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David Hay
David Hay
University of Edinburgh
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Zitiert von
Jahr
Generation of functional human hepatic endoderm from human induced pluripotent stem cells
GJ Sullivan, DC Hay, IH Park, J Fletcher, Z Hannoun, CM Payne, ...
Hepatology 51 (1), 329-335, 2010
5822010
Efficient differentiation of hepatocytes from human embryonic stem cells exhibiting markers recapitulating liver development in vivo
DC Hay, D Zhao, J Fletcher, ZA Hewitt, D McLean, ...
Stem cells 26 (4), 894-902, 2008
5412008
Highly efficient differentiation of hESCs to functional hepatic endoderm requires ActivinA and Wnt3a signaling
DC Hay, J Fletcher, C Payne, JD Terrace, RCJ Gallagher, J Snoeys, ...
Proceedings of the National Academy of Sciences 105 (34), 12301-12306, 2008
5312008
Oct‐4 knockdown induces similar patterns of endoderm and trophoblast differentiation markers in human and mouse embryonic stem cells
DC Hay, L Sutherland, J Clark, T Burdon
Stem cells 22 (2), 225-235, 2004
5162004
Hepatic progenitor cells of biliary origin with liver repopulation capacity
WY Lu, TG Bird, L Boulter, A Tsuchiya, AM Cole, T Hay, RV Guest, ...
Nature cell biology 17 (8), 971-983, 2015
4582015
Lineage-specific distribution of high levels of genomic
A Ruzov, Y Tsenkina, A Serio, T Dudnakova, J Fletcher, Y Bai, ...
Cell research 21 (9), 1332-1342, 2011
2332011
Direct differentiation of human embryonic stem cells to hepatocyte-like cells exhibiting functional activities
DC Hay, D Zhao, A Ross, R Mandalam, J Lebkowski, W Cui
Cloning and stem cells 9 (1), 51-62, 2007
2272007
Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells
P Godoy, W Schmidt-Heck, K Natarajan, B Lucendo-Villarin, D Szkolnicka, ...
Journal of hepatology 63 (4), 934-942, 2015
1962015
Recombinant laminins drive the differentiation and self-organization of hESC-derived hepatocytes
K Cameron, R Tan, W Schmidt-Heck, G Campos, MJ Lyall, Y Wang, ...
Stem cell reports 5 (6), 1250-1262, 2015
1562015
Developing high-fidelity hepatotoxicity models from pluripotent stem cells
CN Medine, B Lucendo-Villarin, C Storck, F Wang, D Szkolnicka, F Khan, ...
Stem cells translational medicine 2 (7), 505-509, 2013
1562013
Post-translational modification by SUMO
Z Hannoun, S Greenhough, E Jaffray, RT Hay, DC Hay
Toxicology 278 (3), 288-293, 2010
1552010
Liver tissue engineering and cell sources: issues and challenges
AA Palakkan, DC Hay, AK PR, K TV, JA Ross
Liver international 33 (5), 666-676, 2013
1522013
Concise review: workshop review: understanding and assessing the risks of stem cell-based therapies
JA Heslop, TG Hammond, I Santeramo, A Tort Piella, I Hopp, J Zhou, ...
Stem cells translational medicine 4 (4), 389-400, 2015
1342015
Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile
JA Heslop, C Rowe, J Walsh, R Sison-Young, R Jenkins, L Kamalian, ...
Archives of toxicology 91, 439-452, 2017
1292017
Accurate prediction of drug-induced liver injury using stem cell-derived populations
D Szkolnicka, SL Farnworth, B Lucendo-Villarin, C Storck, W Zhou, ...
Stem cells translational medicine 3 (2), 141-148, 2014
1242014
Unbiased screening of polymer libraries to define novel substrates for functional hepatocytes with inducible drug metabolism
DC Hay, S Pernagallo, JJ Diaz-Mochon, CN Medine, S Greenhough, ...
Stem cell research 6 (2), 92-102, 2011
1242011
Fluid shear stress modulation of hepatocyte-like cell function
H Rashidi, S Alhaque, D Szkolnicka, O Flint, DC Hay
Archives of toxicology 90, 1757-1761, 2016
1202016
Progress and future challenges in stem cell-derived liver technologies
DM Dalgetty, CN Medine, JP Iredale, DC Hay
American Journal of Physiology-Gastrointestinal and Liver Physiology 297 (2 …, 2009
1172009
3D human liver tissue from pluripotent stem cells displays stable phenotype in vitro and supports compromised liver function in vivo
H Rashidi, NT Luu, SM Alwahsh, M Ginai, S Alhaque, H Dong, RA Tomaz, ...
Archives of toxicology 92, 3117-3129, 2018
1092018
Pluripotent stem cell derived hepatocyte like cells and their potential in toxicity screening
S Greenhough, CN Medine, DC Hay
Toxicology 278 (3), 250-255, 2010
932010
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