| Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease C Janus, J Pearson, JA McLaurin, PM Mathews, Y Jiang, SD Schmidt, ... Nature 408 (6815), 979-982, 2000 | 2023 | 2000 |
| Therapeutically effective antibodies against amyloid-β peptide target amyloid-β residues 4–10 and inhibit cytotoxicity and fibrillogenesis J McLaurin, R Cecal, ME Kierstead, X Tian, AL Phinney, M Manea, ... Nature medicine 8 (11), 1263-1269, 2002 | 567 | 2002 |
| Interactions between β-amyloid and central cholinergic neurons: implications for Alzheimer’s disease S Kar, SPM Slowikowski, D Westaway, HTJ Mount Journal of Psychiatry and Neuroscience 29 (6), 427-441, 2004 | 492 | 2004 |
| Cyclohexanehexol inhibitors of Aβ aggregation prevent and reverse Alzheimer phenotype in a mouse model JA McLaurin, ME Kierstead, ME Brown, CA Hawkes, MHL Lambermon, ... Nature medicine 12 (7), 801-808, 2006 | 452 | 2006 |
| Brain-derived neurotrophic factor rapidly enhances phosphorylation of the postsynaptic N-methyl-d-aspartate receptor subunit 1 PC Suen, K Wu, ES Levine, HTJ Mount, JL Xu, SY Lin, IB Black Proceedings of the National Academy of Sciences 94 (15), 8191-8195, 1997 | 373 | 1997 |
| BDNF acutely increases tyrosine phosphorylation of the NMDA receptor subunit 2B in cortical and hippocampal postsynaptic densities SY Lin, K Wu, ES Levine, HTJ Mount, PC Suen, IB Black Molecular brain research 55 (1), 20-27, 1998 | 340 | 1998 |
| α5GABAA receptors mediate the amnestic but not sedative-hypnotic effects of the general anesthetic etomidate VY Cheng, LJ Martin, EM Elliott, JH Kim, HTJ Mount, FA Taverna, ... Journal of Neuroscience 26 (14), 3713-3720, 2006 | 296 | 2006 |
| Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of β-catenin, a component of the presenilin protein complex M Nishimura, G Yu, G Levesque, DM Zhang, L Ruel, F Chen, P Milman, ... Nature medicine 5 (2), 164-169, 1999 | 276 | 1999 |
| Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease S Peng, DJ Garzon, M Marchese, W Klein, SD Ginsberg, BM Francis, ... Journal of Neuroscience 29 (29), 9321-9329, 2009 | 246 | 2009 |
| Glial cell line-derived neurotrophic factor promotes the survival and morphologic differentiation of Purkinje cells. HTJ Mount, DO Dean, J Alberch, CF Dreyfus, IB Black Proceedings of the National Academy of Sciences 92 (20), 9092-9096, 1995 | 221 | 1995 |
| APH-1 interacts with mature and immature forms of presenilins and nicastrin and may play a role in maturation of presenilin· nicastrin complexes Y Gu, F Chen, N Sanjo, T Kawarai, H Hasegawa, M Duthie, W Li, X Ruan, ... Journal of Biological Chemistry 278 (9), 7374-7380, 2003 | 212 | 2003 |
| Mature Glycosylation and Trafficking of Nicastrin Modulate Its Binding to Presenilins* 210 DS Yang, A Tandon, F Chen, G Yu, H Yu, S Arawaka, H Hasegawa, ... Journal of Biological Chemistry 277 (31), 28135-28142, 2002 | 209 | 2002 |
| Unesterified docosahexaenoic acid is protective in neuroinflammation SK Orr, S Palumbo, F Bosetti, HT Mount, JX Kang, CE Greenwood, ... Journal of neurochemistry 127 (3), 378-393, 2013 | 180 | 2013 |
| The CNS glycoprotein Shadoo has PrPC‐like protective properties and displays reduced levels in prion infections JC Watts, B Drisaldi, V Ng, J Yang, B Strome, P Horne, MS Sy, L Yoong, ... The EMBO journal 26 (17), 4038-4050, 2007 | 173 | 2007 |
| Reduced fear and aggression and altered serotonin metabolism in Gtf2ird1‐targeted mice EJ Young, T Lipina, E Tam, A Mandel, SJ Clapcote, AR Bechard, ... Genes, Brain and Behavior 7 (2), 224-234, 2008 | 166 | 2008 |
| Inflammatory biomarkers in Alzheimer's disease plasma AR Morgan, S Touchard, C Leckey, C O'Hagan, AJ Nevado-Holgado, ... Alzheimer's & dementia 15 (6), 776-787, 2019 | 140 | 2019 |
| Presenilin 1 mutations activate γ42-secretase but reciprocally inhibit ε-secretase cleavage of amyloid precursor protein (APP) and S3-cleavage of notch F Chen, YJ Gu, H Hasegawa, X Ruan, S Arawaka, P Fraser, D Westaway, ... Journal of Biological Chemistry 277 (39), 36521-36526, 2002 | 138 | 2002 |
| Functional trkB neurotrophin receptors are intrinsic components of the adult brain postsynaptic density K Wu, J Xu, P Suen, E Levine, Y Huang, HTJ Mount, S Lin, IB Black Molecular brain research 43 (1-2), 286-290, 1996 | 135 | 1996 |
| Object recognition memory and BDNF expression are reduced in young TgCRND8 mice BM Francis, J Kim, ME Barakat, S Fraenkl, YH Yücel, S Peng, B Michalski, ... Neurobiology of aging 33 (3), 555-563, 2012 | 129 | 2012 |
| The low density lipoprotein receptor is not necessary for maintaining mouse brain polyunsaturated fatty acid concentrations CT Chen, DWL Ma, JH Kim, HTJ Mount, RP Bazinet Journal of lipid research 49 (1), 147-152, 2008 | 114 | 2008 |
