Miha Milek
Miha Milek
Core Unit Bioinformatics, Berlin Institute of Health
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The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts
AG Baltz, M Munschauer, B Schwanhäusser, A Vasile, Y Murakawa, ...
Molecular cell 46 (5), 674-690, 2012
Heterozygosity at the TPMT gene locus, augmented by mutated MTHFR gene, predisposes to 6-MP related toxicities in childhood ALL patients
N Karas-Kuzelicki, J Jazbec, M Milek, I Mlinaric-Rascan
Leukemia 23 (5), 971-974, 2009
Phosphorylation of the ribosomal protein RPL12/uL11 affects translation during mitosis
K Imami, M Milek, B Bogdanow, T Yasuda, N Kastelic, H Zauber, ...
Molecular cell 72 (1), 84-98. e9, 2018
Transcriptome-wide analysis of protein–RNA interactions using high-throughput sequencing
M Milek, E Wyler, M Landthaler
Seminars in cell & developmental biology 23 (2), 206-212, 2012
DDX54 regulates transcriptome dynamics during DNA damage response
M Milek, K Imami, N Mukherjee, F De Bortoli, U Zinnall, O Hazapis, ...
Genome research 27 (8), 1344-1359, 2017
Loss of m1acp3Ψ ribosomal RNA modification is a major feature of cancer
A Babaian, K Rothe, D Girodat, I Minia, S Djondovic, M Milek, SES Miko, ...
Cell reports 31 (5), 107611, 2020
S-adenosylmethionine regulates thiopurine methyltransferase activity and decreases 6-mercaptopurine cytotoxicity in MOLT lymphoblasts
M Milek, NK Kuzelicki, A Smid, I Mlinaric-Rascan
Biochemical pharmacology 77 (12), 1845-1853, 2009
Surface active stabilizer Tyloxapol in colloidal dispersions exerts cytostatic effects and apoptotic dismissal of cells
J Kristl, K Teskac, M Milek, I Mlinaric-Rascan
Toxicology and applied pharmacology 232 (2), 218-225, 2008
Thiopurine S-methyltransferase pharmacogenetics: genotype to phenotype correlation in the Slovenian population
M Milek, J Murn, Z Jaksic, JL Bajalo, J Jazbec, IM Rascan
Pharmacology 77 (3), 105-114, 2006
5, 10-Methylenetetrahydrofolate reductase (MTHFR) low activity genotypes reduce the risk of relapse-related acute lymphoblastic leukemia (ALL)
NK Kuzelicki, M Milek, J Jazbec, I Mlinaric-Rascan
Leukemia research 33 (10), 1344-1348, 2009
The human ZC3H3 and RBM26/27 proteins are critical for PAXT-mediated nuclear RNA decay
T Silla, M Schmid, Y Dou, W Garland, M Milek, K Imami, D Johnsen, ...
Nucleic acids research 48 (5), 2518-2530, 2020
MTHFR and TYMS genotypes influence TPMT activity and its differential modulation in males and females
N Karas-Kuzelicki, M Milek, I Mlinaric-Rascan
Clinical biochemistry 43 (1-2), 37-42, 2010
Post-translational stabilization of thiopurine S-methyltransferase by S-adenosyl-L-methionine reveals regulation of TPMT* 1 and* 3C allozymes
M Milek, A Smid, R Tamm, NK Kuzelicki, A Metspalu, I Mlinaric-Rascan
Biochemical pharmacology 83 (7), 969-976, 2012
Association of ITPA genotype with event-free survival and relapse rates in children with acute lymphoblastic leukemia undergoing maintenance therapy
A Smid, N Karas-Kuzelicki, M Milek, J Jazbec, I Mlinaric-Rascan
PLoS One 9 (10), e109551, 2014
A novel gene delivery system for stable transfection of thiopurine-S-methyltransferase gene in versatile cell types
R Egle, M Milek, I Mlinarič-Raščan, A Fahr, J Kristl
European journal of pharmaceutics and biopharmaceutics 69 (1), 23-30, 2008
Expanding the map of protein-RNA interaction sites via cell fusion followed by PAR-CLIP
F Hinze, P Drewe-Boss, M Milek, U Ohler, M Landthaler, M Gotthardt
RNA biology 15 (3), 359-368, 2018
CRNKL1 is a highly selective regulator of intron-retaining HIV-1 and cellular mRNAs
H Xiao, E Wyler, M Milek, B Grewe, P Kirchner, A Ekici, ABOV Silva, ...
MBio 12 (1), e02525-20, 2021
Systematic Detection of Poly(A)+ RNA-Interacting Proteins and Their Differential Binding
M Milek, M Landthaler
RNA Detection: Methods and Protocols, 405-417, 2018
HDLBP binds ER-targeted mRNAs by multivalent interactions to promote protein synthesis of transmembrane and secreted proteins
U Zinnall, M Milek, I Minia, CH Vieira-Vieira, S Müller, G Mastrobuoni, ...
Nature Communications 13 (1), 2727, 2022
S-Adenosylmethionine: A Novel Factor in the Individualization of Thiopurine Therapy
I Mlinaric-Rascan, M Milek, A Smid, NK Kuzelicki
Clinical Applications of Pharmacogenetics, 95, 2012
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