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Philip D Dunne
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QuPath: Open source software for digital pathology image analysis
P Bankhead, MB Loughrey, JA Fernández, Y Dombrowski, DG McArt, ...
Scientific reports 7 (1), 1-7, 2017
50622017
Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning
K Sirinukunwattana, E Domingo, SD Richman, KL Redmond, A Blake, ...
Gut 70 (3), 544-554, 2021
1832021
QuPath: open source software for digital pathology image analysis. Sci Rep 7: 16878
P Bankhead, MB Loughrey, JA Fernández, Y Dombrowski, DG McArt, ...
1772017
Challenging the cancer molecular stratification dogma: intratumoral heterogeneity undermines consensus molecular subtypes and potential diagnostic value in colorectal cancer
PD Dunne, DG McArt, CA Bradley, PG O'Reilly, HL Barrett, R Cummins, ...
Clinical Cancer Research 22 (16), 4095-4104, 2016
1652016
The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer
AK Najumudeen, F Ceteci, SK Fey, G Hamm, RT Steven, H Hall, ...
Nature genetics 53 (1), 16-26, 2021
1482021
EphA2 expression is a key driver of migration and invasion and a poor prognostic marker in colorectal cancer
PD Dunne, S Dasgupta, JK Blayney, DG McArt, KL Redmond, JA Weir, ...
Clinical Cancer Research 22 (1), 230-242, 2016
1352016
AXL is a key regulator of inherent and chemotherapy-induced invasion and predicts a poor clinical outcome in early-stage colon cancer
PD Dunne, DG McArt, JK Blayney, M Kalimutho, S Greer, T Wang, ...
Clinical Cancer Research 20 (1), 164-175, 2014
1162014
ADAM17-dependent c-MET-STAT3 signaling mediates resistance to MEK inhibitors in KRAS mutant colorectal cancer
S Van Schaeybroeck, M Kalimutho, PD Dunne, R Carson, W Allen, ...
Cell reports 7 (6), 1940-1955, 2014
1112014
Fibroblast growth factor receptor 4 (FGFR4): a targetable regulator of drug resistance in colorectal cancer
RC Turkington, DB Longley, WL Allen, L Stevenson, K McLaughlin, ...
Cell death & disease 5 (2), e1046-e1046, 2014
1082014
Cancer-cell intrinsic gene expression signatures overcome intratumoural heterogeneity bias in colorectal cancer patient classification
PD Dunne, M Alderdice, PG O'Reilly, AC Roddy, AMB McCorry, ...
Nature communications 8 (1), 15657, 2017
902017
DNMT1 deficiency triggers mismatch repair defects in human cells through depletion of repair protein levels in a process involving the DNA damage response
JEP Loughery, PD Dunne, KM O'Neill, RR Meehan, JR McDaid, ...
Human molecular genetics 20 (16), 3241-3255, 2011
852011
Validation of the systematic scoring of immunohistochemically stained tumour tissue microarrays using QuPath digital image analysis
MB Loughrey, P Bankhead, HG Coleman, RS Hagan, S Craig, ...
Histopathology 73 (2), 327-338, 2018
812018
Stromal Cell PD-L1 Inhibits CD8+ T-cell Antitumor Immune Responses and Promotes Colon Cancer
G O'Malley, O Treacy, K Lynch, SD Naicker, NA Leonard, P Lohan, ...
Cancer immunology research 6 (11), 1426-1441, 2018
722018
QuPath: Open source software for digital pathology image analysis. Sci Rep. 2017; 7 (1): 16878
P Bankhead, MB Loughrey, JA Fernandez, Y Dombrowski, DG McArt, ...
Journal for ImmunoTherapy of Cancer (JITC) preprint. The copyright holder …, 0
69
Transcriptional subtyping and CD8 immunohistochemistry identifies patients with stage II and III colorectal cancer with poor prognosis who benefit from adjuvant chemotherapy
WL Allen, PD Dunne, S McDade, E Scanlon, M Loughrey, HG Coleman, ...
JCO precision oncology 2, 1-15, 2018
682018
Prospective patient stratification into robust cancer‐cell intrinsic subtypes from colorectal cancer biopsies
M Alderdice, SD Richman, S Gollins, JP Stewart, C Hurt, R Adams, ...
The Journal of pathology 245 (1), 19-28, 2018
672018
Back to the future: routine morphological assessment of the tumour microenvironment is prognostic in stage II/III colon cancer in a large population‐based study
SO Hynes, HG Coleman, PJ Kelly, S Irwin, RF O'Neill, RT Gray, ...
Histopathology 71 (1), 12-26, 2017
672017
Gremlin1 plays a key role in kidney development and renal fibrosis
RH Church, I Ali, M Tate, D Lavin, A Krishnakumar, HM Kok, ...
American Journal of Physiology-Renal Physiology 312 (6), F1141-F1157, 2017
672017
Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification
SO Kleeman, VH Koelzer, HJS Jones, EG Vazquez, H Davis, JE East, ...
Gut 69 (6), 1092-1103, 2020
652020
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia
EG Vazquez, N Nasreddin, GN Valbuena, EJ Mulholland, ...
Cell Stem Cell 29 (8), 1213-1228. e8, 2022
572022
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