y Caspi, B Katz, S Lev, AM Binshtok
Journal of Neurophysiology 113 (2), 601-619, 2015
992015
Targeting of sodium channel blockers into nociceptors to produce long‐duration analgesia: a systematic study and review
DP Roberson, AM Binshtok, F Blasl, BP Bean, CJ Woolf
British journal of pharmacology 164 (1), 48-58, 2011
992011
Permeation and block of TRPV1 channels by the cationic lidocaine derivative QX-314
M Puopolo, AM Binshtok, GL Yao, SB Oh, CJ Woolf, BP Bean
Journal of neurophysiology 109 (7), 1704-1712, 2013
942013
NMDA receptors in layer 4 spiny stellate cells of the mouse barrel cortex contain the NR2C subunit
AM Binshtok, IA Fleidervish, R Sprengel, MJ Gutnick
Journal of Neuroscience 26 (2), 708-715, 2006
852006
Capsaicin combined with local anesthetics preferentially prolongs sensory/nociceptive block in rat sciatic nerve
P Gerner, AM Binshtok, CF Wang, ND Hevelone, BP Bean, CJ Woolf, ...
The Journal of the American Society of Anesthesiologists 109 (5), 872-878, 2008
842008
Selectively targeting pain in the trigeminal system
HY Kim, K Kim, HY Li, G Chung, CK Park, JS Kim, SJ Jung, MK Lee, ...
Pain 150 (1), 29-40, 2010
712010
Expression of TRPV1 channels after nerve injury provides an essential delivery tool for neuropathic pain attenuation
HM Zakir, RM Mostafeezur, A Suzuki, S Hitomi, I Suzuki, T Maeda, K Seo, ...
Public Library of Science 7 (9), e44023, 2012
602012
Quaternary lidocaine derivative QX-314 activates and permeates human TRPV1 and TRPA1 to produce inhibition of sodium channels and cytotoxicity
T Stueber, MJ Eberhardt, C Hadamitzky, A Jangra, S Schenk, F Dick, ...
Anesthesiology 124 (5), 1153-1165, 2016
492016
Differential cytotoxicity and intracellular calcium-signalling following activation of the calcium-permeable ion channels TRPV1 and TRPA1
T Stueber, MJ Eberhardt, Y Caspi, S Lev, A Binshtok, A Leffler
Cell calcium 68, 34-44, 2017
402017
KV7/M channels as targets for lipopolysaccharide‐induced inflammatory neuronal hyperexcitability
A Tzour, H Leibovich, O Barkai, Y Biala, S Lev, Y Yaari, AM Binshtok
The Journal of physiology 595 (3), 713-738, 2017
362017
Privileged crosstalk between TRPV1 channels and mitochondrial calcium shuttling machinery controls nociception
II Nita, Y Caspi, S Gudes, D Fishman, S Lev, M Hersfinkel, I Sekler, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (12), 2868-2880, 2016
362016
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