| CAR T cell immunotherapy for human cancer CH June, RS O’Connor, OU Kawalekar, S Ghassemi, MC Milone Science 359 (6382), 1361-1365, 2018 | 2405 | 2018 |
| Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia JA Fraietta, SF Lacey, EJ Orlando, I Pruteanu-Malinici, M Gohil, S Lundh, ... Nature medicine 24 (5), 563-571, 2018 | 1345 | 2018 |
| Distinct signaling of coreceptors regulates specific metabolism pathways and impacts memory development in CAR T cells OU Kawalekar, RS O’Connor, JA Fraietta, L Guo, SE McGettigan, ... Immunity 44 (2), 380-390, 2016 | 1073 | 2016 |
| Human chimeric antigen receptor macrophages for cancer immunotherapy M Klichinsky, M Ruella, O Shestova, XM Lu, A Best, M Zeeman, ... Nature biotechnology 38 (8), 947-953, 2020 | 858 | 2020 |
| Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis Y Xiang, ZE Stine, J Xia, Y Lu, RS O’Connor, BJ Altman, AL Hsieh, ... The Journal of clinical investigation 125 (6), 2293-2306, 2015 | 444 | 2015 |
| Substrate rigidity regulates human T cell activation and proliferation RS O’Connor, X Hao, K Shen, K Bashour, T Akimova, WW Hancock, ... The Journal of Immunology 189 (3), 1330-1339, 2012 | 304 | 2012 |
| F-actin polymerization and retrograde flow drive sustained PLCγ1 signaling during T cell activation A Babich, S Li, RS O'Connor, MC Milone, BD Freedman, JK Burkhardt Journal of Cell Biology 197 (6), 775-787, 2012 | 237 | 2012 |
| Reducing Ex Vivo Culture Improves the Antileukemic Activity of Chimeric Antigen Receptor (CAR) T Cells S Ghassemi, S Nunez-Cruz, RS O'Connor, JA Fraietta, PR Patel, ... Cancer immunology research 6 (9), 1100-1109, 2018 | 235 | 2018 |
| Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47− mediated ‘don’t-eat-me’signal M Liu, RS O’Connor, S Trefely, K Graham, NW Snyder, GL Beatty Nature immunology 20 (3), 265-275, 2019 | 212 | 2019 |
| CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapy A Rodriguez-Garcia, RC Lynn, M Poussin, MA Eiva, LC Shaw, ... Nature communications 12 (1), 877, 2021 | 172 | 2021 |
| The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations RS O’Connor, L Guo, S Ghassemi, NW Snyder, AJ Worth, L Weng, Y Kam, ... Scientific reports 8 (1), 6289, 2018 | 153 | 2018 |
| Point: Counterpoint: Satellite cell addition is/is not obligatory for skeletal muscle hypertrophy RS O'Connor, GK Pavlath Journal of applied physiology 103 (3), 1099-1100, 2007 | 152 | 2007 |
| Point: Counterpoint: Satellite cell addition is/is not obligatory for skeletal muscle hypertrophy RS O'Connor, GK Pavlath Journal of applied physiology 103 (3), 1099-1100, 2007 | 152 | 2007 |
| 4-1BB costimulation promotes CAR T cell survival through noncanonical NF-κB signaling BI Philipson, RS O’Connor, MJ May, CH June, SM Albelda, MC Milone Science signaling 13 (625), eaay8248, 2020 | 146 | 2020 |
| A combinatorial role for NFAT5 in both myoblast migration and differentiation during skeletal muscle myogenesis RS O'Connor, ST Mills, KA Jones, SN Ho, GK Pavlath Journal of cell science 120 (1), 149-159, 2007 | 144 | 2007 |
| Sca-1 negatively regulates proliferation and differentiation of muscle cells PO Mitchell, T Mills, RS O'Connor, T Graubert, E Dzierzak, GK Pavlath Developmental biology 283 (1), 240-252, 2005 | 126 | 2005 |
| Rapid manufacturing of non-activated potent CAR T cells S Ghassemi, JS Durgin, S Nunez-Cruz, J Patel, J Leferovich, M Pinzone, ... Nature biomedical engineering 6 (2), 118-128, 2022 | 121 | 2022 |
| Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality A Saha, RS O’Connor, G Thangavelu, SB Lovitch, DB Dandamudi, ... The Journal of clinical investigation 126 (7), 2642-2660, 2016 | 95 | 2016 |
| Imaging CAR T cell trafficking with eDHFR as a PET reporter gene MA Sellmyer, SA Richman, K Lohith, C Hou, CC Weng, RH Mach, ... Molecular Therapy 28 (1), 42-51, 2020 | 81 | 2020 |
| Genomic and clinical analysis of amplification of the 13q31 chromosomal region in alveolar rhabdomyosarcoma: a report from the Children's Oncology Group JL Reichek, F Duan, LM Smith, DM Gustafson, RS O'Connor, C Zhang, ... Clinical Cancer Research 17 (6), 1463-1473, 2011 | 81 | 2011 |
