Antioxidants accelerate lung cancer progression in mice VI Sayin, MX Ibrahim, E Larsson, JA Nilsson, P Lindahl, MO Bergo Science translational medicine 6 (221), 221ra15-221ra15, 2014 | 892 | 2014 |
Bioinspired exosome-mimetic nanovesicles for targeted delivery of chemotherapeutics to malignant tumors SC Jang, OY Kim, CM Yoon, DS Choi, TY Roh, J Park, J Nilsson, J Lotvall, ... ACS nano 7 (9), 7698-7710, 2013 | 886 | 2013 |
DNA damage primes the type I interferon system via the cytosolic DNA sensor STING to promote anti-microbial innate immunity A Härtlova, SF Erttmann, FAM Raffi, AM Schmalz, U Resch, S Anugula, ... Immunity 42 (2), 332-343, 2015 | 676 | 2015 |
Antioxidants can increase melanoma metastasis in mice K Le Gal, MX Ibrahim, C Wiel, VI Sayin, MK Akula, C Karlsson, MG Dalin, ... Science translational medicine 7 (308), 308re8-308re8, 2015 | 645 | 2015 |
c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression TA Baudino, C McKay, H Pendeville-Samain, JA Nilsson, KH Maclean, ... Genes & development 16 (19), 2530-2543, 2002 | 604 | 2002 |
Myc pathways provoking cell suicide and cancer JA Nilsson, JL Cleveland Oncogene 22 (56), 9007-9021, 2003 | 597 | 2003 |
Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants MT Hemann, A Bric, J Teruya-Feldstein, A Herbst, JA Nilsson, ... Nature 436 (7052), 807-811, 2005 | 588 | 2005 |
MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool H Gad, T Koolmeister, AS Jemth, S Eshtad, SA Jacques, CE Ström, ... Nature 508 (7495), 215-221, 2014 | 537 | 2014 |
Systematic analysis of noncoding somatic mutations and gene expression alterations across 14 tumor types NJ Fredriksson, L Ny, JA Nilsson, E Larsson Nature genetics 46 (12), 1258-1263, 2014 | 332 | 2014 |
BET and HDAC inhibitors induce similar genes and biological effects and synergize to kill in Myc-induced murine lymphoma J Bhadury, LM Nilsson, S Veppil Muralidharan, LC Green, Z Li, ... Proceedings of the National Academy of Sciences 111 (26), E2721-E2730, 2014 | 250 | 2014 |
Aurora kinases A and B are up-regulated by Myc and are essential for maintenance of the malignant state J Den Hollander, S Rimpi, JR Doherty, M Rudelius, A Buck, A Hoellein, ... Blood, The Journal of the American Society of Hematology 116 (9), 1498-1505, 2010 | 250 | 2010 |
Targeting ornithine decarboxylase in Myc-induced lymphomagenesis prevents tumor formation JA Nilsson, UB Keller, TA Baudino, C Yang, S Norton, JA Old, LM Nilsson, ... Cancer cell 7 (5), 433-444, 2005 | 223 | 2005 |
RNAi delivery by exosome-mimetic nanovesicles–Implications for targeting c-Myc in cancer TR Lunavat, SC Jang, L Nilsson, HT Park, G Repiska, C Lässer, ... Biomaterials 102, 231-238, 2016 | 209 | 2016 |
Small RNA deep sequencing discriminates subsets of extracellular vesicles released by melanoma cells–Evidence of unique microRNA cargos TR Lunavat, L Cheng, DK Kim, J Bhadury, SC Jang, C Lässer, ... RNA biology 12 (8), 810-823, 2015 | 204 | 2015 |
Selection against PUMA Gene Expression in Myc-Driven B-Cell Lymphomagenesis SP Garrison, JR Jeffers, C Yang, JA Nilsson, MA Hall, JE Rehg, W Yue, ... Molecular and cellular biology 28 (17), 5391-5402, 2008 | 185 | 2008 |
c-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XL KH Maclean, UB Keller, C Rodriguez-Galindo, JA Nilsson, JL Cleveland Molecular and cellular biology, 2003 | 173 | 2003 |
Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model H Jespersen, MF Lindberg, M Donia, EMV Söderberg, R Andersen, ... Nature communications 8 (1), 707, 2017 | 167 | 2017 |
An approach to suppress the evolution of resistance in BRAFV600E-mutant cancer Y Xue, L Martelotto, T Baslan, A Vides, M Solomon, TT Mai, N Chaudhary, ... Nature medicine 23 (8), 929-937, 2017 | 160 | 2017 |
Therapeutic implications for the induced levels of Chk1 in Myc-expressing cancer cells A Höglund, LM Nilsson, SV Muralidharan, LA Hasvold, P Merta, ... Clinical Cancer Research 17 (22), 7067-7079, 2011 | 147 | 2011 |
Endosomal signalling via exosome surface TGFβ-1 GV Shelke, Y Yin, SC Jang, C Lässer, S Wennmalm, HJ Hoffmann, L Li, ... Journal of extracellular vesicles 8 (1), 1650458, 2019 | 143 | 2019 |