Nigel Scrutton
Nigel Scrutton
Professor of Enzymology, Manchester Institute of Biotechnology (MIB) and School of Chemistry
Bestätigte E-Mail-Adresse bei manchester.ac.uk - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Redesign of the coenzyme specificity of a dehydrogenase by protein engineering
NS Scrutton, A Berry, RN Perham
Nature 343 (6253), 38-43, 1990
8051990
Atomic description of an enzyme reaction dominated by proton tunneling
L Masgrau, A Roujeinikova, LO Johannissen, P Hothi, J Basran, ...
Science 312 (5771), 237-241, 2006
3522006
Cation-π bonding and amino-aromatic interactions in the biomolecular recognition of substituted ammonium ligands
NS Scrutton, ARC Raine
Biochemical Journal 319 (1), 1-8, 1996
2761996
Enzymatic H-transfer requires vibration-driven extreme tunneling
J Basran, MJ Sutcliffe, NS Scrutton
Biochemistry 38 (10), 3218-3222, 1999
2651999
Biocatalytic reductions and chemical versatility of the old yellow enzyme family of flavoprotein oxidoreductases
HS Toogood, JM Gardiner, NS Scrutton
ChemCatChem 2 (8), 892-914, 2010
2582010
Good vibrations in enzyme-catalysed reactions
S Hay, NS Scrutton
Nature chemistry 4 (3), 161-168, 2012
2502012
Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades
FG Mutti, T Knaus, NS Scrutton, M Breuer, NJ Turner
Science 349 (6255), 1525-1529, 2015
2422015
Covalent attachment of flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) to enzymes: the current state of affairs
M Mewies, WS McIntire, NS Scrutton
Protein Science 7 (1), 7-20, 1998
2311998
Biotransformation of explosives by the old yellow enzyme family of flavoproteins
RE Williams, DA Rathbone, NS Scrutton, NC Bruce
Applied and Environmental Microbiology 70 (6), 3566-3574, 2004
1992004
complexity
S Brenner, S Hay, AW Munro, NS Scrutton
1602008
What’s in a covalent bond?
DPHM Heuts, NS Scrutton, WS McIntire, MW Fraaije
The FEBS journal 276 (13), 3405-3427, 2009
1592009
A new conceptual framework for enzyme catalysis: Hydrogen tunneling coupled to enzyme dynamics in flavoprotein and quinoprotein enzymes
MJ Sutcliffe, NS Scrutton
European Journal of Biochemistry 269 (13), 3096-3102, 2002
1582002
Biodiversity of cytochrome P450 redox systems
KJ McLean, M Sabri, KR Marshall, RJ Lawson, DG Lewis, D Clift, ...
Biochemical Society Transactions 33 (4), 796-801, 2005
1432005
New cofactor supports α, β-unsaturated acid decarboxylation via 1, 3-dipolar cycloaddition
KAP Payne, MD White, K Fisher, B Khara, SS Bailey, D Parker, ...
Nature 522 (7557), 497-501, 2015
1402015
Biologic functions of the G12 subfamily of heterotrimeric g proteins: growth, migration, and metastasis
P Kelly, PJ Casey, TE Meigs
Biochemistry 46 (23), 6677-6687, 2007
1342007
Creation of an NADP-dependent pyruvate dehydrogenase multienzyme complex by protein engineering
JA Bocanegra, NS Scrutton, RN Perham
Biochemistry 32 (11), 2737-2740, 1993
1291993
UbiX is a flavin prenyltransferase required for bacterial ubiquinone biosynthesis
MD White, KAP Payne, K Fisher, SA Marshall, D Parker, NJW Rattray, ...
Nature 522 (7557), 502-506, 2015
1282015
The dimeric form of flavocytochrome P450 BM3 is catalytically functional as a fatty acid hydroxylase
R Neeli, HM Girvan, A Lawrence, MJ Warren, D Leys, NS Scrutton, ...
FEBS letters 579 (25), 5582-5588, 2005
1222005
Importance of barrier shape in enzyme-catalyzed reactions vibrationally assisted hydrogen tunneling in tryptophan tryptophylquinone-dependent amine dehydrogenases
J Basran, S Patel, MJ Sutcliffe, NS Scrutton
Journal of Biological Chemistry 276 (9), 6234-6242, 2001
1202001
Extensive conformational sampling in a ternary electron transfer complex
D Leys, J Basran, F Talfournier, MJ Sutcliffe, NS Scrutton
Nature Structural & Molecular Biology 10 (3), 219-225, 2003
1192003
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